PMID- 37772447 OWN - NLM STAT- Publisher LR - 20231101 IS - 1443-1661 (Electronic) IS - 0915-5635 (Linking) DP - 2023 Sep 29 TI - PERcutaneous transhepatic CHOLangioscopy using a new single-operator short cholangioscope (PERCHOL): European feasibility study. LID - 10.1111/den.14697 [doi] AB - OBJECTIVES: A new short device for percutaneous endoscopic cholangioscopy was recently developed. However, feasibility and safety has not yet been evaluated. The aim of this study was to assess clinical success, technical success, and adverse events (AEs). METHODS: This observational multicenter retrospective study included all patients who underwent percutaneous cholangioscopy using a short cholangioscope between 2020 and 2022. The clinical success, defined as the complete duct clearance or obtaining at least one cholangioscopy-guided biopsy, was assessed. The histopathological accuracy, technical success, and the AE rate were also evaluated. RESULTS: Fifty-one patients (60 +/- 15 years, 45.1% male) were included. The majority of patients had altered anatomy (n = 40, 78.4%), and biliary stones (n = 34, 66.7%) was the commonest indication. The technique was predominantly wire-guided (n = 44, 86.3%) through a percutaneous sheath (n = 36, 70.6%) following a median interval of 8.5 days from percutaneous drainage. Cholangioscopy-guided electrohydraulic lithotripsy was performed in 29 cases (56.9%), combined with a retrieval basket in eight cases (27.6%). The clinical success was 96.6%, requiring a median of one session (range 1-3). Seventeen patients (33.3%) underwent cholangioscopy-guided biopsies. There were four (7.8%) cholangioscopy-related AEs (cholangitis and peritonitis). Overall, the technical success and AE rates were 100% and 19.6%, respectively, in a median follow-up of 7 months. CONCLUSION: Percutaneous endoscopic cholangioscopy with a new short device is effective and safe, requiring a low number of sessions to achieve duct clearance or accurate histopathological diagnosis. CI - (c) 2023 The Authors. Digestive Endoscopy published by John Wiley & Sons Australia, Ltd on behalf of Japan Gastroenterological Endoscopy Society. FAU - Perez-Cuadrado-Robles, Enrique AU - Perez-Cuadrado-Robles E AUID- ORCID: 0000-0001-8254-7453 AD - Department of Gastroenterology, Georges-Pompidou European Hospital, APHP.Centre, Paris, France. AD - University of Paris-Cite, Paris, France. FAU - Phillpotts, Simon AU - Phillpotts S AD - Department of Gastroenterology, University College London Hospitals, London, UK. FAU - Bronswijk, Michiel AU - Bronswijk M AUID- ORCID: 0000-0003-2039-5022 AD - Department of Gastroenterology and Hepatology, University Hospital Gasthuisberg, University of Leuven, Leuven, Belgium. AD - Department of Gastroenterology and Hepatology, Imelda Hospital, Bonheiden, Belgium. FAU - Conrad, Claudio Cim AU - Conrad CC AD - Department of Interdisciplinary Endoscopy, Medical Department 1, University Hospital Schleswig-Holstein, Campus Kiel, Kiel, Germany. FAU - Binda, Cecilia AU - Binda C AUID- ORCID: 0000-0003-1148-9684 AD - Gastroenterology and Digestive Endoscopy Unit, Forli-Cesena Hospitals, AUSL Romagna, Ravenna, Italy. FAU - Monino, Laurent AU - Monino L AUID- ORCID: 0000-0001-7922-0396 AD - Department of Gastroenterology, Cliniques Universitaires St. Luc, Universite catholique de Louvain, Brussels, Belgium. FAU - Basiliya, Kirill AU - Basiliya K AD - Department of Gastroenterology, University College London Hospitals, London, UK. FAU - Hollenbach, Marcus AU - Hollenbach M AUID- ORCID: 0000-0002-2654-3164 AD - Division of Gastroenterology, Medical Department II, University of Leipzig Medical Center, Leipzig, Germany. FAU - Papaefthymiou, Apostolis AU - Papaefthymiou A AD - Department of Gastroenterology, University College London Hospitals, London, UK. FAU - Alric, Hadrien AU - Alric H AD - Department of Gastroenterology, Georges-Pompidou European Hospital, APHP.Centre, Paris, France. AD - University of Paris-Cite, Paris, France. FAU - Queneherve, Lucille AU - Queneherve L AUID- ORCID: 0000-0001-5443-2579 AD - Gastroenterology Department, University and Regional Hospital Centre Brest, Brest, France. FAU - Di Gaeta, Alessandro AU - Di Gaeta A AD - Department of Interventional Radiology, Georges-Pompidou European Hospital, Paris, France. FAU - Pioche, Mathieu AU - Pioche M AD - Gastroenterology and Endoscopy Unit, Edouard Herriot Hospital, Hospices Civils de Lyon, Lyon, France. FAU - Khani, Aria AU - Khani A AD - Department of Gastroenterology, Royal Free Hospital, London, UK. FAU - Lorenzo, Diane AU - Lorenzo D AD - Digestive Endoscopy Department, Beaujon Hospital, APHP.Nord, Clichy, France. FAU - Moreels, Tom G AU - Moreels TG AD - Department of Gastroenterology, Cliniques Universitaires St. Luc, Universite catholique de Louvain, Brussels, Belgium. FAU - Rahmi, Gabriel AU - Rahmi G AD - Department of Gastroenterology, Georges-Pompidou European Hospital, APHP.Centre, Paris, France. AD - University of Paris-Cite, Paris, France. FAU - Boeken, Tom AU - Boeken T AD - University of Paris-Cite, Paris, France. AD - Department of Interventional Radiology, Georges-Pompidou European Hospital, Paris, France. FAU - Fabbri, Carlo AU - Fabbri C AD - Gastroenterology and Digestive Endoscopy Unit, Forli-Cesena Hospitals, AUSL Romagna, Ravenna, Italy. FAU - Prat, Frederic AU - Prat F AD - Digestive Endoscopy Department, Beaujon Hospital, APHP.Nord, Clichy, France. FAU - Laleman, Wim AU - Laleman W AD - Department of Gastroenterology and Hepatology, University Hospital Gasthuisberg, University of Leuven, Leuven, Belgium. AD - Medizinische Klinik B, Universitatsklinikum Munster, Munster University, Munster, Germany. FAU - Cellier, Christophe AU - Cellier C AD - Department of Gastroenterology, Georges-Pompidou European Hospital, APHP.Centre, Paris, France. AD - University of Paris-Cite, Paris, France. FAU - Van der Merwe, Schalk AU - Van der Merwe S AD - Department of Gastroenterology and Hepatology, University Hospital Gasthuisberg, University of Leuven, Leuven, Belgium. FAU - Webster, George AU - Webster G AD - Department of Gastroenterology, University College London Hospitals, London, UK. FAU - Ellrichmann, Mark AU - Ellrichmann M AD - Department of Interdisciplinary Endoscopy, Medical Department 1, University Hospital Schleswig-Holstein, Campus Kiel, Kiel, Germany. LA - eng PT - Journal Article DEP - 20230929 PL - Australia TA - Dig Endosc JT - Digestive endoscopy : official journal of the Japan Gastroenterological Endoscopy Society JID - 9101419 SB - IM OTO - NOTNLM OT - PTBD OT - biliary stone OT - biliary stricture OT - cholangioscopy EDAT- 2023/09/29 06:44 MHDA- 2023/09/29 06:44 CRDT- 2023/09/29 05:30 PHST- 2023/06/04 00:00 [received] PHST- 2023/09/27 00:00 [accepted] PHST- 2023/09/29 06:44 [pubmed] PHST- 2023/09/29 06:44 [medline] PHST- 2023/09/29 05:30 [entrez] AID - 10.1111/den.14697 [doi] PST - aheadofprint SO - Dig Endosc. 2023 Sep 29. doi: 10.1111/den.14697.