PMID- 37786466
OWN - NLM
STAT- MEDLINE
DCOM- 20231004
LR  - 20231012
IS  - 1735-3688 (Electronic)
IS  - 0253-0716 (Print)
IS  - 0253-0716 (Linking)
VI  - 48
IP  - 5
DP  - 2023 Sep
TI  - Association of Insomnia with Anxiety and Depression in Type 2 Diabetic Patients: 
      A Cross-Sectional Study.
PG  - 448-455
LID - 10.30476/ijms.2023.96017.2755 [doi]
AB  - BACKGROUND: Type 2 diabetes mellitus (T2DM) is associated with sleep disorders, 
      which in turn may lead to anxiety and depression. Sleep deprivation impairs 
      glucose metabolism causing a decrease in insulin sensitivity and glucose 
      tolerance. The present study aimed to determine the association of insomnia with 
      anxiety and depression in patients with T2DM. METHODS: A cross-sectional study 
      was conducted in 2020 at the Endocrinological Department of City Clinical 
      Hospital numero sign1, affiliated with Astana Medical University (Astana, Kazakhstan). A 
      total of 376 patients with decompensated T2DM were included in the study. 
      Insomnia was assessed using the Pittsburgh Sleep Quality Index (PSQI) and 
      Insomnia Severity Index (ISI). Anxiety and depression were assessed using the 
      Hospital Anxiety and Depression Scale (HADS). Multivariable logistic regression 
      was used to assess the association of insomnia with anxiety and depression. 
      RESULTS: All patients showed signs of sleep disturbances. Based on the HADS 
      cutoff score >8, anxiety and depression were observed in 48 (12.80%) and 46 
      (12.20%) patients, respectively. PSQI, ISI, and HADS indicators were associated 
      with an increased risk of anxiety and depression symptoms. In terms of anxiety, 
      the adjusted odds ratio for PSQI and ISI scores were 1.09 (P=0.08) and 1.07 
      (P=0.01), respectively. These for depression were 1.10 (P=0.06) and 1.07 
      (P=0.01), respectively. CONCLUSION: Sleep quality is an important indicator of 
      psychological health in patients with T2DM, especially those who exhibit signs of 
      anxiety and depression.
CI  - Copyright: (c) Iranian Journal of Medical Sciences.
FAU - Shinalieva, Karlyghash
AU  - Shinalieva K
AD  - Department of Neurology, National Joint Stock Company, Medical University Astana, 
      Astana, Kazakhstan.
FAU - Kasenova, Asemgul
AU  - Kasenova A
AD  - Department of Neurology, National Joint Stock Company, Medical University Astana, 
      Astana, Kazakhstan.
FAU - Akhmetzhanova, Zauresh
AU  - Akhmetzhanova Z
AD  - Department of Neurology, National Joint Stock Company, Medical University Astana, 
      Astana, Kazakhstan.
FAU - Alzhanova, Dinara
AU  - Alzhanova D
AD  - Department of Neurology, National Joint Stock Company, Medical University Astana, 
      Astana, Kazakhstan.
FAU - Eszhanova, Laura
AU  - Eszhanova L
AD  - Department of Neurology, National Joint Stock Company, Medical University Astana, 
      Astana, Kazakhstan.
FAU - Bekenova, Ainur
AU  - Bekenova A
AD  - Department of Neurology, National Joint Stock Company, Medical University Astana, 
      Astana, Kazakhstan.
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PL  - Iran
TA  - Iran J Med Sci
JT  - Iranian journal of medical sciences
JID - 8104374
SB  - IM
MH  - Humans
MH  - *Sleep Initiation and Maintenance Disorders/complications/epidemiology
MH  - Cross-Sectional Studies
MH  - Depression/complications/epidemiology
MH  - *Diabetes Mellitus, Type 2/complications/epidemiology
MH  - Anxiety/complications/epidemiology
PMC - PMC10541539
OTO - NOTNLM
OT  - Anxiety
OT  - Depression
OT  - Sleep disorders
OT  - Type 2 diabetes mellitus
COIS- None declared.
EDAT- 2023/10/03 06:47
MHDA- 2023/10/04 06:43
PMCR- 2023/09/01
CRDT- 2023/10/03 03:38
PHST- 2022/07/06 00:00 [received]
PHST- 2022/10/04 00:00 [revised]
PHST- 2022/11/11 00:00 [accepted]
PHST- 2023/10/04 06:43 [medline]
PHST- 2023/10/03 06:47 [pubmed]
PHST- 2023/10/03 03:38 [entrez]
PHST- 2023/09/01 00:00 [pmc-release]
AID - IJMS-48-5 [pii]
AID - 10.30476/ijms.2023.96017.2755 [doi]
PST - ppublish
SO  - Iran J Med Sci. 2023 Sep;48(5):448-455. doi: 10.30476/ijms.2023.96017.2755.