PMID- 37858156
OWN - NLM
STAT- MEDLINE
DCOM- 20231023
LR  - 20231123
IS  - 1476-511X (Electronic)
IS  - 1476-511X (Linking)
VI  - 22
IP  - 1
DP  - 2023 Oct 19
TI  - Effect of resistance training and high-intensity interval training on metabolic 
      parameters and serum level of Sirtuin1 in postmenopausal women with metabolic 
      syndrome: a randomized controlled trial.
PG  - 177
LID - 10.1186/s12944-023-01940-x [doi]
LID - 177
AB  - BACKGROUND: The present study analyzes the influence of resistance training (RT) 
      and high-intensity interval training (HIIT) on metabolic indices and serum levels 
      of Sirtuin1 (SIRT1) in postmenopausal women who suffer from the metabolic 
      syndrome (MetS). METHODS: 45 postmenopausal women aged 45-65 years with MetS were 
      divided into two intervention groups (RT and HIIT) and one control group, each 
      consisting of 15 people. The RT group performed resistance training for both the 
      upper and lower body, while the HIIT group completed 3 min(min) of high-intensity 
      training at 80-90% of their maximum heart rate (HRmax), followed by moderate 
      walking for 3 min at 55-65% of HRmax. These sessions were conducted for a 
      duration of eight weeks and three times a week, with the samples being collected 
      at the baseline and at the end of the treatment, i.e., week 8. RESULTS: The 
      results showed that weight, waist circumference, body mass index, fat mass, 
      low-density lipoprotein, triglyceride, cholesterol, fasting blood sugar (FBS), 
      hemoglobin A1c (HbA1C), systolic and diastolic blood pressure decreased, and 
      SIRT1 increased significantly in both training groups. Systolic blood pressure, 
      cholesterol, HbA1C, and FBS decreased more in the HIIT group. Skeletal muscle 
      mass and 1-repetition maximum (1-RM) increased more in the RT group. CONCLUSIONS: 
      RT and HIIT serve as one of the most effective strategies for therapeutically 
      treating patients with metabolic syndrome. TRIAL REGISTRATION: IRCT, 
      IRCT20221120056548N1. Registered 23 November 2022 - Retrospectively registered.
CI  - (c) 2023. BioMed Central Ltd., part of Springer Nature.
FAU - Kazemi, Saeid Shamlou
AU  - Kazemi SS
AUID- ORCID: 0000-0002-8133-0954
AD  - Faculty of Sport Sciences, Bu-Ali Sina University, Hamedan, Iran.
FAU - Heidarianpour, Ali
AU  - Heidarianpour A
AUID- ORCID: 0000-0001-8152-1489
AD  - Faculty of Sport Sciences, Bu-Ali Sina University, Hamedan, Iran. 
      a.heidarianpour@basu.ac.ir.
FAU - Shokri, Elnaz
AU  - Shokri E
AUID- ORCID: 0000-0002-8249-7107
AD  - Faculty of Sport Sciences, Bu-Ali Sina University, Hamedan, Iran.
LA  - eng
PT  - Journal Article
PT  - Randomized Controlled Trial
DEP - 20231019
PL  - England
TA  - Lipids Health Dis
JT  - Lipids in health and disease
JID - 101147696
RN  - EC 3.5.1.- (Sirtuin 1)
RN  - 0 (Glycated Hemoglobin)
RN  - 97C5T2UQ7J (Cholesterol)
SB  - IM
MH  - Humans
MH  - Female
MH  - *Metabolic Syndrome
MH  - *Resistance Training
MH  - Sirtuin 1
MH  - Glycated Hemoglobin
MH  - *High-Intensity Interval Training/methods
MH  - Postmenopause
MH  - Cholesterol
PMC - PMC10588115
OTO - NOTNLM
OT  - High-intensity interval training
OT  - Metabolic syndrome
OT  - Resistance training
OT  - Sirtuin1
COIS- The authors declare no competing interests.
EDAT- 2023/10/20 00:43
MHDA- 2023/10/23 01:18
PMCR- 2023/10/19
CRDT- 2023/10/20 00:00
PHST- 2023/07/01 00:00 [received]
PHST- 2023/10/11 00:00 [accepted]
PHST- 2023/10/23 01:18 [medline]
PHST- 2023/10/20 00:43 [pubmed]
PHST- 2023/10/20 00:00 [entrez]
PHST- 2023/10/19 00:00 [pmc-release]
AID - 10.1186/s12944-023-01940-x [pii]
AID - 1940 [pii]
AID - 10.1186/s12944-023-01940-x [doi]
PST - epublish
SO  - Lipids Health Dis. 2023 Oct 19;22(1):177. doi: 10.1186/s12944-023-01940-x.