PMID- 37773304
OWN - NLM
STAT- MEDLINE
DCOM- 20231026
LR  - 20231110
IS  - 2210-7711 (Electronic)
IS  - 2210-7703 (Print)
VI  - 45
IP  - 5
DP  - 2023 Oct
TI  - A systematic review of quantitative studies exploring staff views on 
      antipsychotic use in residents with dementia in care homes.
PG  - 1050-1061
LID - 10.1007/s11096-023-01645-2 [doi]
AB  - BACKGROUND: Despite significant warnings of adverse effects, antipsychotics 
      continue to be prescribed for managing the behavioural and psychological symptoms 
      of dementia (BPSD) in care homes. Information provided by staff working within 
      care homes is a factor that can influence prescribing decisions in residents with 
      BPSD. AIM: The review aimed to capture care home staff views towards 
      antipsychotics for residents with BPSD and separately analyse tools utilized in 
      the studies, mapping them onto the theory of planned behaviour (TPB). METHOD: A 
      comprehensive literature search published in ten databases was conducted between 
      May and July 2020 and updated in July 2021. Studies published in full with no 
      date restriction were included and quality assessed using CROSS checklist. A 
      thematic framework approach was applied to extract data and study tools 
      which were then mapped onto the TPB. RESULTS: Fourteen studies (2059 
      participants) were included. Findings identified four overarching themes: 
      attitudes toward antipsychotics (e.g. antipsychotics as an appropriate strategy 
      and effectiveness); barriers to deprescribing (e.g. lower staff education, lack 
      of resources and time, poor medication reviews); measures implemented (e.g. 
      nonpharmacological interventions, medication reviews); and perceived needs of 
      staff (e.g. need for training, financial or clinical support). Identified tools 
      addressed seven but not all components of TPB namely, behavioural, normative and 
      control beliefs, attitude, perceived behavioural control, intention and 
      behaviour. CONCLUSION: The positive attitudes toward antipsychotics, the 
      identified barriers to deprescribing and the existing tools not addressing all 
      components of the TPB provide the impetus for further research.
CI  - (c) 2023. The Author(s).
FAU - Raza, Amna
AU  - Raza A
AUID- ORCID: 0000-0001-9317-8745
AD  - Reading School of Pharmacy, University of Reading, Reading, UK. 
      a.raza@pgr.reading.ac.uk.
FAU - Piekarz, Hannah
AU  - Piekarz H
AUID- ORCID: 0000-0002-2706-1677
AD  - Reading School of Pharmacy, University of Reading, Reading, UK.
FAU - Jawad, Sundus
AU  - Jawad S
AD  - NHS Frimley, King Edward VII Hospital, Windsor, UK.
FAU - Langran, Tim
AU  - Langran T
AD  - NHS Frimley, King Edward VII Hospital, Windsor, UK.
FAU - Donyai, Parastou
AU  - Donyai P
AUID- ORCID: 0000-0001-5403-6170
AD  - Department of Pharmacy and Forensic Science, King's College London, London, UK.
LA  - eng
PT  - Journal Article
PT  - Review
PT  - Systematic Review
DEP - 20230929
PL  - Netherlands
TA  - Int J Clin Pharm
JT  - International journal of clinical pharmacy
JID - 101554912
RN  - 0 (Antipsychotic Agents)
SB  - IM
MH  - Humans
MH  - Nursing Homes
MH  - *Antipsychotic Agents/adverse effects
MH  - *Dementia/drug therapy/epidemiology/chemically induced
MH  - Attitude of Health Personnel
PMC - PMC10600045
OTO - NOTNLM
OT  - Antipsychotic
OT  - Care homes
OT  - Dementia
OT  - Staff
OT  - Surveys and questionnaires
OT  - Systematic review
COIS- The authors have no relevant financial or non-financial interests to disclose.
EDAT- 2023/09/29 18:42
MHDA- 2023/10/26 06:42
PMCR- 2023/09/29
CRDT- 2023/09/29 14:43
PHST- 2023/06/20 00:00 [received]
PHST- 2023/08/26 00:00 [accepted]
PHST- 2023/10/26 06:42 [medline]
PHST- 2023/09/29 18:42 [pubmed]
PHST- 2023/09/29 14:43 [entrez]
PHST- 2023/09/29 00:00 [pmc-release]
AID - 10.1007/s11096-023-01645-2 [pii]
AID - 1645 [pii]
AID - 10.1007/s11096-023-01645-2 [doi]
PST - ppublish
SO  - Int J Clin Pharm. 2023 Oct;45(5):1050-1061. doi: 10.1007/s11096-023-01645-2. Epub 
      2023 Sep 29.