PMID- 37871272
OWN - NLM
STAT- MEDLINE
DCOM- 20231101
LR  - 20231127
IS  - 1539-2864 (Electronic)
IS  - 0275-004X (Linking)
VI  - 43
IP  - 11
DP  - 2023 Nov 1
TI  - INTEGRATING MACULAR OPTICAL COHERENCE TOMOGRAPHY WITH ULTRAWIDE-FIELD IMAGING IN 
      A DIABETIC RETINOPATHY TELEMEDICINE PROGRAM USING A SINGLE DEVICE.
PG  - 1928-1935
LID - 10.1097/IAE.0000000000003883 [doi]
AB  - PURPOSE: To determine the effect of combined macular spectral-domain optical 
      coherence tomography (SD-OCT) and ultrawide field retinal imaging (UWFI) within a 
      telemedicine program. METHODS: Comparative cohort study of consecutive patients 
      with both UWFI and SD-OCT. Ultrawide field retinal imaging and SD-OOCT were 
      independently evaluated for diabetic macular edema (DME) and nondiabetic macular 
      abnormality. Sensitivity and specificity were calculated with SD-OCT as the gold 
      standard. RESULTS: Four hundred twenty-two eyes from 211 diabetic patients were 
      evaluated. Diabetic macular edema severity by UWFI was as follows: no DME 93.4%, 
      noncenter involved DME (nonciDME) 5.1%, ciDME 0.7%, ungradable DME 0.7%. SD-OCT 
      was ungradable in 0.5%. Macular abnormality was identified in 34 (8.1%) eyes by 
      UWFI and in 44 (10.4%) eyes by SD-OCT. Diabetic macular edema represented only 
      38.6% of referable macular abnormality identified by SD-OCT imaging. 
      Sensitivity/specificity of UWFI compared with SD-OCT was 59%/96% for DME and 
      33%/99% for ciDME. Sensitivity/specificity of UWFI compared with SDOCT was 3%/98% 
      for epiretinal membrane. CONCLUSION: Addition of SD-OCT increased the 
      identification of macular abnormality by 29.4%. More than 58.3% of the eyes 
      believed to have any DME on UWF imaging alone were false-positives by SD-OCT. The 
      integration of SD-OCT with UWFI markedly increased detection and reduced 
      false-positive assessments of DME and macular abnormality in a teleophthalmology 
      program.
FAU - Aiello, Lloyd Paul
AU  - Aiello LP
AD  - Joslin Diabetes Center, Beetham Eye Institute, Boston, Massachusetts; and.
AD  - Department of Ophthalmology, Harvard Medical School, Boston, Massachusetts.
FAU - Jacoba, Cris Martin P
AU  - Jacoba CMP
AD  - Joslin Diabetes Center, Beetham Eye Institute, Boston, Massachusetts; and.
FAU - Ashraf, Mohamed
AU  - Ashraf M
AD  - Joslin Diabetes Center, Beetham Eye Institute, Boston, Massachusetts; and.
AD  - Department of Ophthalmology, Harvard Medical School, Boston, Massachusetts.
FAU - Cavallerano, Jerry D
AU  - Cavallerano JD
AD  - Joslin Diabetes Center, Beetham Eye Institute, Boston, Massachusetts; and.
AD  - Department of Ophthalmology, Harvard Medical School, Boston, Massachusetts.
FAU - Tolson, Ann M
AU  - Tolson AM
AD  - Joslin Diabetes Center, Beetham Eye Institute, Boston, Massachusetts; and.
FAU - Tolls, Dorothy
AU  - Tolls D
AD  - Joslin Diabetes Center, Beetham Eye Institute, Boston, Massachusetts; and.
FAU - Sun, Jennifer K
AU  - Sun JK
AD  - Joslin Diabetes Center, Beetham Eye Institute, Boston, Massachusetts; and.
AD  - Department of Ophthalmology, Harvard Medical School, Boston, Massachusetts.
FAU - Silva, Paolo S
AU  - Silva PS
AUID- ORCID: 0000-0001-8024-9348
AD  - Joslin Diabetes Center, Beetham Eye Institute, Boston, Massachusetts; and.
AD  - Department of Ophthalmology, Harvard Medical School, Boston, Massachusetts.
LA  - eng
GR  - Massachusetts Lions Eye Research Fund/
PT  - Journal Article
PL  - United States
TA  - Retina
JT  - Retina (Philadelphia, Pa.)
JID - 8309919
SB  - IM
MH  - Humans
MH  - *Diabetic Retinopathy/diagnosis
MH  - Tomography, Optical Coherence/methods
MH  - *Macular Edema/diagnostic imaging
MH  - Cohort Studies
MH  - *Telemedicine
MH  - *Ophthalmology
MH  - Retrospective Studies
MH  - *Diabetes Mellitus
EDAT- 2023/10/23 18:42
MHDA- 2023/11/01 12:43
CRDT- 2023/10/23 16:06
PHST- 2023/11/01 12:43 [medline]
PHST- 2023/10/23 18:42 [pubmed]
PHST- 2023/10/23 16:06 [entrez]
AID - 00006982-202311000-00012 [pii]
AID - 10.1097/IAE.0000000000003883 [doi]
PST - ppublish
SO  - Retina. 2023 Nov 1;43(11):1928-1935. doi: 10.1097/IAE.0000000000003883.