PMID- 37821036
OWN - NLM
STAT- MEDLINE
DCOM- 20231030
LR  - 20231110
IS  - 1096-0309 (Electronic)
IS  - 0003-2697 (Linking)
VI  - 682
DP  - 2023 Dec 1
TI  - A novel molecularly imprinted electrochemical sensor for the ultrasensitive 
      detection of tert-butylhydroquinone in edible oils.
PG  - 115348
LID - S0003-2697(23)00313-5 [pii]
LID - 10.1016/j.ab.2023.115348 [doi]
AB  - Tert-butylhydroquinone (TBHQ) is widely used to increase the stability of food 
      products; however, it is considered to be a highly unsafe preservative ingredient 
      that has caused serious damage to human health. Thus, in this paper, a novel 
      molecularly imprinted electrochemical sensor was designed for ultrasensitive, and 
      selective detection of TBHQ in edible oils. The sensor was based on the 
      molecularly imprinted polymer (MIP) synthesized with multiwalled carbon nanotube 
      (MWCNT), and gold nanoparticle (GNP), as the coating materials, 
      o-phenylenediamine (o-PDA) as the functional monomer, and TBHQ as the template 
      molecule. The electrochemical behavior of MIP/GNP/MWCNT/GCE was studied using 
      several electrochemical methods, which showed a low detection limit of 5 nM. 
      Furthermore the sensor demostrated excellent stability, selectivity, 
      repeatability, and reproducibility. It was successfully used to detect TBHQ in 
      edible oils, with recoveries ranging from 98.44% to 102.09% and relative standard 
      deviations (RSDs) of less than 2.16%, indicating that TBHQ detection in actual 
      samples is both possible and accurate.
CI  - Copyright (c) 2023. Published by Elsevier Inc.
FAU - Mohammed Albayati, Safaa Hashim
AU  - Mohammed Albayati SH
AD  - Northern Technical University, College of Health and Medical Techniques, 
      Department of Renal Dialysis Techniques, Kirkuk, Iraq.
FAU - Ustundag, Zafer
AU  - Ustundag Z
AD  - Dumlupinar University, Faculty of Science, Department of Chemistry, Kutahya, 
      Turkiye.
FAU - Soylu, Pervin
AU  - Soylu P
AD  - Selcuk University, Faculty of Science, Department of Chemistry, 42031, Konya, 
      Turkiye. Electronic address: pervindeveci@gmail.com.
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20231013
PL  - United States
TA  - Anal Biochem
JT  - Analytical biochemistry
JID - 0370535
RN  - C12674942B (2-tert-butylhydroquinone)
RN  - 0 (Polymers)
RN  - 7440-57-5 (Gold)
RN  - 0 (Oils)
SB  - IM
MH  - Humans
MH  - Polymers/chemistry
MH  - Gold/chemistry
MH  - Reproducibility of Results
MH  - *Metal Nanoparticles/chemistry
MH  - Oils
MH  - Electrochemical Techniques/methods
MH  - Limit of Detection
MH  - *Molecular Imprinting/methods
MH  - Electrodes
OTO - NOTNLM
OT  - Edible oils
OT  - Food preservatives
OT  - Gold nanoparticles
OT  - Molecular imprinting techniques
OT  - Phenolic antioxidants
COIS- Declaration of competing interest The authors declare that they have no known 
      competing financial interests or personal relationships that could have appeared 
      to influence the work reported in this paper.
EDAT- 2023/10/12 00:43
MHDA- 2023/10/30 06:46
CRDT- 2023/10/11 19:41
PHST- 2023/08/22 00:00 [received]
PHST- 2023/09/22 00:00 [revised]
PHST- 2023/10/08 00:00 [accepted]
PHST- 2023/10/30 06:46 [medline]
PHST- 2023/10/12 00:43 [pubmed]
PHST- 2023/10/11 19:41 [entrez]
AID - S0003-2697(23)00313-5 [pii]
AID - 10.1016/j.ab.2023.115348 [doi]
PST - ppublish
SO  - Anal Biochem. 2023 Dec 1;682:115348. doi: 10.1016/j.ab.2023.115348. Epub 2023 Oct 
      13.