PMID- 37784197
OWN - NLM
STAT- MEDLINE
DCOM- 20231004
LR  - 20231121
IS  - 1745-6215 (Electronic)
IS  - 1745-6215 (Linking)
VI  - 24
IP  - 1
DP  - 2023 Oct 2
TI  - A self-managed exercise therapy program for wrist osteoarthritis: study protocol 
      for a randomized controlled trial.
PG  - 628
LID - 10.1186/s13063-023-07668-4 [doi]
LID - 628
AB  - BACKGROUND: Post-traumatic wrist osteoarthritis (OA) can eventually lead to pain, 
      muscular weakness, and stiffness of the wrist, which can affect the function of 
      the entire upper limb and reduce the quality of life. Although there is strong 
      evidence that all patients with OA should be offered adequate education and 
      exercises as a first-line treatment, an effective self-management program, 
      including structured education and therapeutic exercises, has not yet been 
      introduced for individuals with wrist OA. This trial aims to evaluate the 
      effectiveness of an exercise therapy program with joint protective strategies to 
      improve neuromuscular control (intervention group) compared to a training program 
      with range of motion exercises (control group). METHODS: This is a single-blinded 
      randomized controlled trial (RCT) with two treatment arms in patients with 
      symptomatic and radiographically confirmed wrist OA. The trial will be conducted 
      at a hand surgery department. The participants will be randomly assigned either 
      to a neuromuscular exercise therapy program or to a training program with range 
      of motion exercises only. Participants in both groups will receive a wrist 
      orthosis and structured education on wrist anatomy, pathophysiology, and joint 
      protective self-management strategies. The programs consist of home exercises 
      that will be performed twice a day for 12 weeks. The Patient-Rated Wrist 
      Evaluation (PRWE) is the primary outcome measure of pain and function. Wrist 
      range of motion (ROM), grip strength, the Numeric Pain Rating scale (NPRS), 
      Disabilities of the Arm, Shoulder, and Hand (DASH), the General Self-Efficacy 
      Scale (GSES), Global Rating of Change (GROC), and conversion to surgery are the 
      secondary measures of outcome. Assessments will be performed at baseline and at 
      3, 6, and 12 months after baseline by a blinded assessor. DISCUSSION: The 
      upcoming results from this trial may add new knowledge about the effectiveness of 
      a self-managed exercise therapy program on pain and function for individuals with 
      wrist OA. If the present self-management program proves to be effective, it can 
      redefine current treatment strategies and may be implemented in wrist OA 
      treatment protocols. TRIAL REGISTRATION: ClinicalTrials.gov, NCT05367817. 
      Retrospectively registered on 27 April 2022. https://clinicaltrials.gov .
CI  - (c) 2023. BioMed Central Ltd., part of Springer Nature.
FAU - Larsson, Sara L
AU  - Larsson SL
AUID- ORCID: 0000-0003-1188-7762
AD  - Department of Hand Surgery, Skane University Hospital, Malmo, Sweden. 
      sara.larsson.5408@med.lu.se.
AD  - Department of Translational Medicine - Hand Surgery, Lund University, Jan 
      Waldenstroms Gata 5, 205 03, Malmo, Sweden. sara.larsson.5408@med.lu.se.
FAU - Ekstrand, Elisabeth
AU  - Ekstrand E
AD  - Department of Hand Surgery, Skane University Hospital, Malmo, Sweden.
AD  - Department of Health Sciences, Lund University, Lund, Sweden.
FAU - Dahlin, Lars B
AU  - Dahlin LB
AD  - Department of Hand Surgery, Skane University Hospital, Malmo, Sweden.
AD  - Department of Translational Medicine - Hand Surgery, Lund University, Jan 
      Waldenstroms Gata 5, 205 03, Malmo, Sweden.
AD  - Department of Biomedical and Clinical Sciences, Linkoping University, Linkoping, 
      Sweden.
FAU - Bjorkman, Anders
AU  - Bjorkman A
AD  - Department of Hand Surgery, Institute of Clinical Sciences, Sahlgrenska 
      University Hospital, Sahlgrenska Academy, University of Gothenburg, Gothenburg, 
      Sweden.
FAU - Brogren, Elisabeth
AU  - Brogren E
AD  - Department of Hand Surgery, Skane University Hospital, Malmo, Sweden.
AD  - Department of Translational Medicine - Hand Surgery, Lund University, Jan 
      Waldenstroms Gata 5, 205 03, Malmo, Sweden.
LA  - eng
SI  - ClinicalTrials.gov/NCT05367817
PT  - Clinical Trial Protocol
PT  - Journal Article
DEP - 20231002
PL  - England
TA  - Trials
JT  - Trials
JID - 101263253
SB  - IM
MH  - Humans
MH  - *Osteoarthritis, Knee/therapy
MH  - Treatment Outcome
MH  - Wrist
MH  - *Self-Management
MH  - Exercise Therapy/adverse effects/methods
MH  - Pain
MH  - Quality of Life
MH  - Randomized Controlled Trials as Topic
PMC - PMC10546651
OTO - NOTNLM
OT  - Exercise therapy
OT  - Neuromuscular control
OT  - Randomized controlled trial
OT  - SLAC
OT  - SNAC
OT  - Self-management
OT  - Wrist osteoarthritis
COIS- The authors declare that they have no competing interests.
EDAT- 2023/10/03 00:42
MHDA- 2023/10/04 06:44
PMCR- 2023/10/02
CRDT- 2023/10/02 23:56
PHST- 2023/03/28 00:00 [received]
PHST- 2023/09/22 00:00 [accepted]
PHST- 2023/10/04 06:44 [medline]
PHST- 2023/10/03 00:42 [pubmed]
PHST- 2023/10/02 23:56 [entrez]
PHST- 2023/10/02 00:00 [pmc-release]
AID - 10.1186/s13063-023-07668-4 [pii]
AID - 7668 [pii]
AID - 10.1186/s13063-023-07668-4 [doi]
PST - epublish
SO  - Trials. 2023 Oct 2;24(1):628. doi: 10.1186/s13063-023-07668-4.