PMID- 37765691 OWN - NLM STAT- PubMed-not-MEDLINE LR - 20240210 IS - 2073-4360 (Electronic) IS - 2073-4360 (Linking) VI - 15 IP - 18 DP - 2023 Sep 20 TI - Electrospun PVA Fibers for Drug Delivery: A Review. LID - 10.3390/polym15183837 [doi] LID - 3837 AB - Innovation in biomedical science is always a field of interest for researchers. Drug delivery, being one of the key areas of biomedical science, has gained considerable significance. The utilization of simple yet effective techniques such as electrospinning has undergone significant development in the field of drug delivery. Various polymers such as PEG (polyethylene glycol), PLGA (Poly(lactic-co-glycolic acid)), PLA(Polylactic acid), and PCA (poly(methacrylate citric acid)) have been utilized to prepare electrospinning-based drug delivery systems (DDSs). Polyvinyl alcohol (PVA) has recently gained attention because of its biocompatibility, biodegradability, non-toxicity, and ideal mechanical properties as these are the key factors in developing DDSs. Moreover, it has shown promising results in developing DDSs individually and when combined with natural and synthetic polymers such as chitosan and polycaprolactone (PCL). Considering the outstanding properties of PVA, the aim of this review paper was therefore to summarize these recent advances by highlighting the potential of electrospun PVA for drug delivery systems. FAU - Zahra, Fatima T AU - Zahra FT AUID- ORCID: 0000-0003-4134-3002 AD - TIGER Institute, Tennessee State University, Nashville, TN 37209, USA. FAU - Quick, Quincy AU - Quick Q AD - Department of Biological Sciences, Tennessee State University, Nashville, TN 37209, USA. FAU - Mu, Richard AU - Mu R AD - TIGER Institute, Tennessee State University, Nashville, TN 37209, USA. LA - eng GR - U54 CA163072/CA/NCI NIH HHS/United States PT - Journal Article PT - Review DEP - 20230920 PL - Switzerland TA - Polymers (Basel) JT - Polymers JID - 101545357 PMC - PMC10536586 OTO - NOTNLM OT - drug delivery OT - electrospinning OT - nanofibers OT - polyvinyl alcohol (PVA) OT - tissue engineering OT - transdermal OT - wound dressing COIS- There are no conflict to declare. EDAT- 2023/09/28 06:42 MHDA- 2023/09/28 06:43 PMCR- 2023/09/20 CRDT- 2023/09/28 01:41 PHST- 2023/08/31 00:00 [received] PHST- 2023/09/14 00:00 [revised] PHST- 2023/09/16 00:00 [accepted] PHST- 2023/09/28 06:43 [medline] PHST- 2023/09/28 06:42 [pubmed] PHST- 2023/09/28 01:41 [entrez] PHST- 2023/09/20 00:00 [pmc-release] AID - polym15183837 [pii] AID - polymers-15-03837 [pii] AID - 10.3390/polym15183837 [doi] PST - epublish SO - Polymers (Basel). 2023 Sep 20;15(18):3837. doi: 10.3390/polym15183837.