PMID- 37762771
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20231003
IS  - 2077-0383 (Print)
IS  - 2077-0383 (Electronic)
IS  - 2077-0383 (Linking)
VI  - 12
IP  - 18
DP  - 2023 Sep 7
TI  - Minimal Clinically Important Difference (MCID) in the Functional Status Measures 
      in Patients with Stroke: Inverse Probability Treatment Weighting.
LID - 10.3390/jcm12185828 [doi]
LID - 5828
AB  - This study proposed to evaluate the temporal trend, define the minimal clinically 
      important difference (MCID) for five functional status measures, and identify 
      risk factors for reaching deterioration in the MCID. This prospective cohort 
      study analyzed 680 patients with ischemic stroke and 151 patients with 
      hemorrhagic stroke at six hospitals between April 2015 and October 2021. All 
      patients completed the functional status measures before rehabilitation 
      (baseline), and at the 12th week and 2nd year after rehabilitation. Patients in 
      the post-acute care (PAC) group exhibited significantly larger improvements for 
      the functional status measures compared to those in the non-PAC group (p < 0.05). 
      Patients with hemorrhagic stroke also displayed larger improvements in the 
      functional status measures when compared to patients with ischemic stroke. 
      Furthermore, the improvement in MCID ranged from 0.01 to 16.18 points when 
      comparing baseline and the 12th week after rehabilitation, but the deterioration 
      in MCID ranged from 0.38 to 16.12 points. Simultaneously, assessing the baseline 
      and the second year after rehabilitation, the improvement in MCID ranged from 
      0.01 to 18.43 points, but the deterioration in MCID ranged from 0.68 to 17.26 
      points. Additionally, the PAC program, age, education level, body mass index, 
      smoking, readmission within 30 days, baseline functional status score, use of 
      Foley catheter and nasogastric tube, as well as a history of previous stroke are 
      significantly associated with achieving deterioration in MCID (p < 0.05). These 
      findings suggest that if the mean change scores of the functional status measures 
      have reached the thresholds, the change scores can be perceived by patients as 
      clinically important.
FAU - Chang, Yu-Chien
AU  - Chang YC
AD  - Division of Neurology, Department of Internal Medicine, Yuan's General Hospital, 
      Kaohsiung 80249, Taiwan.
FAU - Lin, Hsiu-Fen
AU  - Lin HF
AD  - Department of Neurology, Kaohsiung Medical University Hospital, Kaohsiung 80756, 
      Taiwan.
AD  - Department of Neurology, Kaohsiung Medical University, Kaohsiung 80708, Taiwan.
FAU - Chen, Yu-Fu
AU  - Chen YF
AD  - Department of Clinical Education & Research, Yuan's General Hospital, Kaohsiung 
      80249, Taiwan.
FAU - Chen, Hong-Yaw
AU  - Chen HY
AD  - Superintendent and Division of Digestive Surgery, Department of Surgery, Yuan's 
      General Hospital, Kaohsiung 80249, Taiwan.
FAU - Shiu, Yu-Tsz
AU  - Shiu YT
AD  - Department of Healthcare Administration and Medical Informatics, Kaohsiung 
      Medical University, Kaohsiung 80708, Taiwan.
FAU - Shi, Hon-Yi
AU  - Shi HY
AUID- ORCID: 0000-0003-4700-0190
AD  - Department of Healthcare Administration and Medical Informatics, Kaohsiung 
      Medical University, Kaohsiung 80708, Taiwan.
AD  - Department of Business Management, National Sun Yat-sen University, Kaohsiung 
      80424, Taiwan.
AD  - Department of Medical Research, Kaohsiung Medical University Hospital, Kaohsiung 
      80756, Taiwan.
AD  - Department of Medical Research, China Medical University Hospital, China Medical 
      University, Taichung 40402, Taiwan.
LA  - eng
GR  - YUAN-IACR-22-05 or ST110003/Yuan's General Hospital/
GR  - KMU-DK(A)112009/Kaohsiung Medical University/
GR  - MOST 108-2410-H-037-006-SS3 & 111-2410-H-037-002-MY3/Ministry of Science and 
      Technology/
PT  - Journal Article
DEP - 20230907
PL  - Switzerland
TA  - J Clin Med
JT  - Journal of clinical medicine
JID - 101606588
PMC - PMC10532241
OTO - NOTNLM
OT  - deterioration
OT  - hemorrhagic stroke
OT  - ischemic stroke
OT  - minimal clinically important difference
OT  - post-acute care
COIS- The authors declare no conflict of interest.
EDAT- 2023/09/28 06:42
MHDA- 2023/09/28 06:43
PMCR- 2023/09/07
CRDT- 2023/09/28 01:22
PHST- 2023/07/28 00:00 [received]
PHST- 2023/08/16 00:00 [revised]
PHST- 2023/08/24 00:00 [accepted]
PHST- 2023/09/28 06:43 [medline]
PHST- 2023/09/28 06:42 [pubmed]
PHST- 2023/09/28 01:22 [entrez]
PHST- 2023/09/07 00:00 [pmc-release]
AID - jcm12185828 [pii]
AID - jcm-12-05828 [pii]
AID - 10.3390/jcm12185828 [doi]
PST - epublish
SO  - J Clin Med. 2023 Sep 7;12(18):5828. doi: 10.3390/jcm12185828.