PMID- 37764676 OWN - NLM STAT- MEDLINE DCOM- 20230929 LR - 20231003 IS - 2072-6643 (Electronic) IS - 2072-6643 (Linking) VI - 15 IP - 18 DP - 2023 Sep 7 TI - Association of Possible Sarcopenia or Sarcopenia with Body Composition, Nutritional Intakes, Serum Vitamin D Levels, and Physical Activity among Patients with Type 2 Diabetes Mellitus in Taiwan. LID - 10.3390/nu15183892 [doi] LID - 3892 AB - This study estimates the association between sarcopenia and blood biochemical parameters, nutritional intake, anthropometric measurements, physical performance, and physical activity in patients with type 2 diabetes mellitus (T2DM). Participants were recruited from a primary care clinic in Kaohsiung City. According to the diagnosis criteria of the Asian Working Group for Sarcopenia (AWGS) in 2019, 110 patients with T2DM (aged 50-80 years) were divided into three groups: non-sarcopenia (n = 38), possible sarcopenia (n = 31), and sarcopenia (n = 41). Blood samples were collected, and nutritional intake was evaluated by a registered dietitian. A food frequency questionnaire and a Godin leisure-time exercise questionnaire were used to assess their daily vitamin D intake and physical activity. There were significant differences in age, serum vitamin D levels, nutritional intake, anthropometric measurements, and physical performance between the three groups. In elderly patients with T2DM, reduced serum 25-hydroxyvitamin D [25(OH)D] levels and daily energy intake were significantly associated with possible sarcopenia. Age, lower BMI, reduced serum 25(OH)D, and reduced dietary protein and vitamin D intake were significantly associated with sarcopenia. These findings may serve as the basis for intervention trials to reduce the prevalence of sarcopenia. FAU - Hsu, Yu-Ting AU - Hsu YT AD - Nutrition and Food Service Department, Kaohsiung Veterans General Hospital, No. 386, Dazhong 1st Rd., Zuoying Dist., Kaohsiung City 81362, Taiwan. AD - Department of Sports Medicine, College of Medicine, Kaohsiung Medical University, No. 100, Shih-Chuan 1st Road, Sanmin Dist., Kaohsiung City 80708, Taiwan. FAU - Lin, Jian-Yu AU - Lin JY AD - Nutrition and Food Service Department, Kaohsiung Veterans General Hospital, No. 386, Dazhong 1st Rd., Zuoying Dist., Kaohsiung City 81362, Taiwan. AD - Department of Sports Medicine, College of Medicine, Kaohsiung Medical University, No. 100, Shih-Chuan 1st Road, Sanmin Dist., Kaohsiung City 80708, Taiwan. FAU - Lin, Chien-Ju AU - Lin CJ AD - School of Pharmacy, College of Pharmacy, Kaohsiung Medical University, No. 100, Shih-Chuan 1st Road, Sanmin Dist., Kaohsiung City 80708, Taiwan. FAU - Lee, Yau-Jiunn AU - Lee YJ AD - Lee's Endocrinology Clinic, No. 396, Guangdong Road, Pingtung City 90028, Taiwan. FAU - Chang, Wen-Hsin AU - Chang WH AUID- ORCID: 0000-0003-3429-9920 AD - Department of Sports Medicine, College of Medicine, Kaohsiung Medical University, No. 100, Shih-Chuan 1st Road, Sanmin Dist., Kaohsiung City 80708, Taiwan. LA - eng GR - KSVGH110-036/Kaohsiung Veterans General Hospital/ PT - Journal Article DEP - 20230907 PL - Switzerland TA - Nutrients JT - Nutrients JID - 101521595 RN - 1406-16-2 (Vitamin D) SB - IM MH - Aged MH - Humans MH - *Diabetes Mellitus, Type 2/complications MH - Taiwan/epidemiology MH - *Sarcopenia/epidemiology/etiology MH - Body Composition MH - Eating MH - Exercise MH - Vitamin D PMC - PMC10535053 OTO - NOTNLM OT - nutritional intake OT - physical performance OT - sarcopenia OT - serum vitamin D levels OT - type 2 diabetes mellitus COIS- The authors declare no conflict of interest. EDAT- 2023/09/28 06:43 MHDA- 2023/09/29 06:43 PMCR- 2023/09/07 CRDT- 2023/09/28 01:35 PHST- 2023/07/11 00:00 [received] PHST- 2023/08/26 00:00 [revised] PHST- 2023/09/04 00:00 [accepted] PHST- 2023/09/29 06:43 [medline] PHST- 2023/09/28 06:43 [pubmed] PHST- 2023/09/28 01:35 [entrez] PHST- 2023/09/07 00:00 [pmc-release] AID - nu15183892 [pii] AID - nutrients-15-03892 [pii] AID - 10.3390/nu15183892 [doi] PST - epublish SO - Nutrients. 2023 Sep 7;15(18):3892. doi: 10.3390/nu15183892.