PMID- 37774898
OWN - NLM
STAT- MEDLINE
DCOM- 20231216
LR  - 20240131
IS  - 1535-6280 (Electronic)
IS  - 0146-2806 (Linking)
VI  - 49
IP  - 1 Pt C
DP  - 2024 Jan
TI  - Right to Left Cardiac Power Output- New Prognosticator in STEMI Patients With 
      Cardiogenic Shock (R-Shock).
PG  - 102089
LID - S0146-2806(23)00506-6 [pii]
LID - 10.1016/j.cpcardiol.2023.102089 [doi]
AB  - ST elevation myocardial infarction (STEMI) is a leading cause of cardiogenic 
      shock (CS) and carries substantial mortality. Cardiac power output (CPO) is the 
      strongest predictor of clinical outcome in CS, and worse outcomes result from 
      concomitant right and left ventricular failure. Right ventricular performance is 
      calculated using right sided CPO. Our aim was to measure the right sided CPO and 
      compute their ratio to predict in-hospital mortality in STEMI patients with 
      cardiogenic shock. This was a retrospective observational study of consecutive 
      STEMI patients with CS that developed within the first 24hours of admission 
      requiring left and right cardiac catheterization at a large tertiary care center 
      from January 2014-December 2018. One hundred sixty-four patients identified with 
      STEMI; 46% (75) excluded due to incomplete data. 88 remaining patients, 52.8% 
      (47) developed CS. 98.9% within 24 hours. Mean left & right CPO 0.62 (SD 0.3) and 
      0.22 (SD 0.13), PAPi score 1.81. Logistic regression analysis indicated odds 
      ratio of in-hospital mortality lower for low left CPO, high right CPO and low 
      ratio of left to right CPO (95% CI; 0.69, 0.34, 1.20; 1.38, 0.87, 2.20; 0.52, 
      0.28, 1.00 respectively). This is the first study to assess right sided CPO and 
      ratio of right and left side CPO and mortality. Our study indicates that there is 
      trend towards higher in-hospital mortality in patients with high right sided CPO 
      and lower ratio of left to right CPO. The exploratory results of this study need 
      to be confirmed in a larger population.
CI  - Copyright (c) 2023. Published by Elsevier Inc.
FAU - Sundaram, Arvind Kalyan
AU  - Sundaram AK
AD  - Baystate Medical Center, UMASS-Chan Medical School.
FAU - Gobeil, Kyle
AU  - Gobeil K
AD  - Yale University School of Medicine, New Haven, CT.
FAU - Pundlik, Shayal
AU  - Pundlik S
AD  - Baystate Medical Center, UMASS-Chan Medical School.
FAU - Capatina, Alina
AU  - Capatina A
AD  - Baystate Medical Center, UMASS-Chan Medical School.
FAU - Scarnici, Annette
AU  - Scarnici A
AD  - Baystate Medical Center, UMASS-Chan Medical School.
FAU - Natarajan, Poorna Pushkala
AU  - Natarajan PP
AD  - Apollo Hospital, India.
FAU - Kashef, Mohammad Amin
AU  - Kashef MA
AD  - Baystate Medical Center, UMASS-Chan Medical School.
FAU - Haider, Ali
AU  - Haider A
AD  - New York-Presbyterian Medical Group of Queens, NY.
FAU - Daoulah, Amin
AU  - Daoulah A
AD  - Department of Cardiovascular Medicine, King Faisal Specialist Hospital & Research 
      Center, Jeddah, Saudi Arabia.
FAU - St Marie, Peter
AU  - St Marie P
AD  - Baystate Medical Center, UMASS-Chan Medical School.
FAU - Lotfi, Amir
AU  - Lotfi A
AD  - Baystate Medical Center, UMASS-Chan Medical School. Electronic address: 
      amir.lotfi@baystatehealth.org.
LA  - eng
PT  - Journal Article
PT  - Review
DEP - 20230927
PL  - Netherlands
TA  - Curr Probl Cardiol
JT  - Current problems in cardiology
JID - 7701802
SB  - IM
MH  - Humans
MH  - Shock, Cardiogenic/diagnosis/etiology/therapy
MH  - *ST Elevation Myocardial Infarction/complications/diagnosis
MH  - Retrospective Studies
MH  - *Percutaneous Coronary Intervention/adverse effects
MH  - Treatment Outcome
MH  - Observational Studies as Topic
COIS- Declaration of Competing Interest The authors declare that they have no known 
      competing financial interests or personal relationships that could have appeared 
      to influence the work reported in this paper.
EDAT- 2023/09/30 09:42
MHDA- 2023/12/17 09:45
CRDT- 2023/09/29 19:15
PHST- 2023/09/12 00:00 [received]
PHST- 2023/09/12 00:00 [accepted]
PHST- 2023/12/17 09:45 [medline]
PHST- 2023/09/30 09:42 [pubmed]
PHST- 2023/09/29 19:15 [entrez]
AID - S0146-2806(23)00506-6 [pii]
AID - 10.1016/j.cpcardiol.2023.102089 [doi]
PST - ppublish
SO  - Curr Probl Cardiol. 2024 Jan;49(1 Pt C):102089. doi: 
      10.1016/j.cpcardiol.2023.102089. Epub 2023 Sep 27.