PMID- 37883927 OWN - NLM STAT- MEDLINE DCOM- 20231220 LR - 20231220 IS - 1423-0399 (Electronic) IS - 0042-1138 (Linking) VI - 107 IP - 10-12 DP - 2023 TI - Needle-Perc-Assisted Endoscopic Surgery in Treatment with Renal Staghorn Stones: A Prospective Randomized Controlled Study from a Large-Volume Stone Center. PG - 910-915 LID - 10.1159/000533955 [doi] AB - INTRODUCTION: The goal of this study was to evaluate the efficacy and safety of needle-perc-assisted endoscopic surgery (NAES) in the treatment of staghorn renal stones via a single-center prospective randomized controlled study. METHODS: A total of 219 patients with partial or complete staghorn renal stones were prospectively randomized into two groups between January 2020 and April 2022. In group A (n = 112), patients were treated with traditional standard access, multiple if necessary, and in group B (n = 107), only one standard access was made, and needle-perc was assisted to remove the residual stones in the same stage. All procedures were guided under ultrasound totally. Stone size, operating time, blood loss, pain score, complications, and other related characteristics were monitored and analyzed. RESULTS: Procedures were successful in all patients. The baseline characters were similar between the groups. The mean stone size was comparable (4.5 +/- 1.4 vs. 4.7 +/- 1.7, p = 0.35). The 1-month stone-free status was achieved in 85 patients (75.9%) in group A and 80 (74.8%) patients in group B (p = 0.72). The operation time was shorter in group A than B (75.1 +/- 28.1 min vs. 97.2 +/- 20.4 min, p = 0.02). A less blood loss (p = 0.01), shorter hospital stay (p = 0.04), lower pain score (p = 0.04), and lower severe complication rates (p = 0.03) were observed in group B. CONCLUSION: NAES reveals better postoperative recurrence compared with traditional multiple tracts method for treating staghorn renal stones. The stone-free rate was comparable between the two groups. CI - (c) 2023 S. Karger AG, Basel. FAU - Xiao, Bo AU - Xiao B AD - Department of Urology, Tsinghua University Affiliated Beijing Tsinghua Changgung Hospital, Tsinghua University Clinical Institute, Beijing, China. FAU - Diao, Xiaolin AU - Diao X AD - Department of Medicine, Peking University Hospital, Beijing, China. FAU - Zeng, Xue AU - Zeng X AD - Department of Urology, Tsinghua University Affiliated Beijing Tsinghua Changgung Hospital, Tsinghua University Clinical Institute, Beijing, China, cengx12@tsinghua.org.cn. FAU - Jin, Song AU - Jin S AD - Department of Urology, Tsinghua University Affiliated Beijing Tsinghua Changgung Hospital, Tsinghua University Clinical Institute, Beijing, China. FAU - Zhang, Gang AU - Zhang G AD - Department of Urology, Tsinghua University Affiliated Beijing Tsinghua Changgung Hospital, Tsinghua University Clinical Institute, Beijing, China. FAU - Bai, Wenjie AU - Bai W AD - Department of Urology, Tsinghua University Affiliated Beijing Tsinghua Changgung Hospital, Tsinghua University Clinical Institute, Beijing, China. FAU - Li, Jianxing AU - Li J AD - Department of Urology, Tsinghua University Affiliated Beijing Tsinghua Changgung Hospital, Tsinghua University Clinical Institute, Beijing, China. LA - eng PT - Journal Article PT - Randomized Controlled Trial DEP - 20231026 PL - Switzerland TA - Urol Int JT - Urologia internationalis JID - 0417373 SB - IM MH - Humans MH - Prospective Studies MH - *Nephrolithotomy, Percutaneous/methods MH - *Kidney Calculi/surgery MH - *Staghorn Calculi/surgery MH - Pain MH - Treatment Outcome MH - Retrospective Studies MH - *Nephrostomy, Percutaneous OTO - NOTNLM OT - Kidney OT - Needle-Perc OT - Percutaneous nephrolithotomy OT - Staghorn OT - Stone EDAT- 2023/10/27 00:43 MHDA- 2023/12/20 06:42 CRDT- 2023/10/26 18:22 PHST- 2023/03/15 00:00 [received] PHST- 2023/08/07 00:00 [accepted] PHST- 2023/12/20 06:42 [medline] PHST- 2023/10/27 00:43 [pubmed] PHST- 2023/10/26 18:22 [entrez] AID - 000533955 [pii] AID - 10.1159/000533955 [doi] PST - ppublish SO - Urol Int. 2023;107(10-12):910-915. doi: 10.1159/000533955. Epub 2023 Oct 26.