PMID- 37892449
OWN - NLM
STAT- MEDLINE
DCOM- 20231030
LR  - 20231030
IS  - 2072-6643 (Electronic)
IS  - 2072-6643 (Linking)
VI  - 15
IP  - 20
DP  - 2023 Oct 16
TI  - Isolate Whey Protein Promotes Fluid Balance and Endurance Capacity Better Than 
      Isolate Casein and Carbohydrate-Electrolyte Solution in a Warm, Humid 
      Environment.
LID - 10.3390/nu15204374 [doi]
LID - 4374
AB  - Protein ingestion is known to enhance post-exercise hydration. Whether the type 
      of protein (i.e., whey, casein) can alter this response is unknown. Accordingly, 
      this study aimed to compare the effects of the addition of milk-derived whey 
      isolate or casein protein to carbohydrate-electrolyte (CE) drinks on 
      post-exercise rehydration and endurance capacity. Thirty male soldiers (age: 24 +/- 
      2.1 y; VO(2max): 49.3 +/- 4.7 mL/kg/min) were recruited. Upon losing ~2.2% of body 
      mass by running in warm and humid conditions (32.3  degrees C, 76% relative humidity 
      [RH]), participants ingested either a CE solution (66 g/L carbohydrate [CHO]), or 
      CE plus isolate whey protein (CEW, 44 g/L CHO, 22 g/L isolate whey), or CE plus 
      isolate casein protein (CEC, 44 g/L CHO, 22 g/L isolate casein) beverage in a 
      volume equal to 150% of body mass loss. At the end of the 3 h rehydration period, 
      a positive fluid balance was higher with CEW (0.22 L) compared to CEC (0.19 L) 
      and CE (0.12 L). Overall mean fluid retention was higher in CEW (80.35%) compared 
      with the CE (76.67%) and CEC trials (78.65%). The time of the endurance capacity 
      test [Cooper 2.4 km (1.5 miles) run test] was significantly higher in CEC (14.25 
      +/- 1.58 min) and CE [(12.90 +/- 1.01 min; (p = 0.035)] than in CEW [(11.40 +/- 1.41 
      min); (p = 0.001)]. The findings of this study indicate that the inclusion of 
      isolate whey protein in a CE solution yields superior outcomes in terms of 
      rehydration and enhanced endurance capacity, as compared to consuming the CE 
      solution alone or in conjunction with isolate casein protein.
FAU - Gholizadeh, Mahdi
AU  - Gholizadeh M
AUID- ORCID: 0000-0001-5398-2683
AD  - Exercise Physiology Research Center, Life Style Institute, Baqiyatallah 
      University of Medical Sciences, Tehran 1435916471, Iran.
FAU - Shakibaee, Abolfazl
AU  - Shakibaee A
AD  - Exercise Physiology Research Center, Life Style Institute, Baqiyatallah 
      University of Medical Sciences, Tehran 1435916471, Iran.
FAU - Bagheri, Reza
AU  - Bagheri R
AUID- ORCID: 0000-0003-1433-2906
AD  - Department of Exercise Physiology, University of Isfahan, Isfahan 81746-73441, 
      Iran.
FAU - Camera, Donny M
AU  - Camera DM
AD  - Department of Health and Biostatistics, Swinburne University, Melbourne, VIC 
      3122, Australia.
FAU - Shirvani, Hossein
AU  - Shirvani H
AD  - Exercise Physiology Research Center, Life Style Institute, Baqiyatallah 
      University of Medical Sciences, Tehran 1435916471, Iran.
FAU - Dutheil, Frederic
AU  - Dutheil F
AUID- ORCID: 0000-0002-1468-6029
AD  - Physiological and Psychosocial Stress, CNRS UMR 6024, LaPSCo, University Clermont 
      Auvergne, Witty Fit, 63000 Clermont-Ferrand, France.
AD  - Preventive and Occupational Medicine, University Hospital of Clermont-Ferrand 
      (CHU), 63000 Clermont-Ferrand, France.
LA  - eng
PT  - Journal Article
DEP - 20231016
PL  - Switzerland
TA  - Nutrients
JT  - Nutrients
JID - 101521595
RN  - 0 (Whey Proteins)
RN  - 0 (Caseins)
RN  - 0 (Dietary Carbohydrates)
RN  - 0 (Electrolytes)
SB  - IM
MH  - Male
MH  - Humans
MH  - Young Adult
MH  - Adult
MH  - Whey Proteins
MH  - *Caseins
MH  - *Dietary Carbohydrates/pharmacology
MH  - Exercise/physiology
MH  - Water-Electrolyte Balance
MH  - Electrolytes
MH  - Physical Endurance
PMC - PMC10610234
OTO - NOTNLM
OT  - fluid retention
OT  - net fluid balance
OT  - rehydration
COIS- The authors declare no conflict of interest.
EDAT- 2023/10/28 11:46
MHDA- 2023/10/30 06:46
PMCR- 2023/10/16
CRDT- 2023/10/28 01:04
PHST- 2023/09/19 00:00 [received]
PHST- 2023/10/11 00:00 [revised]
PHST- 2023/10/14 00:00 [accepted]
PHST- 2023/10/30 06:46 [medline]
PHST- 2023/10/28 11:46 [pubmed]
PHST- 2023/10/28 01:04 [entrez]
PHST- 2023/10/16 00:00 [pmc-release]
AID - nu15204374 [pii]
AID - nutrients-15-04374 [pii]
AID - 10.3390/nu15204374 [doi]
PST - epublish
SO  - Nutrients. 2023 Oct 16;15(20):4374. doi: 10.3390/nu15204374.