PMID- 37890858 OWN - NLM STAT- MEDLINE DCOM- 20231129 LR - 20231130 IS - 2055-5822 (Electronic) IS - 2055-5822 (Linking) VI - 10 IP - 6 DP - 2023 Dec TI - Severe aortic insufficiency-induced cardiogenic shock treated with left atrial VA-ECMO and emergent valve-in-valve TAVR. PG - 3718-3724 LID - 10.1002/ehf2.14561 [doi] AB - Conventional venoarterial extracorporeal membrane oxygenation (VA-ECMO) places a functional afterload burden on the left ventricle. In the setting of acute severe aortic insufficiency-induced cardiogenic shock, the utility of VA-ECMO in combination with a failing valve may result in catastrophic haemodynamic consequences. This challenge is compounded when the culprit is a failing surgical bioprosthetic valve. We present a case of severe rapid-onset bioprosthetic aortic insufficiency-induced cardiogenic shock successfully resuscitated with left atrial VA-ECMO promptly followed by emergent percutaneous valve-in-valve transaortic valve replacement. We discuss the logistics, implications, and associated haemodynamic manifestations in utilizing this strategy for such disease processes. CI - (c) 2023 The Authors. ESC Heart Failure published by John Wiley & Sons Ltd on behalf of European Society of Cardiology. FAU - Golzarian, Hafez AU - Golzarian H AD - Internal Medicine Residency Program, Mercy Health-St. Rita's Medical Center, Lima, OH, USA. FAU - Thiel, Arielle AU - Thiel A AD - Structural Heart and Intervention Center, Mercy Health-St. Rita's Medical Center, 730 West Market Street, 2K Tower, Lima, OH, 45801, USA. FAU - Hempfling, Gerri AU - Hempfling G AD - Structural Heart and Intervention Center, Mercy Health-St. Rita's Medical Center, 730 West Market Street, 2K Tower, Lima, OH, 45801, USA. FAU - Otto, Michael AU - Otto M AD - Cardiothoracic Surgery, Mercy Health-St. Rita's Medical Center, Lima, OH, USA. FAU - Otto, Todd AU - Otto T AD - Cardiothoracic Surgery, Mercy Health-St. Rita's Medical Center, Lima, OH, USA. FAU - Shappell, Emily AU - Shappell E AD - Structural Heart and Intervention Center, Mercy Health-St. Rita's Medical Center, 730 West Market Street, 2K Tower, Lima, OH, 45801, USA. FAU - Racer, Lisa AU - Racer L AD - Structural Heart and Intervention Center, Mercy Health-St. Rita's Medical Center, 730 West Market Street, 2K Tower, Lima, OH, 45801, USA. FAU - Martz, Denise AU - Martz D AD - Structural Heart and Intervention Center, Mercy Health-St. Rita's Medical Center, 730 West Market Street, 2K Tower, Lima, OH, 45801, USA. FAU - Recker-Herman, Christine M AU - Recker-Herman CM AD - Department of Critical Care, Mercy Health-St. Rita's Medical Center, Lima, OH, USA. FAU - Laird, Amanda AU - Laird A AD - Department of Critical Care, Mercy Health-St. Rita's Medical Center, Lima, OH, USA. FAU - Cole, William C AU - Cole WC AD - Department of Critical Care, Mercy Health-St. Rita's Medical Center, Lima, OH, USA. FAU - Sirak, John AU - Sirak J AD - Cardiothoracic Surgery, Mercy Health-St. Rita's Medical Center, Lima, OH, USA. FAU - Patel, Sandeep M AU - Patel SM AD - Structural Heart and Intervention Center, Mercy Health-St. Rita's Medical Center, 730 West Market Street, 2K Tower, Lima, OH, 45801, USA. LA - eng PT - Case Reports DEP - 20231027 PL - England TA - ESC Heart Fail JT - ESC heart failure JID - 101669191 SB - IM MH - Humans MH - Shock, Cardiogenic/etiology/therapy MH - *Extracorporeal Membrane Oxygenation MH - *Transcatheter Aortic Valve Replacement/adverse effects MH - *Atrial Fibrillation MH - *Aortic Valve Insufficiency/complications/diagnosis PMC - PMC10682863 OTO - NOTNLM OT - Aortic insufficiency OT - Cardiogenic shock OT - Haemodynamics OT - LAVA-ECMO OT - Mechanical circulatory support OT - ViV-TAVR COIS- The authors have no financial or personal relationships to disclose. EDAT- 2023/10/28 11:42 MHDA- 2023/11/29 06:42 PMCR- 2023/10/27 CRDT- 2023/10/27 19:53 PHST- 2023/09/05 00:00 [revised] PHST- 2023/02/01 00:00 [received] PHST- 2023/10/03 00:00 [accepted] PHST- 2023/11/29 06:42 [medline] PHST- 2023/10/28 11:42 [pubmed] PHST- 2023/10/27 19:53 [entrez] PHST- 2023/10/27 00:00 [pmc-release] AID - EHF214561 [pii] AID - 10.1002/ehf2.14561 [doi] PST - ppublish SO - ESC Heart Fail. 2023 Dec;10(6):3718-3724. doi: 10.1002/ehf2.14561. Epub 2023 Oct 27.