PMID- 37799183
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20231026
IS  - 2231-0770 (Print)
IS  - 2249-4464 (Electronic)
IS  - 2231-0770 (Linking)
VI  - 13
IP  - 3
DP  - 2023 Jul
TI  - Yoga as Adjunct Therapy for Chronic Heart Failure: A Systematic Review and 
      Meta-Analysis of Randomized Controlled Trials.
PG  - 151-162
LID - 10.1055/s-0043-1774738 [doi]
AB  - Background  Chronic heart failure (CHF) is a prevalent cardiovascular condition 
      that can significantly impact the quality of life and increase mortality risk. 
      Yoga is a mind-body therapy that has been studied as a potential complementary 
      treatment for CHF. However, the effectiveness of yoga in improving outcomes in 
      patients with CHF remains uncertain. Methods  We conducted a systematic review of 
      randomized controlled trials (RCTs) evaluating the effects of yoga on outcomes in 
      patients with CHF. We searched the PubMed, Embase, Scopus, Cochrane Library, and 
      IndMED databases from inception to March 2023. The outcomes of interest were left 
      ventricular ejection fraction (LVEF), cardiac biomarkers, exercise capacity, 
      quality of life, and cardiac function. Results  We identified 11 RCTs that met 
      our inclusion criteria, involving a total of 552 participants. The meta-analysis 
      showed that yoga was associated with significant improvements in peak VO (2) 
      (mean difference [MD]= 3.29; 95% Confidence Interval [CI]: 1.64 to 4.94; I (2) = 
      0%), exercise capacity (MD=101.54; 95% CI: 6.24 to 196.83; I (2) = 96%), quality 
      of life (MD = -19.99; 95% CI: -25.76 to -14.22; I (2)  = 43%), NT-proBNP 
      (MD = -288.78; 95% CI: -492.20 to -85.37; I (2)  = 94%), and 6-minute walk test 
      (MD = 101.54; 95% CI: 6.24-196.83; I (2)  = 96%), but not in the left ventricular 
      ejection fraction (MD = 4.28; 95% CI: -1.14 to 9.70; I (2)  = 93%). Subgroup 
      analysis suggested that the effect of yoga on the quality of life is more 
      pronounced in patients with the "New York Heart Association" (NYHA) class I and 
      II CHF patients and in those who practiced yoga for longer durations. No serious 
      adverse events related to yoga were reported. Most of the included studies were 
      of "low" quality. Conclusion  Current evidence suggests that yoga may be an 
      effective complementary and integrative therapy for improving peak VO (2) 
      exercise capacity, NT-proBNP, and quality of life in patients with CHF. However, 
      the low-quality evidence does not render us to conclude anything beyond doubt or 
      draw any firm clinical recommendation. Future high-quality studies are needed to 
      explore the optimal duration and frequency of yoga practice and its effects on 
      long-term outcomes in this population.
CI  - The Author(s). This is an open access article published by Thieme under the terms 
      of the Creative Commons Attribution License, permitting unrestricted use, 
      distribution, and reproduction so long as the original work is properly cited. ( 
      https://creativecommons.org/licenses/by/4.0/ ).
FAU - Dutta, Abhijit
AU  - Dutta A
AUID- ORCID: 0000-0002-1864-0685
AD  - International Cooperation Section, Ministry of Ayush, Government of India, New 
      Delhi, India.
FAU - Mooventhan, Aruchunan
AU  - Mooventhan A
AD  - Department of Research, Government Yoga and Naturopathy Medical College, Chennai, 
      Tamil Nadu, India.
FAU - Nivethitha, L
AU  - Nivethitha L
AD  - Department of Naturopathy, Government Yoga and Naturopathy Medical College, 
      Chennai, Tamil Nadu, India.
LA  - eng
PT  - Journal Article
PT  - Review
DEP - 20230922
PL  - Germany
TA  - Avicenna J Med
JT  - Avicenna journal of medicine
JID - 101584155
PMC - PMC10550367
OTO - NOTNLM
OT  - peak VO 2
OT  - NT-proBNP
OT  - chronic heart failure
OT  - meditation
OT  - meta-analysis
OT  - quality of life
OT  - randomized controlled trials
OT  - systematic review
OT  - yoga
COIS- Conflict of Interest None declared.
EDAT- 2023/10/06 06:43
MHDA- 2023/10/06 06:44
PMCR- 2023/09/01
CRDT- 2023/10/06 03:45
PHST- 2023/10/06 06:44 [medline]
PHST- 2023/10/06 06:43 [pubmed]
PHST- 2023/10/06 03:45 [entrez]
PHST- 2023/09/01 00:00 [pmc-release]
AID - AJM-23-44 [pii]
AID - 10.1055/s-0043-1774738 [doi]
PST - epublish
SO  - Avicenna J Med. 2023 Sep 22;13(3):151-162. doi: 10.1055/s-0043-1774738. 
      eCollection 2023 Jul.