PMID- 37776076
OWN - NLM
STAT- MEDLINE
DCOM- 20231216
LR  - 20231216
IS  - 1365-2761 (Electronic)
IS  - 0140-7775 (Linking)
VI  - 47
IP  - 1
DP  - 2024 Jan
TI  - Effect of florfenicol on Piscirickettsia salmonis biofilm formed in materials 
      used in salmonid nets, nylon and high-density polyethylene.
PG  - e13862
LID - 10.1111/jfd.13862 [doi]
AB  - Piscirickettsiosis is the most prevalent bacterial disease affecting seawater 
      salmon in Chilean salmon industry. Antibiotic therapy is the first alternative to 
      counteract infections caused by Piscirickettsia salmonis. The presence of 
      bacterial biofilms on materials commonly used in salmon farming may be critical 
      for understanding the bacterial persistence in the environment. In the present 
      study, the CDC Biofilm Reactor(R) was used to investigate the effect of sub- and 
      over-MIC of florfenicol on both the pre-formed biofilm and the biofilm formation 
      by P. salmonis under the antibiotic stimuli on Nylon and high-density 
      polyethylene (HDPE) surfaces. This study demonstrated that FLO, at sub- and 
      over-MIC doses, decreases biofilm-embedded live bacteria in the P. salmonis 
      isolates evaluated. However, it was shown that in the P. salmonis Ps007 strain 
      the presence of sub-MIC of FLO reduced its biofilm formation on HDPE surfaces; 
      however, biofilm persists on Nylon surfaces. These results demonstrated that P. 
      salmonis isolates behave differently against FLO and also, depending on the 
      surface materials. Therefore, it remains a challenge to find an effective 
      strategy to control the biofilm formation of P. salmonis, and certainly other 
      marine pathogens that affect the sustainability of the Chilean salmon industry.
CI  - (c) 2023 John Wiley & Sons Ltd.
FAU - Oliver, Cristian
AU  - Oliver C
AUID- ORCID: 0000-0002-2266-6706
AD  - Laboratorio de Inmunologia y Estres de Organismos Acuaticos, Instituto de 
      Patologia Animal, Facultad de Ciencias Veterinarias, Universidad Austral de 
      Chile, Valdivia, Chile.
FAU - Ruiz, Pamela
AU  - Ruiz P
AUID- ORCID: 0000-0003-0093-4439
AD  - Laboratorio de Biopeliculas y Microbiologia Ambiental, Centro de Biotecnologia, 
      Universidad de Concepcion, Concepcion, Chile.
AD  - Departamento de Ciencias Biologicas, Facultad de Ciencias de la Vida, Universidad 
      Andres Bello, Talcahuano, Chile.
FAU - Vidal, Jose Miguel
AU  - Vidal JM
AD  - Laboratorio de Biopeliculas y Microbiologia Ambiental, Centro de Biotecnologia, 
      Universidad de Concepcion, Concepcion, Chile.
AD  - Departamento de Investigacion y Desarrollo, Ecombio Limitada, Concepcion, Chile.
FAU - Carrasco, Carlos
AU  - Carrasco C
AD  - Laboratorio de Biopeliculas y Microbiologia Ambiental, Centro de Biotecnologia, 
      Universidad de Concepcion, Concepcion, Chile.
FAU - Escalona, Carla Estefania
AU  - Escalona CE
AD  - Laboratorio de Inmunologia y Estres de Organismos Acuaticos, Instituto de 
      Patologia Animal, Facultad de Ciencias Veterinarias, Universidad Austral de 
      Chile, Valdivia, Chile.
FAU - Barros, Javier
AU  - Barros J
AD  - Departamento de Investigacion y Desarrollo, Micbiotech Spa, Concepcion, Chile.
FAU - Sepulveda, Daniela
AU  - Sepulveda D
AD  - Laboratorio de Biopeliculas y Microbiologia Ambiental, Centro de Biotecnologia, 
      Universidad de Concepcion, Concepcion, Chile.
FAU - Urrutia, Homero
AU  - Urrutia H
AD  - Laboratorio de Biopeliculas y Microbiologia Ambiental, Centro de Biotecnologia, 
      Universidad de Concepcion, Concepcion, Chile.
AD  - Departamento de Microbiologia, Facultad de Ciencias Biologicas, Universidad de 
      Concepcion, Concepcion, Chile.
FAU - Romero, Alex
AU  - Romero A
AD  - Laboratorio de Inmunologia y Estres de Organismos Acuaticos, Instituto de 
      Patologia Animal, Facultad de Ciencias Veterinarias, Universidad Austral de 
      Chile, Valdivia, Chile.
AD  - Interdisciplinary Center for Aquaculture Research, (INCAR), Concepcion, Chile.
LA  - eng
GR  - Fondo de Financiamiento de Centros de Investigacion en Areas Prioritarias/
GR  - Fondo Nacional de Desarrollo Cientifico y Tecnologico/
PT  - Journal Article
DEP - 20230930
PL  - England
TA  - J Fish Dis
JT  - Journal of fish diseases
JID - 9881188
RN  - 9J97307Y1H (florfenicol)
RN  - 9002-88-4 (Polyethylene)
RN  - 0 (Nylons)
RN  - 0 (Anti-Bacterial Agents)
RN  - Piscirickettsia salmonis
SB  - IM
MH  - Animals
MH  - Polyethylene/pharmacology
MH  - Nylons/pharmacology
MH  - *Salmonidae
MH  - *Fish Diseases/drug therapy/prevention & control/microbiology
MH  - *Piscirickettsia
MH  - Anti-Bacterial Agents/pharmacology
MH  - Salmon
MH  - Biofilms
MH  - *Piscirickettsiaceae Infections/veterinary/microbiology
OTO - NOTNLM
OT  - Piscirickettsia salmonis
OT  - CDC biofilm reactor
OT  - SRS
OT  - biofilm
OT  - florfenicol
EDAT- 2023/09/30 09:42
MHDA- 2023/12/17 09:45
CRDT- 2023/09/30 03:34
PHST- 2023/08/29 00:00 [revised]
PHST- 2023/06/22 00:00 [received]
PHST- 2023/09/05 00:00 [accepted]
PHST- 2023/12/17 09:45 [medline]
PHST- 2023/09/30 09:42 [pubmed]
PHST- 2023/09/30 03:34 [entrez]
AID - 10.1111/jfd.13862 [doi]
PST - ppublish
SO  - J Fish Dis. 2024 Jan;47(1):e13862. doi: 10.1111/jfd.13862. Epub 2023 Sep 30.