PMID- 37844711
OWN - NLM
STAT- MEDLINE
DCOM- 20240223
LR  - 20240223
IS  - 1873-2607 (Electronic)
IS  - 0749-3797 (Linking)
VI  - 66
IP  - 3
DP  - 2024 Mar
TI  - Social Determinants of Intrinsic Capacity: A National Cohort Study.
PG  - 559-567
LID - S0749-3797(23)00409-9 [pii]
LID - 10.1016/j.amepre.2023.10.008 [doi]
AB  - INTRODUCTION: Intrinsic capacity (IC), a composite of physical and mental 
      capacities, is a marker of healthy aging. Social determinants of health (SDOH), 
      namely the economic and social environments across a lifespan, are the most 
      fundamental factors influencing health outcomes and health disparities. However, 
      there is limited evidence on the influence of the individual and combined burden 
      of the SDOH on IC. METHODS: Data were obtained from the China Health and 
      Retirement Longitudinal Study (2011-2015), and data analysis was conducted in 
      2023. Linear mixed-effect regression was employed to investigate the association 
      between SDOH and IC in a longitudinal analysis. RESULTS: This study comprised 
      7,669 participants (mean [SD] age, 68.5 [7.1] years; 49.8% female; mean [SD] IC, 
      7.2 [1.6]). In the longitudinal analysis, all five SDOH domains were 
      independently and significantly associated with IC. The absence of social 
      association within the social and community context domain exhibited the weakest 
      association with IC (beta: -0.11 [95% CI -0.20, -0.02]), while illiteracy within the 
      education access and quality domain demonstrated the strongest association with 
      IC (beta: -0.51 [95% CI -0.60, -0.42]). Furthermore, the adverse effects of SDOH on 
      IC became more distinguishable with the cumulative number of SDOH variables 
      (coefficient for 2 SDOH, -0.41 [-0.64, -0.19]; 3 SDOH, -0.70 [-0.93, -0.48]; >/=4 
      SDOH, -1.10 [-1.33, -0.88]) compared with those without any SDOH. CONCLUSIONS: 
      Certain SDOH levels were significantly and negatively associated with IC. 
      Targeted interventions may be needed to improve SDOH in individuals at high risk 
      of poor IC.
CI  - Copyright (c) 2023 American Journal of Preventive Medicine. Published by Elsevier 
      Inc. All rights reserved.
FAU - Zhao, Binyu
AU  - Zhao B
AD  - Department of Nursing, The Fourth Affiliated Hospital, Zhejiang University School 
      of Medicine, Yiwu, Zhejiang, China; Institute of Nursing Research, Zhejiang 
      University School of Medicine, Hangzhou, Zhejiang, China.
FAU - Liu, Zuyun
AU  - Liu Z
AD  - Department of Big Data in Health Science School of Public Health and Center for 
      Clinical Big Data and Analytics of the Second Affiliated Hospital, The Key 
      Laboratory of Intelligent Preventive Medicine of Zhejiang Province, Zhejiang 
      University School of Medicine, Hangzhou, Zhejiang, China.
FAU - Fu, Yujia
AU  - Fu Y
AD  - Department of Nursing, The Fourth Affiliated Hospital, Zhejiang University School 
      of Medicine, Yiwu, Zhejiang, China; Institute of Nursing Research, Zhejiang 
      University School of Medicine, Hangzhou, Zhejiang, China.
FAU - Zhang, Huafang
AU  - Zhang H
AD  - Department of Nursing, The Fourth Affiliated Hospital, Zhejiang University School 
      of Medicine, Yiwu, Zhejiang, China.
FAU - Wu, Jingjie
AU  - Wu J
AD  - Nursing Department, Affiliated Sir Run Run Shaw Hospital, Zhejiang University 
      School of Medicine, Hangzhou, Zhejiang, China.
FAU - Lai, Chuyang
AU  - Lai C
AD  - Nursing Department, Affiliated Sir Run Run Shaw Hospital, Zhejiang University 
      School of Medicine, Hangzhou, Zhejiang, China.
FAU - Xue, Erxu
AU  - Xue E
AD  - Nursing Department, Affiliated Sir Run Run Shaw Hospital, Zhejiang University 
      School of Medicine, Hangzhou, Zhejiang, China.
FAU - Gao, Qisheng
AU  - Gao Q
AD  - School of Public Health, Hangzhou Medical College, Hangzhou, Zhejiang, China.
FAU - Shao, Jing
AU  - Shao J
AD  - Department of Nursing, The Fourth Affiliated Hospital, Zhejiang University School 
      of Medicine, Yiwu, Zhejiang, China; Institute of Nursing Research, Zhejiang 
      University School of Medicine, Hangzhou, Zhejiang, China. Electronic address: 
      11318202@zju.edu.cn.
LA  - eng
PT  - Journal Article
DEP - 20231014
PL  - Netherlands
TA  - Am J Prev Med
JT  - American journal of preventive medicine
JID - 8704773
SB  - IM
MH  - Humans
MH  - Female
MH  - Aged
MH  - Male
MH  - Cohort Studies
MH  - Longitudinal Studies
MH  - *Social Determinants of Health
MH  - China
MH  - *Data Analysis
EDAT- 2023/10/17 00:42
MHDA- 2024/02/23 06:43
CRDT- 2023/10/16 19:21
PHST- 2023/04/07 00:00 [received]
PHST- 2023/10/06 00:00 [revised]
PHST- 2023/10/09 00:00 [accepted]
PHST- 2024/02/23 06:43 [medline]
PHST- 2023/10/17 00:42 [pubmed]
PHST- 2023/10/16 19:21 [entrez]
AID - S0749-3797(23)00409-9 [pii]
AID - 10.1016/j.amepre.2023.10.008 [doi]
PST - ppublish
SO  - Am J Prev Med. 2024 Mar;66(3):559-567. doi: 10.1016/j.amepre.2023.10.008. Epub 
      2023 Oct 14.