PMID- 37885412
OWN - NLM
STAT- Publisher
LR  - 20231114
IS  - 1443-1661 (Electronic)
IS  - 0915-5635 (Linking)
DP  - 2023 Oct 27
TI  - Endoscopic nasobiliary drainage versus endoscopic biliary stenting for 
      preoperative biliary drainage in patients with malignant hilar biliary 
      obstruction: Propensity score-matched multicenter comparative study.
LID - 10.1111/den.14712 [doi]
AB  - OBJECTIVES: For preoperative biliary drainage (PBD) of malignant hilar biliary 
      obstruction (MHBO), current guidelines recommend endoscopic nasobiliary drainage 
      (ENBD) due to the higher risk of cholangitis after endoscopic biliary stenting 
      (EBS) during the waiting period before surgery. However, few studies have 
      supported this finding. Therefore, we aimed to compare the outcomes of 
      preoperative ENBD and EBS in patients with MHBO. METHODS: Patients with MHBO who 
      underwent laparotomy for radical surgery after ENBD or EBS were included from 
      retrospectively collected data from 13 centers (January 2014 to December 2018). 
      We performed a 1:1 propensity score matching between the ENBD and EBS groups. 
      These patients were compared for the following: cholangitis and all adverse 
      events (AEs) after endoscopic biliary drainage (EBD) until surgery, time to 
      cholangitis development after EBD, postsurgical AEs, and in-hospital death after 
      surgery. RESULTS: Of the 414 patients identified, 355 were analyzed in this study 
      (226 for ENBD and 129 for EBS). The matched cohort included 63 patients from each 
      group. The proportion of cholangitis after EBD was similar between the two 
      groups (20.6% vs. 25.4%, P = 0.67), and no significant difference was observed in 
      the time to cholangitis development. The proportions of surgical site infections, 
      bile leaks, and in-hospital mortality rates were similar between the groups. 
      CONCLUSION: For PBD of MHBO, the proportion of AEs, including cholangitis, after 
      EBD until surgery was similar when either ENBD or EBS was used.
CI  - (c) 2023 Japan Gastroenterological Endoscopy Society.
FAU - Ishiwatari, Hirotoshi
AU  - Ishiwatari H
AUID- ORCID: 0000-0002-6719-4466
AD  - Division of Endoscopy, Shizuoka Cancer Center, Shizuoka, Japan.
FAU - Kawabata, Takanori
AU  - Kawabata T
AD  - Clinical Research Center, Shizuoka Cancer Center, Shizuoka, Japan.
FAU - Kawashima, Hiroki
AU  - Kawashima H
AUID- ORCID: 0000-0002-3720-781X
AD  - Department of Endoscopy, Nagoya University Hospital, Aichi, Japan.
FAU - Nakai, Yousuke
AU  - Nakai Y
AUID- ORCID: 0000-0001-7411-1385
AD  - Department of Gastroenterology, Graduate School of Medicine, The University of 
      Tokyo, Tokyo, Japan.
FAU - Miura, Shin
AU  - Miura S
AUID- ORCID: 0000-0002-9561-0754
AD  - Division of Gastroenterology, Tohoku University Graduate School of Medicine, 
      Miyagi, Japan.
FAU - Kato, Hironari
AU  - Kato H
AUID- ORCID: 0000-0003-1120-292X
AD  - Department of Gastroenterology and Hepatology, Okayama University Graduate School 
      of Medicine and Dentistry, Okayama, Japan.
FAU - Shiomi, Hideyuki
AU  - Shiomi H
AUID- ORCID: 0000-0002-7461-8538
AD  - Division of Gastroenterology, Department of Internal Medicine, Kobe University 
      Graduate School of Medicine, Hyogo, Japan.
AD  - Division of Gastroenterology and Hepato-Biliary-Pancreatology, Department of 
      Internal Medicine, Hyogo Medical University, Hyogo, Japan.
FAU - Fujimori, Nao
AU  - Fujimori N
AUID- ORCID: 0000-0003-4286-8804
AD  - Department of Medicine and Bioregulatory Science, Graduate School of Medical 
      Sciences, Kyushu University, Fukuoka, Japan.
