PMID- 37788930 OWN - NLM STAT- MEDLINE DCOM- 20231005 LR - 20231005 IS - 2044-6055 (Electronic) IS - 2044-6055 (Linking) VI - 13 IP - 10 DP - 2023 Oct 3 TI - Association between spinal and non-spinal health conditions reported in epidemiological studies: a scoping review protocol. PG - e075382 LID - 10.1136/bmjopen-2023-075382 [doi] AB - INTRODUCTION: The increasing prevalence of coexisting health conditions poses a challenge to healthcare providers and healthcare systems. Spinal pain (eg, neck and back pain) and spinal pathologies (eg, osteoporotic fractures and degenerative spinal disease) exist concurrently with other non-spinal health conditions (NSHC). However, the scope of what associations may exist among these co-occurring conditions is unclear. Therefore, this scoping review aims to map the epidemiological literature that reports associations between spine-related pain and pathologies (SPPs) and NSHCs. METHODS AND ANALYSIS: This scoping review will follow the JBI protocol and Preferred Reporting Items for Systematic reviews and Meta-Analyses extension for Scoping Reviews. We will systematically search the literature using key words and MeSH terms for SPPs and NSHCs. Terminology/vocabulary for NSHCs will include those for communicable and non-communicable diseases as reported by WHO Global Burden of Disease reports. Five databases will be searched from inception: MEDLINE, EMBASE, APA PsycInfo, Scopus and Web of Science Core Collection. Papers published in English, in peer-reviewed journals, including measures of association between SPPs and NSHCs and using observational epidemiologic study designs will be included. Excluded will be studies of cadaveric, animal or health behaviours; studies with no measures of association and non-observational epidemiologic studies. Results will include the number of studies, the studies that have evaluated the measures of association and the frequency of the studied associations between SPPs and NSHCs. Results will be reported in tables and diagrams. Themes of comorbidities will be synthesised into a descriptive report. ETHICS AND DISSEMINATION: This scoping review was deemed exempt from ethics review. This review will provide a comprehensive overview of the literature that reports associations between SPPs and NSHCs to inform future research initiatives and practices. Results will be disseminated through publication in peer-reviewed journals and research conferences. REGISTRATION DETAILS: https://osf.io/w49u3. CI - (c) Author(s) (or their employer(s)) 2023. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ. FAU - Green, Bart N AU - Green BN AUID- ORCID: 0000-0002-9906-6397 AD - Employer Based Integrated Primary Care Health Centers, Qualcomm Health Center, Stanford Health Care, San Diego, California, USA bngreen@aol.com. AD - National University of Health Sciences, Lombard, Illinois, USA. FAU - Johnson, Claire D AU - Johnson CD AD - National University of Health Sciences, Lombard, Illinois, USA. FAU - Crawford, Cindy AU - Crawford C AD - Warwick, New York, USA. FAU - Tavares, Patricia A AU - Tavares PA AD - Canadian Memorial Chiropractic College, Toronto, Ontario, Canada. FAU - Murnaghan, Kent AU - Murnaghan K AD - Canadian Memorial Chiropractic College, Toronto, Ontario, Canada. FAU - Haldeman, Scott AU - Haldeman S AD - Department of Neurology, University of California Irvine, Orange, California, USA. AD - World Spine Care, Tustin, California, USA. FAU - Hurwitz, Eric L AU - Hurwitz EL AD - Office of Public Health Studies, Thompson School of Social Work & Public Health, University of Hawaii at Manoa, Honolulu, Hawaii, USA. FAU - Yang, Haiou AU - Yang H AD - University of California, Irvine, California, USA. FAU - de Luca, Katie AU - de Luca K AD - CQUniversity Brisbane, Brisbane, Queensland, Australia. LA - eng PT - Journal Article PT - Research Support, Non-U.S. Gov't DEP - 20231003 PL - England TA - BMJ Open JT - BMJ open JID - 101552874 SB - IM MH - Animals MH - Humans MH - *Biological Phenomena MH - Databases, Factual MH - Epidemiologic Studies MH - Pain MH - Research Design MH - *Spinal Diseases/epidemiology MH - *Review Literature as Topic OTO - NOTNLM OT - back pain OT - bone diseases OT - epidemiologic studies OT - musculoskeletal disorders OT - public health OT - spine COIS- Competing interests: BNG serves on the speakers bureau for the NCMIC. CDJ is a board member for NCMIC and is the spouse of BNG. EDAT- 2023/10/04 00:42 MHDA- 2023/10/05 06:43 CRDT- 2023/10/03 21:39 PHST- 2023/10/05 06:43 [medline] PHST- 2023/10/04 00:42 [pubmed] PHST- 2023/10/03 21:39 [entrez] AID - bmjopen-2023-075382 [pii] AID - 10.1136/bmjopen-2023-075382 [doi] PST - epublish SO - BMJ Open. 2023 Oct 3;13(10):e075382. doi: 10.1136/bmjopen-2023-075382.