PMID- 37853529
OWN - NLM
STAT- MEDLINE
DCOM- 20240301
LR  - 20240302
IS  - 1747-4949 (Electronic)
IS  - 1747-4930 (Print)
IS  - 1747-4930 (Linking)
VI  - 19
IP  - 3
DP  - 2024 Mar
TI  - Global stroke statistics 2023: Availability of reperfusion services around the 
      world.
PG  - 253-270
LID - 10.1177/17474930231210448 [doi]
AB  - BACKGROUND: Disparities in the availability of reperfusion services for acute 
      ischemic stroke are considerable globally and require urgent attention. 
      Contemporary data on the availability of reperfusion services in different 
      countries are used to provide the necessary evidence to prioritize where access 
      to acute stroke treatment is needed. AIMS: To provide a snapshot of published 
      literature on the provision of reperfusion services globally, including when 
      facilitated by telemedicine or mobile stroke unit services. METHODS: We searched 
      PubMed to identify original articles, published up to January 2023 for the most 
      recent, representative, and relevant patient-level data for each country. 
      Keywords included thrombolysis, endovascular thrombectomy and telemedicine. We 
      also screened reference lists of review articles, citation history of articles, 
      and the gray literature. The information is provided as a narrative summary. 
      RESULTS: Of 11,222 potentially eligible articles retrieved, 148 were included for 
      review following de-duplications and full-text review. Data were also obtained 
      from national stroke clinical registry reports, Registry of Stroke Care Quality 
      (RES-Q) and PRE-hospital Stroke Treatment Organization (PRESTO) repositories, and 
      other national sources. Overall, we found evidence of the provision of 
      intravenous thrombolysis services in 70 countries (63% high-income countries 
      (HICs)) and endovascular thrombectomy services in 33 countries (68% HICs), 
      corresponding to far less than half of the countries in the world. Recent data 
      (from 2019 or later) were lacking for 35 of 67 countries with known year of data 
      (52%). We found published data on 74 different stroke telemedicine programs (93% 
      in HICs) and 14 active mobile stroke unit pre-hospital ambulance services (80% in 
      HICs) around the world. CONCLUSION: Despite remarkable advancements in 
      reperfusion therapies for stroke, it is evident from available patient-level data 
      that their availability remains unevenly distributed globally. Contemporary 
      published data on availability of reperfusion services remain scarce, even in 
      HICs, thereby making it difficult to reliably ascertain current gaps in the 
      provision of this vital acute stroke treatment around the world.
FAU - Kim, Joosup
AU  - Kim J
AUID- ORCID: 0000-0002-4079-0428
AD  - Stroke and Ageing Research, Department of Medicine, School of Clinical Sciences 
      at Monash Health, Monash University, Clayton, VIC, Australia.
AD  - Stroke Theme, The Florey Institute of Neuroscience and Mental Health, Heidelberg, 
      VIC, Australia.
FAU - Olaiya, Muideen T
AU  - Olaiya MT
AUID- ORCID: 0000-0002-4070-0533
AD  - Stroke and Ageing Research, Department of Medicine, School of Clinical Sciences 
      at Monash Health, Monash University, Clayton, VIC, Australia.
FAU - De Silva, Deidre A
AU  - De Silva DA
AUID- ORCID: 0000-0002-7123-2381
AD  - Department of Neurology, Singapore General Hospital Campus, National Neuroscience 
      Institute, Singapore.
FAU - Norrving, Bo
AU  - Norrving B
AD  - Department of Clinical Sciences, Section of Neurology, Lund University, Skane 
      University Hospital, Lund, Sweden.
FAU - Bosch, Jackie
AU  - Bosch J
AD  - School of Rehabilitation Science, Population Health Research Institute, McMaster 
      University, Hamilton, ON, Canada.
FAU - De Sousa, Diana A
AU  - De Sousa DA
AUID- ORCID: 0000-0002-6702-7924
AD  - Department of Neurosciences (Neurology), Hospital de Santa Maria, University of 
      Lisbon, Lisbon, Portugal.
FAU - Christensen, Hanne K
AU  - Christensen HK
AD  - Department of Neurology, University of Copenhagen and Bispebjerg Hospital, 
      Copenhagen, Denmark.
