PMID- 37809394
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20231031
IS  - 2405-8440 (Print)
IS  - 2405-8440 (Electronic)
IS  - 2405-8440 (Linking)
VI  - 9
IP  - 9
DP  - 2023 Sep
TI  - The role of chromium supplementation in cardiovascular risk factors: A 
      comprehensive reviews of putative molecular mechanisms.
PG  - e19826
LID - 10.1016/j.heliyon.2023.e19826 [doi]
LID - e19826
AB  - In the recent years, micronutrients play an important role in improving body 
      health with preventing and treating of chronic diseases. Chromium is one of the 
      vital minerals involved in the regulation of insulin action. According to 
      abundant evidences this mineral seems to be an essential factor involved in the 
      reduction of insulin resistance and decreasing the risk of type 2 diabetes 
      mellitus (T2DM) and cardiovascular diseases (CVDs). Moreover, it has been 
      proposed that Chromium supplementation affects mechanisms involved in blood 
      pressure, lipid metabolism, inflammation, and oxidative stress. For instance, it 
      may affect blood pressure through alteration of the renin-angiotensin system, as 
      well as reducing the angiotensin-converting enzyme activity. Furthermore, 
      Chromium supplementation might help reduce the coronary heart disease rates. This 
      study aims to provide a comprehensive review regarding to the effects of Chromium 
      supplementation on CVDs risk factors with an emphasis on possible molecular 
      mechanisms.
CI  - (c) 2023 The Authors.
FAU - Gossa Al-Saadde, Dhiaa Lattef
AU  - Gossa Al-Saadde DL
AD  - Department of Internal Medicine, College of Medicine, Basrah University Teaching 
      Hospital, Basrah, Iraq.
FAU - Haider, Ali Murtaza
AU  - Haider AM
AD  - Faisalabad Medical University, Faisalabad, Pakistan.
FAU - Ali, Arsalan
AU  - Ali A
AD  - Rawalpindi Medical University, Rawalpindi, Pakistan.
FAU - Abdu Musad Saleh, Ebraheem
AU  - Abdu Musad Saleh E
AD  - Department of Chemistry, Prince Sattam Bin Abdulaziz University, College of Arts 
      and Science, Wadi Al-Dawasir, 11991, Saudi Arabia.
FAU - Turki Jalil, Abduladheem
AU  - Turki Jalil A
AD  - Medical Laboratories Techniques Department, Al-Mustaqbal University College, 
      Babylon, Hilla, 51001, Iraq.
FAU - Abdulelah, Furqan M
AU  - Abdulelah FM
AD  - College of Pharmacy, Al-Bayan University, Baghdad, Iraq.
FAU - Romero-Parra, Rosario Mireya
AU  - Romero-Parra RM
AD  - Department of General Studies, Universidad Continental, Lima, Peru.
FAU - Tayyib, Nahla A
AU  - Tayyib NA
AD  - Faculty of Nursing, Umm Al-Qura University, Makkah, Saudi Arabia.
FAU - Ramirez-Coronel, Andres Alexis
AU  - Ramirez-Coronel AA
AD  - Catholic University of Cuenca, Azogues Campus, Ecuador.
AD  - University of Palermo, Buenos Aires, Argentina.
AD  - National University of Education, Azogues, Ecuador.
AD  - CES University, Colombia.
FAU - Alkhayyat, Ameer S
AU  - Alkhayyat AS
AD  - Medical Laboratory Technology Department, College of Medical Technology, The 
      Islamic University, Najaf, Iraq.
LA  - eng
PT  - Journal Article
PT  - Review
DEP - 20230904
PL  - England
TA  - Heliyon
JT  - Heliyon
JID - 101672560
PMC - PMC10559203
OTO - NOTNLM
OT  - Cardiovascular diseases
OT  - Chromium
OT  - Hypertension
OT  - Inflammation
OT  - Oxidative stress
COIS- The authors declare that they have no known competing financial interests or 
      personal relationships that could have appeared to influence the work reported in 
      this paper.
EDAT- 2023/10/09 06:42
MHDA- 2023/10/09 06:43
PMCR- 2023/09/04
CRDT- 2023/10/09 05:54
PHST- 2022/11/09 00:00 [received]
PHST- 2023/08/25 00:00 [revised]
PHST- 2023/09/01 00:00 [accepted]
PHST- 2023/10/09 06:43 [medline]
PHST- 2023/10/09 06:42 [pubmed]
PHST- 2023/10/09 05:54 [entrez]
PHST- 2023/09/04 00:00 [pmc-release]
AID - S2405-8440(23)07034-2 [pii]
AID - e19826 [pii]
AID - 10.1016/j.heliyon.2023.e19826 [doi]
PST - epublish
SO  - Heliyon. 2023 Sep 4;9(9):e19826. doi: 10.1016/j.heliyon.2023.e19826. eCollection 
      2023 Sep.