PMID- 37829744
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20231031
IS  - 2536-4553 (Electronic)
IS  - 2148-4902 (Print)
IS  - 2536-4553 (Linking)
VI  - 10
IP  - 5
DP  - 2023
TI  - Evaluation of the predictive value of total IgE and absolute eosinophil levels on 
      allergy test positivity.
PG  - 602-608
LID - 10.14744/nci.2023.44827 [doi]
AB  - OBJECTIVE: Atopic diseases are the most common chronic conditions in childhood. 
      The best treatment for allergic disease is possible with early diagnosis. The 
      purpose of the study was to assess the predictive value of total immunoglobulin E 
      (IgE) and eosinophil levels for allergy test positivity in patients diagnosed 
      with asthma, allergic rhinitis (AR), atopic dermatitis (AD), and food allergy 
      (FA). METHODS: Pediatric patients between 0 and 18 years old diagnosed with 
      asthma, AR, AD, and FA were included in the study. Demographic characteristics of 
      the patients, total IgE, eosinophil (absolute and %) values, specific igE 
      (SPIGE), and skin prick test (SPT) results were recorded. RESULTS: The data of 
      2665 patients were evaluated in the study. Of the patients, 58.6% were male, 
      whereas 41.4% were female. The median age of the children was significantly 
      higher both in SPT-positive and SPIGE-positive patients (p<0.001). If the 
      criteria positivity is accepted as total IgE value is >/=104.5 (for AD: 86.5, 
      asthma: 116.5, AR: 120.5, FA: 42.5) and absolute eosinophil >/=500 and/or 
      eosinophil (%) >/=5%; test positivity was higher for each disease and all patients 
      (p<0.001). CONCLUSION: Total IgE and eosinophil levels can be used to identify 
      atopy in patients with symptoms of AD, asthma, and AR. Total IgE and eosinophil 
      values are suitable and easily obtainable parameters for better evaluation of 
      health-care resources for the diagnosis and follow-up of atopic illnesses.
CI  - (c) Copyright 2023 by Istanbul Provincial Directorate of Health.
FAU - Saglam, Neslihan Ozkul
AU  - Saglam NO
AD  - Department of Pediatrics, Umraniye Training and Research Hospital, Istanbul, 
      Turkiye.
FAU - Ozkars, Mehmet Yasar
AU  - Ozkars MY
AD  - Department of Pediatric Allergy and Immunology, Umraniye Training and Research 
      Hospital, Istanbul, Turkiye.
FAU - Altas, Ugur
AU  - Altas U
AD  - Department of Pediatric Allergy and Immunology, Umraniye Training and Research 
      Hospital, Istanbul, Turkiye.
FAU - Altas, Zeynep Meva
AU  - Altas ZM
AD  - Umraniye Provincial Health Directorate, Istanbul, Turkiye.
LA  - eng
PT  - Journal Article
DEP - 20230914
PL  - Turkey
TA  - North Clin Istanb
JT  - Northern clinics of Istanbul
JID - 101684520
PMC - PMC10565740
OTO - NOTNLM
OT  - Allergy test positivity
OT  - eosinophil levels
OT  - total IgE
COIS- No conflict of interest was declared by the authors.
EDAT- 2023/10/13 06:46
MHDA- 2023/10/13 06:47
PMCR- 2023/09/14
CRDT- 2023/10/13 04:11
PHST- 2023/03/24 00:00 [received]
PHST- 2023/05/10 00:00 [revised]
PHST- 2023/07/12 00:00 [accepted]
PHST- 2023/10/13 06:47 [medline]
PHST- 2023/10/13 06:46 [pubmed]
PHST- 2023/10/13 04:11 [entrez]
PHST- 2023/09/14 00:00 [pmc-release]
AID - NCI-10-602 [pii]
AID - 10.14744/nci.2023.44827 [doi]
PST - epublish
SO  - North Clin Istanb. 2023 Sep 14;10(5):602-608. doi: 10.14744/nci.2023.44827. 
      eCollection 2023.