PMID- 37806237
OWN - NLM
STAT- MEDLINE
DCOM- 20231107
LR  - 20231215
IS  - 1873-460X (Electronic)
IS  - 1056-8727 (Linking)
VI  - 37
IP  - 11
DP  - 2023 Nov
TI  - The correlation between visceral fat/subcutaneous fat area ratio and 
      monocyte/high-density lipoprotein ratio in patients with type 2 diabetes mellitus 
      and albuminuria.
PG  - 108521
LID - S1056-8727(23)00119-8 [pii]
LID - 10.1016/j.jdiacomp.2023.108521 [doi]
AB  - OBJECTIVE: This study aims to observe the correlation between the visceral 
      fat/subcutaneous fat area ratio (VSR) and peripheral blood monocyte/high-density 
      lipoprotein ratio (MHR) in patients with type 2 diabetes mellitus (T2DM) and 
      albuminuria. METHODS: Based on the urinary albumin/creatinine ratio (UACR), 89 
      T2DM patients were divided into normo-albuminuria group (n = 49, UACR <30 mg/g) 
      and albuminuria group (n = 40, UACR >/=30 mg/g). Gender, age, body mass index 
      (BMI), duration of T2DM, blood pressure, visceral fat area (VA), subcutaneous fat 
      area (SA), biochemical indexes of blood serum and urinary were collected and 
      compared between the two groups, and the relationship between VSR and MHR was 
      analyzed in albuminuria group. RESULTS: No significant differences existed in 
      gender, age, BMI, duration of diabetes, blood pressure, serum lipids, and 
      hemoglobin Alc between the two groups. The levels of VA, VSR, MHR, and UACR were 
      higher in the albuminuria group (P < 0.05). VSR was positively correlated with 
      MHR (r = 0.39, P < 0.01), whereas VA was not significantly correlated with MHR in 
      the albuminuria group. CONCLUSION: Compared with VA, VSR was significantly 
      correlated with MHR, suggesting that VSR is more closely related to the 
      occurrence of chronic inflammation in type 2 diabetics with albuminuria.
CI  - Copyright (c) 2023. Published by Elsevier Inc.
FAU - Lin, Haiyan
AU  - Lin H
AD  - Department of Endocrinology, Maanshan General Hospital of Ranger-Duree 
      Healthcare, Maanshan, Anhui, China.
FAU - Zhu, Jun
AU  - Zhu J
AD  - Department of Endocrinology, Maanshan General Hospital of Ranger-Duree 
      Healthcare, Maanshan, Anhui, China.
FAU - Zheng, Chen
AU  - Zheng C
AD  - Department of Endocrinology, Maanshan General Hospital of Ranger-Duree 
      Healthcare, Maanshan, Anhui, China.
FAU - Xu, Xiaoming
AU  - Xu X
AD  - Department of Endocrinology, Maanshan General Hospital of Ranger-Duree 
      Healthcare, Maanshan, Anhui, China.
FAU - Ye, Shandong
AU  - Ye S
AD  - Department of Endocrinology, The First Affiliated Hospital of USTC (Anhui 
      Provincial Hospital), Division of Life Sciences and Medicine, Hefei, Anhui 
      230001, China. Electronic address: ysdhfl964@163.com.
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20230530
PL  - United States
TA  - J Diabetes Complications
JT  - Journal of diabetes and its complications
JID - 9204583
RN  - 0 (Lipoproteins, HDL)
RN  - AYI8EX34EU (Creatinine)
SB  - IM
MH  - Humans
MH  - *Diabetes Mellitus, Type 2/complications
MH  - Monocytes
MH  - Lipoproteins, HDL
MH  - Albuminuria/complications
MH  - Intra-Abdominal Fat
MH  - Subcutaneous Fat
MH  - Creatinine
OTO - NOTNLM
OT  - Albuminuria
OT  - Monocyte/high-density lipoprotein ratio
OT  - Type 2 diabetes mellitus
OT  - Visceral fat/subcutaneous fat area ratio
COIS- Declaration of competing interest All authors declare no competing interests.
EDAT- 2023/10/09 00:42
MHDA- 2023/11/07 06:46
CRDT- 2023/10/08 18:17
PHST- 2023/04/01 00:00 [received]
PHST- 2023/05/24 00:00 [revised]
PHST- 2023/05/28 00:00 [accepted]
PHST- 2023/11/07 06:46 [medline]
PHST- 2023/10/09 00:42 [pubmed]
PHST- 2023/10/08 18:17 [entrez]
AID - S1056-8727(23)00119-8 [pii]
AID - 10.1016/j.jdiacomp.2023.108521 [doi]
PST - ppublish
SO  - J Diabetes Complications. 2023 Nov;37(11):108521. doi: 
      10.1016/j.jdiacomp.2023.108521. Epub 2023 May 30.