PMID- 37852453 OWN - NLM STAT- MEDLINE DCOM- 20240315 LR - 20240315 IS - 1532-8406 (Electronic) IS - 0883-5403 (Linking) VI - 39 IP - 4 DP - 2024 Apr TI - Non-White Race and Concomitant Orthopedic Conditions Are Risk Factors for Failure to Achieve Clinically Relevant Improvement After Total Knee Arthroplasty. PG - 927-934 LID - S0883-5403(23)01026-4 [pii] LID - 10.1016/j.arth.2023.10.007 [doi] AB - BACKGROUND: Data from the American Joint Replacement Registry demonstrate that 1-year minimal clinically important difference (MCID) achievement rates after total knee arthroplasty (TKA) are substantially lower when using general patient reported outcome measures, such as Patient-Reported Outcomes Measurement Information System Physical Function (PROMIS-PF), than joint specific measures. The purpose of this study was to evaluate patient characteristics and outcomes associated with MCID achievement after TKA using the PROMIS-PF measure. METHODS: A retrospective review of 263 patients undergoing TKA with preoperative and 1-year postoperative PROMIS-PF scores from March 12, 2020 to February 8, 2022 was performed. Three multivariate models were built to evaluate predictors of MCID achievement. Preoperative predictors evaluated included demographics, comorbidities, history of spine and knee surgery, and baseline PROMIS-PF. Postoperative clinical outcomes evaluated included lengths of stay, discharge statuses, complications, and utilizations of other orthopaedic services. RESULTS: There were 109 patients (41%) who achieved an MCID at 1-year postoperatively. Non-white patients had 2.17 times lower odds of achieving MCID. No clinical outcomes assessed were independently predictive of MCID achievement. During the 1-year postoperative period, 63% of patients sought care for another orthopaedic condition. Patients requiring postoperative injections on another joint had a 2.27 times lower odds of achieving MCID. Those seen for spine conditions postoperatively had a 2.44 lower odds of achieving MCID. CONCLUSIONS: Race, postoperative injections, and treatment for spine conditions after TKA were independent predictors of failure to achieve MCID. These results may guide preoperative patient consultation and risk-adjustment in future studies using PROMIS-PF as an endpoint for evaluation of TKA outcomes. CI - Copyright (c) 2023 Elsevier Inc. All rights reserved. FAU - Baxter, Samantha N AU - Baxter SN AD - Luminis Health Orthopedics, Anne Arundel Medical Center, Annapolis, Maryland. FAU - Brennan, Jane C AU - Brennan JC AD - Luminis Health Orthopedics, Anne Arundel Medical Center, Annapolis, Maryland. FAU - Johnson, Andrea H AU - Johnson AH AD - Luminis Health Orthopedics, Anne Arundel Medical Center, Annapolis, Maryland. FAU - Chapa, Lauren AU - Chapa L AD - Luminis Health Orthopedics, Anne Arundel Medical Center, Annapolis, Maryland. FAU - Robbins, Shayla AU - Robbins S AD - Luminis Health Orthopedics, Anne Arundel Medical Center, Annapolis, Maryland. FAU - Turcotte, Justin J AU - Turcotte JJ AD - Luminis Health Orthopedics, Anne Arundel Medical Center, Annapolis, Maryland. FAU - King, Paul J AU - King PJ AD - Luminis Health Orthopedics, Anne Arundel Medical Center, Annapolis, Maryland. LA - eng PT - Journal Article DEP - 20231016 PL - United States TA - J Arthroplasty JT - The Journal of arthroplasty JID - 8703515 SB - IM MH - Humans MH - *Arthroplasty, Replacement, Knee/adverse effects MH - *Orthopedics MH - Treatment Outcome MH - Retrospective Studies MH - Risk Factors MH - Patient Reported Outcome Measures OTO - NOTNLM OT - clinically relevant improvement OT - outcomes OT - patient-reported outcomes OT - racial disparities OT - total knee arthroplasty EDAT- 2023/10/19 00:44 MHDA- 2024/03/15 06:44 CRDT- 2023/10/18 19:27 PHST- 2023/05/08 00:00 [received] PHST- 2023/09/26 00:00 [revised] PHST- 2023/10/02 00:00 [accepted] PHST- 2024/03/15 06:44 [medline] PHST- 2023/10/19 00:44 [pubmed] PHST- 2023/10/18 19:27 [entrez] AID - S0883-5403(23)01026-4 [pii] AID - 10.1016/j.arth.2023.10.007 [doi] PST - ppublish SO - J Arthroplasty. 2024 Apr;39(4):927-934. doi: 10.1016/j.arth.2023.10.007. Epub 2023 Oct 16.