FAU - Ranta, Anna
AU  - Ranta A
AUID- ORCID: 0000-0002-3223-3330
AD  - Department of Medicine, University of Otago, Wellington, Wellington, New Zealand.
FAU - Donnan, Geoffrey A
AU  - Donnan GA
AUID- ORCID: 0000-0001-6324-3403
AD  - Melbourne Brain Centre, The University of Melbourne, Royal Melbourne Hospital, 
      Parkville, VIC, Australia.
FAU - Feigin, Valery
AU  - Feigin V
AUID- ORCID: 0000-0002-6372-1740
AD  - National Institute for Stroke and Applied Neurosciences, Auckland University of 
      Technology, Auckland, New Zealand.
FAU - Martins, Sheila
AU  - Martins S
AD  - Neurology Department, Hospital Moinhos de Vento, Porto Alegre, Brazil.
FAU - Schwamm, Lee H
AU  - Schwamm LH
AD  - Yale School of Medicine, New Haven, CT, USA.
FAU - Werring, David J
AU  - Werring DJ
AUID- ORCID: 0000-0003-2074-1861
AD  - Stroke Research Centre, Department of Brain Repair and Rehabilitation, UCL Queen 
      Square Institute of Neurology, London, UK.
FAU - Howard, George
AU  - Howard G
AD  - Department of Biostatistics, School of Public Health, The University of Alabama 
      at Birmingham, Birmingham, AL, USA.
FAU - Owolabi, Mayowa
AU  - Owolabi M
AUID- ORCID: 0000-0003-1146-3070
AD  - Center for Genomic and Precision Medicine, University of Ibadan, Ibadan, Nigeria.
FAU - Pandian, Jeyaraj
AU  - Pandian J
AUID- ORCID: 0000-0003-0028-1968
AD  - Department of Neurology, Christian Medical College and Hospital, Ludhiana, India.
FAU - Mikulik, Robert
AU  - Mikulik R
AD  - Health Management Institute, Brno, Czech Republic.
AD  - Neurology Department, Bata Hospital, Zlin, Czech Republic.
FAU - Thayabaranathan, Tharshanah
AU  - Thayabaranathan T
AUID- ORCID: 0000-0003-2504-7772
AD  - Stroke and Ageing Research, Department of Medicine, School of Clinical Sciences 
      at Monash Health, Monash University, Clayton, VIC, Australia.
FAU - Cadilhac, Dominique A
AU  - Cadilhac DA
AUID- ORCID: 0000-0001-8162-682X
AD  - Stroke and Ageing Research, Department of Medicine, School of Clinical Sciences 
      at Monash Health, Monash University, Clayton, VIC, Australia.
AD  - Stroke Theme, The Florey Institute of Neuroscience and Mental Health, Heidelberg, 
      VIC, Australia.
LA  - eng
PT  - Journal Article
PT  - Review
DEP - 20240101
PL  - United States
TA  - Int J Stroke
JT  - International journal of stroke : official journal of the International Stroke 
      Society
JID - 101274068
SB  - IM
MH  - Humans
MH  - *Stroke/epidemiology/therapy
MH  - *Ischemic Stroke
MH  - Thrombectomy
MH  - Ambulances
MH  - Reperfusion
PMC - PMC10903148
OTO - NOTNLM
OT  - Stroke
OT  - mobile stroke unit
OT  - reperfusion
OT  - telemedicine
OT  - worldwide
COIS- Declaration of conflicting interestsThe author(s) declared no potential conflicts 
      of interest with respect to the research, authorship, and/or publication of this 
      article.
EDAT- 2023/10/19 06:46
MHDA- 2024/03/01 06:44
PMCR- 2024/02/29
CRDT- 2023/10/19 00:02
PHST- 2024/03/01 06:44 [medline]
PHST- 2023/10/19 06:46 [pubmed]
PHST- 2023/10/19 00:02 [entrez]
PHST- 2024/02/29 00:00 [pmc-release]
AID - 10.1177_17474930231210448 [pii]
AID - 10.1177/17474930231210448 [doi]
PST - ppublish
SO  - Int J Stroke. 2024 Mar;19(3):253-270. doi: 10.1177/17474930231210448. Epub 2024 
      Jan 1.