PMID- 37877538
OWN - NLM
STAT- MEDLINE
DCOM- 20231127
LR  - 20231127
IS  - 1097-0096 (Electronic)
IS  - 0091-2751 (Linking)
VI  - 51
IP  - 9
DP  - 2023 Nov-Dec
TI  - Left ventricular reverse remodeling after transcatheter aortic valve replacement 
      for predominant aortic stenosis and mixed aortic valve disease.
PG  - 1453-1460
LID - 10.1002/jcu.23585 [doi]
AB  - BACKGROUND: Mixed aortic valve disease (MAVD) is a frequent concomitant valve 
      disease with unique cardiac pathological changes compared to predominant aortic 
      stenosis (PAS). The previous studies about the MAVD are contradictory. Therefore, 
      a new perspective is needed to assess the value of TAVR for this cohort of 
      patients. METHODS: From January 2018 to December 2021, 90 MAVD patients and 72 
      PAS patients who underwent TAVR in our hospital were collected. 1:1 propensity 
      score matching analysis was used to control the bias in patient selection. The 
      dynamic changes in left ventricular morphology and hemodynamics were compared by 
      generalized estimating equations. Univariate or multivariate logistic regression 
      analysis was used to screen for independent risk factors for the non-occurrence 
      of left ventricular reverse remodeling (non-LVRR). RESULTS: After the matching 
      procedure, 112 patients were included in the analysis (56 in each group). 
      Baseline characteristics were similar between the two groups. LVRR occurred in 
      both groups, but MAVD had greater left ventricular end-diastolic volume index and 
      left ventricular mass index, a higher incidence of mitral regurgitation (MR), and 
      a more pronounced transformation of ventricular geometry patterns. Post-operative 
      MR (odd ratio [OR]: 10.05; 95% confidence interval [CI]: 2.08-48.57; p < .001) 
      and coronary artery disease (OR: 2.82; 95% CI: 1.08-7.34; p = .034) were 
      independent risk factors for non-LVRR. CONCLUSION: LVRR also occurs in patients 
      with MAVD, post-operative MR and coronary artery disease were independent risk 
      factors for non-LVRR.
CI  - (c) 2023 Wiley Periodicals LLC.
FAU - Huang, Liangyan
AU  - Huang L
AUID- ORCID: 0009-0008-4367-6314
AD  - Department of Ultrasound, Second Affiliated Hospital (Xinqiao Hospital), Army 
      Medical University, Chongqing, China.
FAU - Lai, Xiaoyue
AU  - Lai X
AD  - Department of Ultrasound, Second Affiliated Hospital (Xinqiao Hospital), Army 
      Medical University, Chongqing, China.
FAU - Xu, Lei
AU  - Xu L
AD  - Department of Ultrasound, Second Affiliated Hospital (Xinqiao Hospital), Army 
      Medical University, Chongqing, China.
FAU - Zeng, Ziling
AU  - Zeng Z
AD  - Department of Ultrasound, Second Affiliated Hospital (Xinqiao Hospital), Army 
      Medical University, Chongqing, China.
FAU - Xia, Hongmei
AU  - Xia H
AD  - Department of Ultrasound, Second Affiliated Hospital (Xinqiao Hospital), Army 
      Medical University, Chongqing, China.
LA  - eng
PT  - Journal Article
DEP - 20231025
PL  - United States
TA  - J Clin Ultrasound
JT  - Journal of clinical ultrasound : JCU
JID - 0401663
SB  - IM
MH  - Humans
MH  - *Transcatheter Aortic Valve Replacement/adverse effects/methods
MH  - Aortic Valve/diagnostic imaging/surgery
MH  - *Coronary Artery Disease/complications
MH  - Treatment Outcome
MH  - Ventricular Function, Left
MH  - *Aortic Valve Stenosis/complications/diagnostic imaging/surgery
MH  - *Mitral Valve Insufficiency
MH  - Retrospective Studies
MH  - Ventricular Remodeling
MH  - Severity of Illness Index
OTO - NOTNLM
OT  - aortic stenosis
OT  - left ventricular reverse remodeling
OT  - mixed aortic valve disease
OT  - transcatheter aortic valve replacement
EDAT- 2023/10/25 12:42
MHDA- 2023/11/27 12:44
CRDT- 2023/10/25 07:33
PHST- 2023/09/07 00:00 [revised]
PHST- 2023/05/13 00:00 [received]
PHST- 2023/09/28 00:00 [accepted]
PHST- 2023/11/27 12:44 [medline]
PHST- 2023/10/25 12:42 [pubmed]
PHST- 2023/10/25 07:33 [entrez]
AID - 10.1002/jcu.23585 [doi]
PST - ppublish
SO  - J Clin Ultrasound. 2023 Nov-Dec;51(9):1453-1460. doi: 10.1002/jcu.23585. Epub 
      2023 Oct 25.