PMID- 37812148 OWN - NLM STAT- MEDLINE DCOM- 20240103 LR - 20240103 IS - 1568-5624 (Electronic) IS - 0920-5063 (Linking) VI - 35 IP - 1 DP - 2024 Jan TI - Mechanical and antibacterial properties of hybrid polymers composite reinforcement for biomedical applications. PG - 85-108 LID - 10.1080/09205063.2023.2268949 [doi] AB - This research investigates the biocompatibility, mechanical strength, and tribological properties of a hybrid composite material composed of high-density polyethylene (HDPE), hydroxyapatite (HAp), and titanium dioxide nanoparticles (Ti O2). The study explores the microstructural characteristics of the composite material using scanning electron microscopy (SEM), transmission electron microscopy (TEM), and X-ray diffraction (XRD). Samples of HDPE-30%HAp with varying concentrations of Ti O2 (5, 10, 15, and 20%) were prepared and extruded using a twin-screw machine. The hybrid composite materials underwent mechanical tests (tensile, flexural, and hardness), tribological tests (friction and wear rate), and antibacterial tests (resistance to Escherichia coli and Staphylococcus aureus bacteria). The results indicate that the optimal hybrid composite sample was HDPE-30%HAP-10% Ti O2, which demonstrated excellent mechanical properties (maximum tensile strength of 25.93 MPa and young modulus of 480 MPa) and a low coefficient of friction (COF approximately 0.07) while achieving high wear resistance (wear rate in the order of 10-4 m m3N-1 m-1). The study shows that the improvement in mechanical properties results in a corresponding improvement in tribological properties. The antibacterial tests revealed that the hybrid composite material exhibited resistance to E. coli and S. aureus bacteria. The findings of this study suggest that the HDPE-30%HAP-10% Ti O2 composite is a promising material for use in biomedical applications due to its excellent biocompatibility and desirable mechanical and tribological properties. The study demonstrates the potential of reinforced hybrid composite materials in overcoming the disadvantages of monolithic and hybrid micro-composites and highlights the importance of investigating the microstructural, tribological, and mechanical strength characteristics of composite materials for biomedical applications. FAU - Babers, N AU - Babers N AD - Mechatronic Program Faculty of Engineering and Technology, Egyptian Chinese University, Cairo, Egypt. FAU - El-Sherbiny, M G D AU - El-Sherbiny MGD AD - Mechanical Design and Production Engineering Department, Cairo University, Giza, Egypt. FAU - El-Shazly, M AU - El-Shazly M AD - Mechanical Design and Production Engineering Department, Cairo University, Giza, Egypt. FAU - Kamel, Bahaa M AU - Kamel BM AD - Mechanical Engineering Department, National Research Centre, Giza, Egypt. AD - Korean Egyptian Faculty for Industry and Energy Technology, Beni-Suef Technological University, Egypt. LA - eng PT - Journal Article DEP - 20240102 PL - England TA - J Biomater Sci Polym Ed JT - Journal of biomaterials science. Polymer edition JID - 9007393 RN - 9002-88-4 (Polyethylene) RN - 0 (Polymers) RN - 91D9GV0Z28 (Durapatite) RN - 0 (Dental Materials) RN - 0 (Anti-Bacterial Agents) SB - IM MH - *Polyethylene/chemistry MH - Materials Testing MH - *Polymers/pharmacology MH - Escherichia coli MH - Staphylococcus aureus MH - Durapatite/chemistry MH - Dental Materials MH - Anti-Bacterial Agents/pharmacology OTO - NOTNLM OT - Tribology OT - additives OT - high-density polyethylene OT - hybrid composite OT - nanoparticles OT - titanium dioxide EDAT- 2023/10/09 12:42 MHDA- 2024/01/03 09:42 CRDT- 2023/10/09 10:32 PHST- 2024/01/03 09:42 [medline] PHST- 2023/10/09 12:42 [pubmed] PHST- 2023/10/09 10:32 [entrez] AID - 10.1080/09205063.2023.2268949 [doi] PST - ppublish SO - J Biomater Sci Polym Ed. 2024 Jan;35(1):85-108. doi: 10.1080/09205063.2023.2268949. Epub 2024 Jan 2.