PMID- 37780924
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20231003
IS  - 2050-0904 (Print)
IS  - 2050-0904 (Electronic)
IS  - 2050-0904 (Linking)
VI  - 11
IP  - 10
DP  - 2023 Oct
TI  - Presumed first episode of nonconvulsive status epilepticus as the cause of 
      postoperative disorder of consciousness following the completion of general 
      anesthesia: A case report.
PG  - e7988
LID - 10.1002/ccr3.7988 [doi]
LID - e7988
AB  - KEY CLINICAL MESSAGE: Disorder of consciousness can lead to irreversible sequelae 
      without proper intervention. Consequently, early diagnosis and treatment are of 
      paramount importance in patients with disorder of consciousness. ABSTRACT: 
      Disorder of consciousness (DOC) has various etiologies. Here, we report a case in 
      which DOC following general anesthesia was suspected as being due to the first 
      episode of nonconvulsive status epilepticus (NCSE). An elderly man in his 80s 
      underwent uneventful tumor resection surgery under general anesthesia for 
      extramammary Paget's disease. After the procedure, he regained consciousness 
      following anesthesia discontinuation and was extubated. Soon after extubation, 
      however, although his respiratory status remained stable, his level of 
      consciousness deteriorated to a Glasgow Coma Scale (GCS) score of E1V1M1. Head 
      computed tomography and magnetic resonance imaging scans indicated no abnormal 
      findings. Subsequently, involuntary movements were noted in his left upper limb. 
      Suspecting an epilepsy episode, diazepam was administered, leading to an 
      improvement in the level of consciousness (GCS: E4V5M6). Based on the improvement 
      in consciousness after diazepam administration, we strongly suspected NCSE.
CI  - (c) 2023 The Authors. Clinical Case Reports published by John Wiley & Sons Ltd.
FAU - Tsuzuki, Yumi
AU  - Tsuzuki Y
AD  - Department of Anesthesiology Tokyo Medical University Tokyo Japan.
FAU - Ishida, Yusuke
AU  - Ishida Y
AUID- ORCID: 0000-0002-2961-2938
AD  - Department of Anesthesiology Tokyo Medical University Tokyo Japan.
FAU - Tomino, Mikiko
AU  - Tomino M
AD  - Department of Anesthesiology Tokyo Medical University Tokyo Japan.
LA  - eng
PT  - Case Reports
DEP - 20230927
PL  - England
TA  - Clin Case Rep
JT  - Clinical case reports
JID - 101620385
PMC - PMC10533385
OTO - NOTNLM
OT  - disorder of consciousness (DOC)
OT  - electroencephalogram (EEG)
OT  - general anesthesia
OT  - nonconvulsive status epilepticus (NCSE)
COIS- The authors declare that they have no competing interests associated with this 
      manuscript.
EDAT- 2023/10/02 06:42
MHDA- 2023/10/02 06:43
PMCR- 2023/09/27
CRDT- 2023/10/02 04:35
PHST- 2023/08/08 00:00 [received]
PHST- 2023/09/11 00:00 [revised]
PHST- 2023/09/19 00:00 [accepted]
PHST- 2023/10/02 06:43 [medline]
PHST- 2023/10/02 06:42 [pubmed]
PHST- 2023/10/02 04:35 [entrez]
PHST- 2023/09/27 00:00 [pmc-release]
AID - CCR37988 [pii]
AID - 10.1002/ccr3.7988 [doi]
PST - epublish
SO  - Clin Case Rep. 2023 Sep 27;11(10):e7988. doi: 10.1002/ccr3.7988. eCollection 2023 
      Oct.