PMID- 37839372
OWN - NLM
STAT- MEDLINE
DCOM- 20231129
LR  - 20231129
IS  - 1873-3336 (Electronic)
IS  - 0304-3894 (Linking)
VI  - 462
DP  - 2024 Jan 15
TI  - Comparative genomics reveals evidence of polycyclic aromatic hydrocarbon 
      degradation in the moderately halophilic genus Pontibacillus.
PG  - 132724
LID - S0304-3894(23)02008-3 [pii]
LID - 10.1016/j.jhazmat.2023.132724 [doi]
AB  - Polycyclic aromatic hydrocarbons (PAHs) are a common class of persistent organic 
      pollutants (POPs) that are widely distributed in various environments and pose 
      significant threats to both environmental and human health. The genus 
      Pontibacillus, a type of moderately halophilic bacteria, has demonstrated 
      potential for biodegrading aromatic compounds in high-salinity environments. 
      However, no previous study has comprehensively investigated the PAH degradation 
      mechanisms and environmental adaptability in the genus Pontibacillus. In this 
      study, we sequenced the whole genome of the PAH-degrading strain Pontibacillus 
      chungwhensis HN14 and conducted a comparative genomics analysis of genes 
      associated with PAH degradation, as well as salt and arsenic tolerance using ten 
      other Pontibacillus sp. strains. Here, we elucidated potential degradation 
      pathways for benzo[a]pyrene and phenanthrene, which were initiated by cytochrome 
      P450 monooxygenases, in most Pontibacillus strains. Moreover, four Pontibacillus 
      strains were selected to investigate the biodegradation of benzo[a]pyrene and 
      phenanthrene under high-salt (5% NaCl) stress, and all four strains exhibited 
      exceptional degradation abilities. The results of comparative genomics and 
      phenotypic analyses demonstrate that the genus Pontibacillus have the potential 
      to degrade polycyclic aromatic hydrocarbons in high-salinity environments, thus 
      providing valuable insights for biodegradation in extreme environments.
CI  - Copyright (c) 2023 Elsevier B.V. All rights reserved.
FAU - Yang, Haichen
AU  - Yang H
AD  - Department of Biology, Shantou University, Shantou, Guangdong 515063, PR China.
FAU - Qian, Zhihui
AU  - Qian Z
AD  - Department of Biology, Shantou University, Shantou, Guangdong 515063, PR China.
FAU - Liu, Yongjin
AU  - Liu Y
AD  - Department of Biology, Shantou University, Shantou, Guangdong 515063, PR China.
FAU - Yu, Fei
AU  - Yu F
AD  - Department of Biology, Shantou University, Shantou, Guangdong 515063, PR China.
FAU - Huang, Tongwang
AU  - Huang T
AD  - Department of Biology, Shantou University, Shantou, Guangdong 515063, PR China.
FAU - Zhang, Bing
AU  - Zhang B
AD  - Department of Biology, Shantou University, Shantou, Guangdong 515063, PR China.
FAU - Peng, Tao
AU  - Peng T
AD  - Department of Biology, Shantou University, Shantou, Guangdong 515063, PR China. 
      Electronic address: tpeng@stu.edu.cn.
FAU - Hu, Zhong
AU  - Hu Z
AD  - Department of Biology, Shantou University, Shantou, Guangdong 515063, PR China; 
      Guangdong Research Center of Offshore Environmental Pollution Control 
      Engineering, Shantou University, Shantou 515063, Guangdong, PR China. Electronic 
      address: hzh@stu.edu.cn.
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20231005
PL  - Netherlands
TA  - J Hazard Mater
JT  - Journal of hazardous materials
JID - 9422688
RN  - 0 (Polycyclic Aromatic Hydrocarbons)
RN  - 3417WMA06D (Benzo(a)pyrene)
RN  - 448J8E5BST (phenanthrene)
RN  - 0 (Phenanthrenes)
SB  - IM
MH  - Humans
MH  - *Polycyclic Aromatic Hydrocarbons/metabolism
MH  - Benzo(a)pyrene
MH  - *Phenanthrenes
MH  - Biodegradation, Environmental
MH  - Genomics
OTO - NOTNLM
OT  - Biodegradation
OT  - Genomic traits
OT  - PAHs
OT  - Pontibacillus
OT  - Salinity tolerance
COIS- Declaration of Competing Interest The authors declare that they have no known 
      competing financial interests or personal relationships that could have appeared 
      to influence the work reported in this paper.
EDAT- 2023/10/16 00:41
MHDA- 2023/11/29 06:42
CRDT- 2023/10/15 18:11
PHST- 2023/06/13 00:00 [received]
PHST- 2023/09/22 00:00 [revised]
PHST- 2023/10/04 00:00 [accepted]
PHST- 2023/11/29 06:42 [medline]
PHST- 2023/10/16 00:41 [pubmed]
PHST- 2023/10/15 18:11 [entrez]
AID - S0304-3894(23)02008-3 [pii]
AID - 10.1016/j.jhazmat.2023.132724 [doi]
PST - ppublish
SO  - J Hazard Mater. 2024 Jan 15;462:132724. doi: 10.1016/j.jhazmat.2023.132724. Epub 
      2023 Oct 5.