PMID- 37755748
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20231003
IS  - 2305-6304 (Electronic)
IS  - 2305-6304 (Linking)
VI  - 11
IP  - 9
DP  - 2023 Aug 28
TI  - Developing an Improved Strategy for the Analysis of Polychlorinated 
      Dibenzo-p-Dioxins/Furans and Dioxin-like Polychlorinated Biphenyls in 
      Contaminated Soils Using a Combination of a One-Step Cleanup Method and Gas 
      Chromatography with Triple Quadrupole Mass Spectrometry.
LID - 10.3390/toxics11090738 [doi]
LID - 738
AB  - Soils contaminated with polychlorodibenzo-p-dioxins (PCDDs), 
      polychlorodibenzofurans (PCDFs), and dioxin-like (dl) polychlorinated biphenyls 
      (PCBs), known as persistent organic pollutants (POPs), have garnered global 
      attention because of their toxicity and persistence in the environment. The 
      standard method for target analytes has been used; however, it is an obstacle in 
      large-scale sample analysis due to the comprehensive sample preparation and 
      high-cost instrumental analysis. Thus, analytical development of inexpensive 
      methods with lower barriers to determine PCDDs/Fs and dl-PCBs in soil is needed. 
      In this study, a one-step cleanup method was developed and validated by combining 
      a multilayer silica gel column and Florisil micro-column followed by gas 
      chromatography with triple quadrupole mass spectrometry (GC-QqQ-MS/MS). To 
      optimize the separation and quantification of 17 PCDDs/Fs and 12 dl-PCBs in 
      soils, the sample cleanup and instrumental conditions were investigated. For 
      quantification method validation, spiking experiments were conducted to determine 
      the linearity of the calibration, recovery, and method detection limit of 
      PCDDs/Fs and dl-PCBs using isotopic dilution GC-QqQ-MS/MS. The applicability of 
      the simultaneous determination of PCDDs/Fs and dl-PCBs was confirmed by the 
      recovery of native target congeners and labeled surrogate congeners spiked into 
      the quality-control and actual soil samples. The results were in good agreement 
      with the requirements imposed by standard methods. The findings in this work 
      demonstrated the high accessibility of the sample cleanup and analysis methods 
      for the efficient determination of PCDDs/Fs and dl-PCBs in contaminated soils.
FAU - Chu, Haena
AU  - Chu H
AD  - Western Seoul Center, Korea Basic Science Institute, Seoul 03759, Republic of 
      Korea.
FAU - Jo, Jungmin
AU  - Jo J
AD  - Department of Environmental Science and Engineering, Ewha Womans University, 
      Seoul 03760, Republic of Korea.
FAU - Son, Younggyu
AU  - Son Y
AD  - Department of Environmental Engineering, Kumoh National Institute of Technology, 
      Gumi 39177, Republic of Korea.
AD  - Department of Energy Engineering Convergence, Kumoh National Institute of 
      Technology, Gumi 39177, Republic of Korea.
FAU - Lee, Ji Yi
AU  - Lee JY
AUID- ORCID: 0000-0001-9386-2133
AD  - Department of Environmental Science and Engineering, Ewha Womans University, 
      Seoul 03760, Republic of Korea.
FAU - Ahn, Yun Gyong
AU  - Ahn YG
AUID- ORCID: 0000-0003-4256-3824
AD  - Western Seoul Center, Korea Basic Science Institute, Seoul 03759, Republic of 
      Korea.
LA  - eng
GR  - 2021002470001/Ministry of Environment/
GR  - C380200/Korea Basic Science Institute/
PT  - Journal Article
DEP - 20230828
PL  - Switzerland
TA  - Toxics
JT  - Toxics
JID - 101639637
PMC - PMC10536111
OTO - NOTNLM
OT  - dioxin-like polychlorinated biphenyls (dl-PCBs)
OT  - gas chromatography with triple quadrupole mass spectrometry (GC-QqQ-MS/MS)
OT  - one-step cleanup
OT  - persistent organic pollutants (POPs)
OT  - polychlorodibenzo-p-dioxins (PCDDs)
OT  - polychlorodibenzofurans (PCDFs)
OT  - soils
COIS- The authors declare no conflict of interest.
EDAT- 2023/09/27 12:42
MHDA- 2023/09/27 12:43
PMCR- 2023/08/28
CRDT- 2023/09/27 11:33
PHST- 2023/07/19 00:00 [received]
PHST- 2023/08/16 00:00 [revised]
PHST- 2023/08/24 00:00 [accepted]
PHST- 2023/09/27 12:43 [medline]
PHST- 2023/09/27 12:42 [pubmed]
PHST- 2023/09/27 11:33 [entrez]
PHST- 2023/08/28 00:00 [pmc-release]
AID - toxics11090738 [pii]
AID - toxics-11-00738 [pii]
AID - 10.3390/toxics11090738 [doi]
PST - epublish
SO  - Toxics. 2023 Aug 28;11(9):738. doi: 10.3390/toxics11090738.