PMID- 37772239
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20231003
IS  - 2168-8184 (Print)
IS  - 2168-8184 (Electronic)
IS  - 2168-8184 (Linking)
VI  - 15
IP  - 8
DP  - 2023 Aug
TI  - Frequency of Gastroparesis Symptoms in Patients With Type-2 Diabetes Mellitus at 
      a Tertiary Care Hospital in Pakistan.
PG  - e44236
LID - 10.7759/cureus.44236 [doi]
LID - e44236
AB  - Background Gastroparesis symptoms seem to affect many diabetes mellitus patients. 
      Pakistan has a high prevalence of diabetes, with an estimated 33 million people 
      living with the condition. This study aimed to investigate the frequency of 
      gastroparesis symptoms in patients with type-2 diabetes mellitus (T2DM). Methods 
      This cross-sectional study was conducted from April to May 2022 in the outpatient 
      Department of Medicine at the University College of Medicine and Dentistry, 
      Lahore, Pakistan. Patients of both genders aged between 18 and 75 years and 
      having T2DM were analysed. Data regarding demographic information, medical 
      history, BMI assessment, and symptoms related to gastroparesis, as measured by 
      the Gastroparesis Cardinal Symptoms Index (GCSI) were collected at the time of 
      enrolment. For gastroparesis, a diagnostic cutoff of >/=1.90 was considered as per 
      GCSI. Results Of a total of 148 T2DM patients, 85 (57.4%) were females. The mean 
      age was calculated to be 54.0+/-11.3 years, ranging between 23 and 75 years. There 
      were 134 (90.5%) patients who were using metformin. The most common symptom was 
      fullness, reported by 66 (44.6%), while nausea, bloating, early satiety, 
      retching, and vomiting were noted in 61 (41.2%), 59 (39.9%), 55 (37.2%), 39 
      (26.4%), and 22 (14.9%) patients, respectively. The frequency of gastroparesis 
      was found in 17 (11.5%) T2DM patients. Stratification of gastroparesis revealed a 
      significant association with female gender (82.4% vs. 54.2%, p=0.0272). 
      Conclusion The study found a high frequency of gastroparesis symptoms in patients 
      with T2DM. Nausea and bloating were the most commonly reported symptoms, while 
      vomiting was the least common. The prevalence of gastroparesis was significantly 
      higher in the female gender.
CI  - Copyright (c) 2023, Asif et al.
FAU - Asif, Mohammad Shahzad
AU  - Asif MS
AD  - Medicine, University College of Medicine and Dentistry, Lahore, PAK.
FAU - Khan, Muhammad Khubaib Gul
AU  - Khan MKG
AD  - Medicine, University College of Medicine and Dentistry, Lahore, PAK.
FAU - Nabeel, Muhammad Asad
AU  - Nabeel MA
AD  - Medicine, University College of Medicine and Dentistry, Lahore, PAK.
FAU - Ashfaq, Tabin
AU  - Ashfaq T
AD  - Medicine, University College of Medicine and Dentistry, Lahore, PAK.
FAU - Nasir, Areeqa
AU  - Nasir A
AD  - Medicine, University College of Medicine and Dentistry, Lahore, PAK.
FAU - Abdullah, Rai Muhammad
AU  - Abdullah RM
AD  - Medicine, University College of Medicine and Dentistry, Lahore, PAK.
FAU - Kareem, Muhammad Ahmad Faraz
AU  - Kareem MAF
AD  - Medicine, University College of Medicine and Dentistry, Lahore, PAK.
LA  - eng
PT  - Journal Article
DEP - 20230828
PL  - United States
TA  - Cureus
JT  - Cureus
JID - 101596737
PMC - PMC10523834
OTO - NOTNLM
OT  - bloating
OT  - gastroparesis
OT  - nausea
OT  - type-2 diabetes mellitus
OT  - vomiting
COIS- The authors have declared that no competing interests exist.
EDAT- 2023/09/29 06:44
MHDA- 2023/09/29 06:45
PMCR- 2023/08/28
CRDT- 2023/09/29 04:04
PHST- 2023/08/27 00:00 [accepted]
PHST- 2023/09/29 06:45 [medline]
PHST- 2023/09/29 06:44 [pubmed]
PHST- 2023/09/29 04:04 [entrez]
PHST- 2023/08/28 00:00 [pmc-release]
AID - 10.7759/cureus.44236 [doi]
PST - epublish
SO  - Cureus. 2023 Aug 28;15(8):e44236. doi: 10.7759/cureus.44236. eCollection 2023 
      Aug.