PMID- 37836726
OWN - NLM
STAT- MEDLINE
DCOM- 20231023
LR  - 20231023
IS  - 1420-3049 (Electronic)
IS  - 1420-3049 (Linking)
VI  - 28
IP  - 19
DP  - 2023 Sep 30
TI  - Simultaneous Determination of Pesticide Residues and Mycotoxins in Storage Pu-erh 
      Tea Using Ultra-High-Performance Liquid Chromatography Coupled with Tandem Mass 
      Spectrometry.
LID - 10.3390/molecules28196883 [doi]
LID - 6883
AB  - Mycotoxins and pesticides are the most concerning chemical contaminants that can 
      affect the quality of Pu-erh tea during its production and storage. This study 
      presents a method that can simultaneously determine 31 pesticide residues and six 
      mycotoxins in Pu-erh tea within 11 min using ultra-high-performance liquid 
      chromatography coupled with tandem mass spectrometry (UPLC-MS/MS) after QuEChERS 
      extraction. The lower limit of quantification (LOQ) for all analytes ranged 
      between 0.06 and 50 ppb. Recoveries for each pesticide and mycotoxin ranged 
      between 62.0 and 130.3%, with intra- and inter-day precisions lower than 15%. 
      Good linear relationships were obtained, with correlation coefficients of r(2) > 
      0.991 for all analytes. The established method was applied to 31 Pu-erh tea 
      samples, including raw and ripened Pu-erh tea with different storage times. As a 
      result, pesticide residues were not detected in any of the collected samples, and 
      the mycotoxins detected in the samples were well below the official maximum 
      residue limits (MRLs). Notably, the levels of aflatoxin B(1) (AFB1), aflatoxin 
      G(1) (AFG1) and aflatoxin G(2) (AFG2) were lower than 1 ppb in the samples stored 
      for more than 30 years.
FAU - Chau, Siu Leung
AU  - Chau SL
AD  - School of Chinese Medicine, Hong Kong Baptist University, Kowloon Tong, Hong 
      Kong, China.
FAU - Zhao, Aihua
AU  - Zhao A
AD  - Shanghai Sixth People's Hospital Affiliated to Shanghai Jiao Tong University 
      School of Medicine, Shanghai 200023, China.
FAU - Jia, Wei
AU  - Jia W
AUID- ORCID: 0000-0002-3739-8994
AD  - School of Chinese Medicine, Hong Kong Baptist University, Kowloon Tong, Hong 
      Kong, China.
FAU - Wang, Lu
AU  - Wang L
AUID- ORCID: 0000-0002-3918-3399
AD  - School of Chinese Medicine, Hong Kong Baptist University, Kowloon Tong, Hong 
      Kong, China.
LA  - eng
PT  - Journal Article
DEP - 20230930
PL  - Switzerland
TA  - Molecules
JT  - Molecules (Basel, Switzerland)
JID - 100964009
RN  - 0 (Mycotoxins)
RN  - 0 (Pesticide Residues)
RN  - 0 (Tea)
SB  - IM
MH  - Chromatography, High Pressure Liquid/methods
MH  - *Mycotoxins/chemistry
MH  - Tandem Mass Spectrometry/methods
MH  - Chromatography, Liquid/methods
MH  - *Pesticide Residues/analysis
MH  - Tea/chemistry
PMC - PMC10574668
OTO - NOTNLM
OT  - Pu-erh tea
OT  - QuEChERS
OT  - UPLC-MS/MS
OT  - method validation
OT  - mycotoxins
OT  - pesticide residues
COIS- The authors declare that they have no conflict of interest.
EDAT- 2023/10/14 10:46
MHDA- 2023/10/23 01:18
PMCR- 2023/09/30
CRDT- 2023/10/14 01:19
PHST- 2023/07/24 00:00 [received]
PHST- 2023/09/08 00:00 [revised]
PHST- 2023/09/15 00:00 [accepted]
PHST- 2023/10/23 01:18 [medline]
PHST- 2023/10/14 10:46 [pubmed]
PHST- 2023/10/14 01:19 [entrez]
PHST- 2023/09/30 00:00 [pmc-release]
AID - molecules28196883 [pii]
AID - molecules-28-06883 [pii]
AID - 10.3390/molecules28196883 [doi]
PST - epublish
SO  - Molecules. 2023 Sep 30;28(19):6883. doi: 10.3390/molecules28196883.