PMID- 37761246
OWN - NLM
STAT- Publisher
LR  - 20231003
IS  - 2075-4418 (Print)
IS  - 2075-4418 (Electronic)
IS  - 2075-4418 (Linking)
VI  - 13
IP  - 18
DP  - 2023 Sep 8
TI  - Peripheral Interventional Strategy Assessment (PISA) for Diabetic Foot Ulcer 
      Revascularization: Preliminary Outcomes of a Multidisciplinary Pilot Study.
LID - 10.3390/diagnostics13182879 [doi]
LID - 2879
AB  - BACKGROUND: Digital subtraction angiography (DSA) still represents the gold 
      standard for anatomical arterial mapping and revascularization decision-making in 
      patients with chronic limb-threatening ischemia (CLTI), although DUS (Doppler 
      Ultrasound) remains a primary non-invasive examination tool. The Global Vascular 
      Guidelines established the importance of preoperative arterial mapping to 
      guarantee an adequate in-line flow to the foot. The aim of this study was to 
      evaluate the accuracy of DUS in guiding therapeutic vascular treatments on the 
      basis of Global Vascular Guidelines without the need of a second-level 
      examination. METHODS: Between January 2022 and June 2022, all consecutive 
      patients with CLTI to be revascularized underwent clinical examination and DUS 
      without further diagnostic examinations. Primary outcomes assessed were technical 
      success, and 30-day mortality. Secondary outcomes were 1-year amputation free 
      survival, and time between evaluation and revascularization. RESULTS: Sixty-eight 
      patients with a mean age of 73.6 +/- 8.5 years underwent lower limb 
      revascularization. Technical success was 100%, and the 30-day mortality rate was 
      2.9%. Mean time between evaluation and revascularization was 29 +/- 17 days. 
      One-year amputation free survival was 97.1%. CONCLUSIONS: DUS without further 
      diagnostic examinations can accurately assess the status of the vascular tree and 
      foot runoff, providing enough information about target vessels to guide 
      revascularization strategies.
FAU - Berchiolli, Raffaella
AU  - Berchiolli R
AD  - Vascular Surgery Unit, Department of Translational Research and New Technologies 
      in Medicine and Surgery, University of Pisa, 56126 Pisa, Italy.
FAU - Bertagna, Giulia
AU  - Bertagna G
AUID- ORCID: 0000-0003-1363-489X
AD  - Vascular Surgery Unit, Department of Translational Research and New Technologies 
      in Medicine and Surgery, University of Pisa, 56126 Pisa, Italy.
FAU - Adami, Daniele
AU  - Adami D
AD  - Vascular Surgery Unit, Department of Translational Research and New Technologies 
      in Medicine and Surgery, University of Pisa, 56126 Pisa, Italy.
FAU - Piaggesi, Alberto
AU  - Piaggesi A
AD  - Diabetic Foot Section, Department of Medicine, University of Pisa, 56126 Pisa, 
      Italy.
FAU - Iacopi, Elisabetta
AU  - Iacopi E
AD  - Diabetic Foot Section, Department of Medicine, University of Pisa, 56126 Pisa, 
      Italy.
FAU - Giangreco, Francesco
AU  - Giangreco F
AD  - Diabetic Foot Section, Department of Medicine, University of Pisa, 56126 Pisa, 
      Italy.
FAU - Torri, Lorenzo
AU  - Torri L
AUID- ORCID: 0000-0002-1587-2763
AD  - Vascular Surgery Unit, Department of Translational Research and New Technologies 
      in Medicine and Surgery, University of Pisa, 56126 Pisa, Italy.
FAU - Troisi, Nicola
AU  - Troisi N
AUID- ORCID: 0000-0002-8779-9120
AD  - Vascular Surgery Unit, Department of Translational Research and New Technologies 
      in Medicine and Surgery, University of Pisa, 56126 Pisa, Italy.
LA  - eng
PT  - Journal Article
DEP - 20230908
PL  - Switzerland
TA  - Diagnostics (Basel)
JT  - Diagnostics (Basel, Switzerland)
JID - 101658402
PMC - PMC10528535
OTO - NOTNLM
OT  - chronic limb-threatening ischemia
OT  - duplex ultrasonography
OT  - lower limb revascularization
COIS- The authors declare no conflict of interest.
EDAT- 2023/09/28 06:43
MHDA- 2023/09/28 06:43
PMCR- 2023/09/08
CRDT- 2023/09/28 01:11
PHST- 2023/07/27 00:00 [received]
PHST- 2023/08/28 00:00 [revised]
PHST- 2023/09/07 00:00 [accepted]
PHST- 2023/09/28 06:43 [medline]
PHST- 2023/09/28 06:43 [pubmed]
PHST- 2023/09/28 01:11 [entrez]
PHST- 2023/09/08 00:00 [pmc-release]
AID - diagnostics13182879 [pii]
AID - diagnostics-13-02879 [pii]
AID - 10.3390/diagnostics13182879 [doi]
PST - epublish
SO  - Diagnostics (Basel). 2023 Sep 8;13(18):2879. doi: 10.3390/diagnostics13182879.