FAU - Ogura, Takeshi
AU  - Ogura T
AUID- ORCID: 0000-0003-2916-6568
AD  - Endoscopy Center, Osaka Medical and Pharmaceutical University Hospital, Osaka, 
      Japan.
FAU - Inatomi, Osamu
AU  - Inatomi O
AD  - Division of Gastroenterology, Department of Medicine, Shiga University of Medical 
      Science, Shiga, Japan.
FAU - Kubota, Kensuke
AU  - Kubota K
AD  - Division of Gastroenterology, Yokohama City University Graduate School of 
      Medicine, Kanagawa, Japan.
FAU - Fujisawa, Toshio
AU  - Fujisawa T
AUID- ORCID: 0000-0001-7367-0767
AD  - Department of Gastroenterology, Graduate School of Medicine, Juntendo University, 
      Tokyo, Japan.
FAU - Takenaka, Mamoru
AU  - Takenaka M
AUID- ORCID: 0000-0001-7308-4311
AD  - Department of Gastroenterology and Hepatology, Kindai University Faculty of 
      Medicine, Osaka, Japan.
FAU - Mori, Hiroshi
AU  - Mori H
AD  - Department of Endoscopy, Nagoya University Hospital, Aichi, Japan.
FAU - Noguchi, Kensaku
AU  - Noguchi K
AD  - Department of Gastroenterology, Graduate School of Medicine, The University of 
      Tokyo, Tokyo, Japan.
FAU - Fujii, Yuki
AU  - Fujii Y
AD  - Department of Gastroenterology and Hepatology, Okayama University Graduate School 
      of Medicine and Dentistry, Okayama, Japan.
FAU - Sugiura, Teiichi
AU  - Sugiura T
AD  - Division of Hepato-Biliary-Pancreatic Surgery, Shizuoka Cancer Center, Shizuoka, 
      Japan.
FAU - Ideno, Noboru
AU  - Ideno N
AD  - Department of Surgery and Oncology, Graduate School of Medical Sciences, Kyushu 
      University, Fukuoka, Japan.
FAU - Nakafusa, Tomoki
AU  - Nakafusa T
AD  - Department of Surgery and Oncology, Graduate School of Medical Sciences, Kyushu 
      University, Fukuoka, Japan.
FAU - Masamune, Atsushi
AU  - Masamune A
AD  - Division of Gastroenterology, Tohoku University Graduate School of Medicine, 
      Miyagi, Japan.
FAU - Isayama, Hiroyuki
AU  - Isayama H
AUID- ORCID: 0000-0002-3308-9326
AD  - Department of Gastroenterology, Graduate School of Medicine, Juntendo University, 
      Tokyo, Japan.
FAU - Sasahira, Naoki
AU  - Sasahira N
AD  - Division of Hepato-Biliary-Pancreatic Medicine, Department of Gastroenterology, 
      Cancer Institute Hospital of the Japanese Foundation for Cancer Research, Tokyo, 
      Japan.
LA  - eng
PT  - Journal Article
DEP - 20231027
PL  - Australia
TA  - Dig Endosc
JT  - Digestive endoscopy : official journal of the Japan Gastroenterological Endoscopy 
      Society
JID - 9101419
SB  - IM
OTO - NOTNLM
OT  - endoscopic biliary stenting
OT  - endoscopic nasobiliary drainage
OT  - malignant hilar biliary obstruction
OT  - perihilar cholangiocarcinoma
OT  - preoperative biliary drainage
EDAT- 2023/10/27 06:42
MHDA- 2023/10/27 06:42
CRDT- 2023/10/27 04:16
PHST- 2023/07/09 00:00 [received]
PHST- 2023/10/24 00:00 [accepted]
PHST- 2023/10/27 06:42 [pubmed]
PHST- 2023/10/27 06:42 [medline]
PHST- 2023/10/27 04:16 [entrez]
AID - 10.1111/den.14712 [doi]
PST - aheadofprint
SO  - Dig Endosc. 2023 Oct 27. doi: 10.1111/den.14712.