PMID- 37794371
OWN - NLM
STAT- MEDLINE
DCOM- 20231102
LR  - 20240315
IS  - 1471-2261 (Electronic)
IS  - 1471-2261 (Linking)
VI  - 23
IP  - 1
DP  - 2023 Oct 4
TI  - Assessment of fetal intraventricular diastolic fluid dynamics using ultrasound 
      vector flow mapping.
PG  - 488
LID - 10.1186/s12872-023-03524-0 [doi]
LID - 488
AB  - OBJECTIVE: The purpose of this study was to investigate the feasibility of 
      visualizing and quantifying the normal pattern of vortex formation in the left 
      ventricle (LV) and right ventricle (RV) of the fetal heart during diastole using 
      vector flow mapping (VFM). METHODS: A total of 36 healthy fetuses in the second 
      trimester (mean gestational age: 23 weeks, 2 days; range: 22-24 weeks) were 
      enrolled in the study. Color Doppler signals were recorded in the four-chamber 
      view to observe the phase of the diastolic vortices in the LV and RV. The vortex 
      area and circulation were measured, and parameters such as intraventricular 
      pressure difference (IVPD), intraventricular pressure gradient (IVPG), and 
      average energy loss (EL_AVG) were evaluated at different diastolic phases, 
      including isovolumic relaxation (D1), early diastole (D2), and late diastole 
      (D3). RESULTS: Healthy second-trimester fetal vortex formations were observed in 
      both the LV and RV at the end of diastole, with the vortices rotating in a 
      clockwise direction towards the outflow tract. There were no significant 
      differences in vortex area and circulation between the two ventricles (p > 0.05). 
      However, significant differences were found in IVPD, IVPG, and EL_AVG among the 
      diastolic phases (D1, D2, and D3) (p < 0.05). Trends in IVPD, IVPG, and EL_AVG 
      during diastole (D1-D2-D3) revealed increasing IVPD and EL_AVG values, as well as 
      decreasing IVPG values. Furthermore, during D3, the RV exhibited significantly 
      higher IVPD, IVPG, and EL_AVG compared to the LV (p > 0.05). CONCLUSION: VFM is a 
      valuable technique for analyzing the formation of vortices in the left and right 
      ventricles during fetal diastole. The application of VFM technology has the 
      potential to enhance the assessment of fetal cardiac parameters.
CI  - (c) 2023. BioMed Central Ltd., part of Springer Nature.
FAU - Shu, Qinglan
AU  - Shu Q
AD  - Ultrasound in Cardiac Electrophysiology and Biomechanics Key Laboratory of 
      Sichuan Province, Sichuan Provincial People's Hospital, Sichuan Provincial 
      People's Hospital, University of Electronic Science and Technology of China, 
      Chengdu, China.
AD  - Department of Cardiovascular Ultrasound & Noninvasive Cardiology, Sichuan 
      Provincial People's Hospital, University of Electronic Science and Technology of 
      China, Chengdu, China.
FAU - Wang, Yi
AU  - Wang Y
AD  - Ultrasound in Cardiac Electrophysiology and Biomechanics Key Laboratory of 
      Sichuan Province, Sichuan Provincial People's Hospital, Sichuan Provincial 
      People's Hospital, University of Electronic Science and Technology of China, 
      Chengdu, China.
AD  - Department of Cardiovascular Ultrasound & Noninvasive Cardiology, Sichuan 
      Provincial People's Hospital, University of Electronic Science and Technology of 
      China, Chengdu, China.
FAU - Lin, Xinyi
AU  - Lin X
AD  - School of Biomedical Sciences, Li Ka Shing Faculty of Medicine, The University of 
      Hong Kong, Hong Kong, China.
FAU - Xie, Shenghua
AU  - Xie S
AD  - Ultrasound in Cardiac Electrophysiology and Biomechanics Key Laboratory of 
      Sichuan Province, Sichuan Provincial People's Hospital, Sichuan Provincial 
      People's Hospital, University of Electronic Science and Technology of China, 
      Chengdu, China.
AD  - Department of Cardiovascular Ultrasound & Noninvasive Cardiology, Sichuan 
      Provincial People's Hospital, University of Electronic Science and Technology of 
      China, Chengdu, China.
FAU - Wang, Zhengyang
AU  - Wang Z
AD  - Ultrasound in Cardiac Electrophysiology and Biomechanics Key Laboratory of 
      Sichuan Province, Sichuan Provincial People's Hospital, Sichuan Provincial 
      People's Hospital, University of Electronic Science and Technology of China, 
      Chengdu, China.
AD  - Department of Cardiovascular Ultrasound & Noninvasive Cardiology, Sichuan 
      Provincial People's Hospital, University of Electronic Science and Technology of 
      China, Chengdu, China.
FAU - Wang, Sijia
AU  - Wang S
AD  - Ultrasound in Cardiac Electrophysiology and Biomechanics Key Laboratory of 
      Sichuan Province, Sichuan Provincial People's Hospital, Sichuan Provincial 
      People's Hospital, University of Electronic Science and Technology of China, 
      Chengdu, China.
AD  - Department of Cardiovascular Ultrasound & Noninvasive Cardiology, Sichuan 
      Provincial People's Hospital, University of Electronic Science and Technology of 
      China, Chengdu, China.
FAU - Yin, Lixue
AU  - Yin L
AD  - Ultrasound in Cardiac Electrophysiology and Biomechanics Key Laboratory of 
      Sichuan Province, Sichuan Provincial People's Hospital, Sichuan Provincial 
      People's Hospital, University of Electronic Science and Technology of China, 
      Chengdu, China. yinlixue_cardiac@163.com.
AD  - Department of Cardiovascular Ultrasound & Noninvasive Cardiology, Sichuan 
      Provincial People's Hospital, University of Electronic Science and Technology of 
      China, Chengdu, China. yinlixue_cardiac@163.com.
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PT  - Retracted Publication
DEP - 20231004
PL  - England
TA  - BMC Cardiovasc Disord
JT  - BMC cardiovascular disorders
JID - 100968539
SB  - IM
RIN - BMC Cardiovasc Disord. 2024 Mar 14;24(1):156. PMID: 38486168
MH  - Humans
MH  - Infant
MH  - Diastole
MH  - *Hydrodynamics
MH  - *Heart Ventricles/diagnostic imaging
MH  - Ultrasonography
MH  - Fetal Heart/diagnostic imaging
MH  - Ventricular Function, Left
PMC - PMC10552239
OTO - NOTNLM
OT  - Echocardiography
OT  - Energy loss
OT  - Hemodynamics
OT  - Intraventricular pressure gradients
OT  - Vector flow mapping
OT  - Vortex
COIS- None declared.
EDAT- 2023/10/05 01:00
MHDA- 2023/11/02 12:42
PMCR- 2023/10/04
CRDT- 2023/10/04 23:40
PHST- 2023/08/29 00:00 [received]
PHST- 2023/09/20 00:00 [accepted]
PHST- 2023/11/02 12:42 [medline]
PHST- 2023/10/05 01:00 [pubmed]
PHST- 2023/10/04 23:40 [entrez]
PHST- 2023/10/04 00:00 [pmc-release]
AID - 10.1186/s12872-023-03524-0 [pii]
AID - 3524 [pii]
AID - 10.1186/s12872-023-03524-0 [doi]
PST - epublish
SO  - BMC Cardiovasc Disord. 2023 Oct 4;23(1):488. doi: 10.1186/s12872-023-03524-0.