PMID- 37815695
OWN - NLM
STAT- MEDLINE
DCOM- 20240126
LR  - 20240204
IS  - 1867-108X (Electronic)
IS  - 1867-1071 (Linking)
VI  - 42
IP  - 2
DP  - 2024 Feb
TI  - Efficacy of uterine artery embolization (UAE) for uterine fibroids according to 
      FIGO classification: a single-center experience.
PG  - 174-181
LID - 10.1007/s11604-023-01492-1 [doi]
AB  - OBJECTIVE: This study aims to retrospectively evaluate the outcomes of uterine 
      artery embolization (UAE) for uterine fibroids (UFs), specifically submucosal 
      UFs, according to the International Federation of Gynecology and Obstetrics 
      (FIGO) classification of UFs. MATERIALS AND METHODS: Forty-two patients with 
      symptomatic UFs underwent UAE with Embosphere((R)) between July 2016 and November 
      2021. MRI was performed before, at 3 and 6 months after the UAE. At each 
      examination, the volume of UF was measured, and the percentage volume reduction 
      rate (VRR) was calculated. The technical success rate (TSR), symptom improvement 
      rate (SIR), regrowth rate (RR) after 6 months, and adverse events (AEs) were 
      examined; VRR was compared between patients with submucosal UFs (FIGO types 0-2, 
      group A), those with submucosal contacts (FIGO type 3, group B), and those 
      without submucosal UFs (FIGO types 4-7, group C). Statistical analysis was 
      performed on the difference in VRR between groups A, B, and C at 3 and 6 months 
      after UAE. The relationship with hormone levels before UAE and VRR was evaluated. 
      RESULTS: Thirty-seven of the 42 patients were evaluated. Overall, VRR was 37.0% 
      at 3 months and 52.1% at 6 months; TSR, SIR, and RR were 100%, 95.2%, and 5.4%, 
      respectively; VRR at 6 months was 80.7% for group A (n = 7), 57.8% for group B 
      (n = 13), and 37.1% for group C (n = 17). Significant differences were found 
      between A and C (p < 0.001) and B and C (p = 0.023). Hormone levels before UAE 
      had no effect on VRR. There was no significant AEs other than grade 3 pulmonary 
      embolism in one patient. CONCLUSION: UAE was effective for submucosal FIGO types 
      0-3. UAE was especially useful as an option for FIGO type 3 with a low protrusion 
      rate that is difficult to treat with transcervical resection.
CI  - (c) 2023. The Author(s) under exclusive licence to Japan Radiological Society.
FAU - Ito, Hiroe
AU  - Ito H
AD  - Department of Obstetrics and Gynecology, Tokyo Medical University, 6-7-1, 
      Nishishinjuku, Shinjuku-Ku, Tokyo, Japan.
FAU - Nakai, Motoki
AU  - Nakai M
AUID- ORCID: 0000-0001-7300-6030
AD  - Department of Radiology, Tokyo Medical University, 6-7-1, Nishishinjuku, 
      Shinjuku-Ku, Tokyo, Japan. toidai.nakai@gmail.com.
FAU - Yunaiyama, Daisuke
AU  - Yunaiyama D
AD  - Department of Radiology, Tokyo Medical University, 6-7-1, Nishishinjuku, 
      Shinjuku-Ku, Tokyo, Japan.
FAU - Shirota, Natsuhiko
AU  - Shirota N
AD  - Department of Radiology, Tokyo Medical University, 6-7-1, Nishishinjuku, 
      Shinjuku-Ku, Tokyo, Japan.
FAU - Kobayashi, Takehiro
AU  - Kobayashi T
AD  - Department of Radiology, Tokyo Medical University, 6-7-1, Nishishinjuku, 
      Shinjuku-Ku, Tokyo, Japan.
FAU - Yasutomi, Mika
AU  - Yasutomi M
AD  - Department of Radiology, Tokyo Medical University, 6-7-1, Nishishinjuku, 
      Shinjuku-Ku, Tokyo, Japan.
FAU - Kikuchi, Takayuki
AU  - Kikuchi T
AD  - Department of Obstetrics and Gynecology, Tokyo Medical University, 6-7-1, 
      Nishishinjuku, Shinjuku-Ku, Tokyo, Japan.
FAU - Kinoshita, Yuta
AU  - Kinoshita Y
AD  - Department of Obstetrics and Gynecology, Tokyo Medical University, 6-7-1, 
      Nishishinjuku, Shinjuku-Ku, Tokyo, Japan.
FAU - Takara, Yuki
AU  - Takara Y
AD  - Department of Radiology, Tokyo Medical University, 6-7-1, Nishishinjuku, 
      Shinjuku-Ku, Tokyo, Japan.
FAU - Tanaka, Taro
AU  - Tanaka T
AD  - Department of Radiology, Tokyo Medical University, 6-7-1, Nishishinjuku, 
      Shinjuku-Ku, Tokyo, Japan.
FAU - Saguchi, Toru
AU  - Saguchi T
AD  - Department of Radiology, Tokyo Medical University, 6-7-1, Nishishinjuku, 
      Shinjuku-Ku, Tokyo, Japan.
FAU - Saito, Kazuhiro
AU  - Saito K
AD  - Department of Radiology, Tokyo Medical University, 6-7-1, Nishishinjuku, 
      Shinjuku-Ku, Tokyo, Japan.
LA  - eng
PT  - Journal Article
DEP - 20231010
PL  - Japan
TA  - Jpn J Radiol
JT  - Japanese journal of radiology
JID - 101490689
RN  - 0 (Hormones)
SB  - IM
MH  - Pregnancy
MH  - Female
MH  - Humans
MH  - *Uterine Artery Embolization
MH  - *Uterine Neoplasms/therapy
MH  - Retrospective Studies
MH  - Treatment Outcome
MH  - *Leiomyoma/diagnostic imaging/therapy
MH  - Hormones
OTO - NOTNLM
OT  - FIGO classification
OT  - Magnetic resonance imaging
OT  - Submucosal uterine fibroid
OT  - Uterine artery embolization
EDAT- 2023/10/10 12:42
MHDA- 2024/01/26 06:43
CRDT- 2023/10/10 11:11
PHST- 2023/01/16 00:00 [received]
PHST- 2023/09/13 00:00 [accepted]
PHST- 2024/01/26 06:43 [medline]
PHST- 2023/10/10 12:42 [pubmed]
PHST- 2023/10/10 11:11 [entrez]
AID - 10.1007/s11604-023-01492-1 [pii]
AID - 10.1007/s11604-023-01492-1 [doi]
PST - ppublish
SO  - Jpn J Radiol. 2024 Feb;42(2):174-181. doi: 10.1007/s11604-023-01492-1. Epub 2023 
      Oct 10.