PMID- 37795364
OWN - NLM
STAT- MEDLINE
DCOM- 20231102
LR  - 20231106
IS  - 1664-2392 (Print)
IS  - 1664-2392 (Electronic)
IS  - 1664-2392 (Linking)
VI  - 14
DP  - 2023
TI  - Ultrasound-guided microwave ablation in the treatment of recurrent primary 
      hyperparathyroidism in a patient with MEN1: a case report.
PG  - 1175377
LID - 10.3389/fendo.2023.1175377 [doi]
LID - 1175377
AB  - BACKGROUND: Multiple endocrine neoplasia type 1 (MEN1) is an inherited endocrine 
      syndrome caused by the mutation in the tumor suppressor gene MEN1. The recurrence 
      rate of primary hyperparathyroidism (PHPT) in patients with MEN1 after 
      parathyroidectomy remains high, and the management of recurrent 
      hyperparathyroidism is still challenging. CASE PRESENTATION: We reported a 
      44-year-old woman with MEN1 combined with PHPT who was diagnosed through genetic 
      screening of the patient and her family members. After parathyroidectomy to 
      remove one parathyroid gland, the patient suffered from persistent high levels of 
      serum calcium and parathyroid hormone, which returned to normal at up to 8 months 
      after ultrasound-guided microwave ablation (MWA) for bilateral parathyroid 
      glands, suggesting an acceptable short-term prognosis. CONCLUSION: 
      Ultrasound-guided MWA for parathyroid nodules may be an effective therapeutic 
      strategy for recurrent PHPT in MEN1 patients.
CI  - Copyright (c) 2023 Liu, Zhao, Han, Hu, Zhang, Xu, Chen, Liu and Xu.
FAU - Liu, Zhoujun
AU  - Liu Z
AD  - Endocrine and Diabetes Center, The Affiliated Hospital of Integrated Traditional 
      Chinese and Western Medicine, Nanjing University of Chinese Medicine, Jiangsu 
      Province Academy of Traditional Chinese Medicine, Nanjing, China.
FAU - Zhao, Yueting
AU  - Zhao Y
AD  - Endocrine and Diabetes Center, The Affiliated Hospital of Integrated Traditional 
      Chinese and Western Medicine, Nanjing University of Chinese Medicine, Jiangsu 
      Province Academy of Traditional Chinese Medicine, Nanjing, China.
FAU - Han, Xue
AU  - Han X
AD  - Endocrine and Diabetes Center, The Affiliated Hospital of Integrated Traditional 
      Chinese and Western Medicine, Nanjing University of Chinese Medicine, Jiangsu 
      Province Academy of Traditional Chinese Medicine, Nanjing, China.
FAU - Hu, Xin
AU  - Hu X
AD  - Endocrine and Diabetes Center, The Affiliated Hospital of Integrated Traditional 
      Chinese and Western Medicine, Nanjing University of Chinese Medicine, Jiangsu 
      Province Academy of Traditional Chinese Medicine, Nanjing, China.
FAU - Zhang, Yuzhi
AU  - Zhang Y
AD  - Department of Ultrasound, The Affiliated Hospital of Integrated Traditional 
      Chinese and Western Medicine, Nanjing University of Chinese Medicine, Jiangsu 
      Province Academy of Traditional Chinese Medicine, Nanjing, China.
FAU - Xu, Lan
AU  - Xu L
AD  - Department of Endocrinology, The Affiliated Wuxi People's Hospital of Nanjing 
      Medical University, Wuxi, China.
FAU - Chen, Guofang
AU  - Chen G
AD  - Endocrine and Diabetes Center, The Affiliated Hospital of Integrated Traditional 
      Chinese and Western Medicine, Nanjing University of Chinese Medicine, Jiangsu 
      Province Academy of Traditional Chinese Medicine, Nanjing, China.
AD  - Key Laboratory of Tradtional Chinese Medicine Syndrome & Treatment of Yingbing 
      (Thyroid Disease) of State Administration of Traditional Chinese Medicine, 
      Jiangsu Province Academy of Traditional Chinese Medicine, Nanjing, China.
FAU - Liu, Chao
AU  - Liu C
AD  - Endocrine and Diabetes Center, The Affiliated Hospital of Integrated Traditional 
      Chinese and Western Medicine, Nanjing University of Chinese Medicine, Jiangsu 
      Province Academy of Traditional Chinese Medicine, Nanjing, China.
AD  - Key Laboratory of Tradtional Chinese Medicine Syndrome & Treatment of Yingbing 
      (Thyroid Disease) of State Administration of Traditional Chinese Medicine, 
      Jiangsu Province Academy of Traditional Chinese Medicine, Nanjing, China.
FAU - Xu, Shuhang
AU  - Xu S
AD  - Endocrine and Diabetes Center, The Affiliated Hospital of Integrated Traditional 
      Chinese and Western Medicine, Nanjing University of Chinese Medicine, Jiangsu 
      Province Academy of Traditional Chinese Medicine, Nanjing, China.
LA  - eng
PT  - Case Reports
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20230919
PL  - Switzerland
TA  - Front Endocrinol (Lausanne)
JT  - Frontiers in endocrinology
JID - 101555782
SB  - IM
MH  - Humans
MH  - Female
MH  - Adult
MH  - *Multiple Endocrine Neoplasia Type 1/complications/surgery/genetics
MH  - *Hyperparathyroidism, Primary/complications/diagnostic imaging/surgery
MH  - Microwaves/therapeutic use
MH  - Parathyroid Glands/diagnostic imaging/surgery/pathology
MH  - Ultrasonography, Interventional
PMC - PMC10546301
OTO - NOTNLM
OT  - case report
OT  - microwave ablation
OT  - multiple endocrine neoplasia
OT  - primary hyperparathyroidism
OT  - recurrence
COIS- The authors declare that the research was conducted in the absence of any 
      commercial or financial relationships that could be construed as a potential 
      conflict of interest.
EDAT- 2023/10/05 06:43
MHDA- 2023/11/02 12:46
PMCR- 2023/01/01
CRDT- 2023/10/05 04:10
PHST- 2023/02/27 00:00 [received]
PHST- 2023/09/04 00:00 [accepted]
PHST- 2023/11/02 12:46 [medline]
PHST- 2023/10/05 06:43 [pubmed]
PHST- 2023/10/05 04:10 [entrez]
PHST- 2023/01/01 00:00 [pmc-release]
AID - 10.3389/fendo.2023.1175377 [doi]
PST - epublish
SO  - Front Endocrinol (Lausanne). 2023 Sep 19;14:1175377. doi: 
      10.3389/fendo.2023.1175377. eCollection 2023.