PMID- 37892503 OWN - NLM STAT- MEDLINE DCOM- 20231030 LR - 20231030 IS - 2072-6643 (Electronic) IS - 2072-6643 (Linking) VI - 15 IP - 20 DP - 2023 Oct 18 TI - Diet Quality and Consumption of Healthy and Unhealthy Foods Measured via the Global Diet Quality Score in Relation to Cardiometabolic Outcomes in Apparently Healthy Adults from the Mediterranean Region: The ATTICA Epidemiological Cohort Study (2002-2022). LID - 10.3390/nu15204428 [doi] LID - 4428 AB - The Global Diet Quality Score (GDQS) is a novel food-based score that assesses both nutrient adequacy and chronic disease risk, by evaluating healthy (GDQS+) and unhealthy foods (GDQS-). The aim of this study was to evaluate the association among GDQS, GDQS+, and GDQS- against the 20-year risk of cardiometabolic outcomes in a Mediterranean population. The sample was n = 2169 initially free of cardiovascular disease (CVD) participants of the ATTICA study (2002-2022) that participated in the 20-year follow-up. The incidence of CVD, hypertension, hypercholesterolemia, and type 2 diabetes mellitus (T2DM) was defined according to WHO-ICD-10 criteria. The GDQS was computed based on previously published instructions. In multivariate analyses, a higher diet quality, per 1/49 of the GDQS, was associated with an 8% [95% Confidence Interval-CI: 6-9%] and 2% [95% CI: 1-3%] lower CVD and T2DM risk, respectively. A higher consumption of healthy foods, per 1/32 of GDQS+, was associated with a 9% [95% CI: 7-11%] and 2% [95% CI: 1-3%] lower CVD and T2DM risk, respectively. Contrarily, a lower consumption of unhealthy foods (GDQS-) was not associated with cardiometabolic events in the adjusted models (all p value< 0.05). In clinical practice or future public health actions to ameliorate dietary habits and prevent CVD and T2DM, more attention should be focused on healthy foods that should be included in our diets. FAU - Damigou, Evangelia AU - Damigou E AD - Department of Nutrition and Dietetics, School of Health Sciences and Education, Harokopio University, 17676 Athens, Greece. FAU - Kouvari, Matina AU - Kouvari M AD - Department of Nutrition and Dietetics, School of Health Sciences and Education, Harokopio University, 17676 Athens, Greece. FAU - Chrysohoou, Christina AU - Chrysohoou C AD - First Cardiology Clinic, Medical School, National and Kapodistrian University of Athens, Hippokration Hospital, 15772 Athens, Greece. FAU - Barkas, Fotios AU - Barkas F AD - Department of Internal Medicine, Medical School, University of Ioannina, 45500 Ioannina, Greece. FAU - Kravvariti, Evrydiki AU - Kravvariti E AD - First Department of Propaedeutic Internal Medicine, Medical School, National and Kapodistrian University of Athens, Laiko General Hospital, 15772 Athens, Greece. FAU - Dalmyras, Dimitrios AU - Dalmyras D AD - Department of Nutrition and Dietetics, School of Health Sciences and Education, Harokopio University, 17676 Athens, Greece. FAU - Koutsogianni, Amalia D AU - Koutsogianni AD AD - First Department of Propaedeutic Internal Medicine, Medical School, National and Kapodistrian University of Athens, Laiko General Hospital, 15772 Athens, Greece. FAU - Tsioufis, Costas AU - Tsioufis C AD - First Cardiology Clinic, Medical School, National and Kapodistrian University of Athens, Hippokration Hospital, 15772 Athens, Greece. FAU - Pitsavos, Christos AU - Pitsavos C AD - First Cardiology Clinic, Medical School, National and Kapodistrian University of Athens, Hippokration Hospital, 15772 Athens, Greece. FAU - Liberopoulos, Evangelos AU - Liberopoulos E AD - First Department of Propaedeutic Internal Medicine, Medical School, National and Kapodistrian University of Athens, Laiko General Hospital, 15772 Athens, Greece. FAU - Sfikakis, Petros P AU - Sfikakis PP AD - First Department of Propaedeutic Internal Medicine, Medical School, National and Kapodistrian University of Athens, Laiko General Hospital, 15772 Athens, Greece. FAU - Panagiotakos, Demosthenes AU - Panagiotakos D AUID- ORCID: 0000-0001-8583-153X AD - Department of Nutrition and Dietetics, School of Health Sciences and Education, Harokopio University, 17676 Athens, Greece. LA - eng PT - Journal Article DEP - 20231018 PL - Switzerland TA - Nutrients JT - Nutrients JID - 101521595 SB - IM MH - Humans MH - Adult MH - Cohort Studies MH - *Diabetes Mellitus, Type 2/epidemiology/prevention & control/complications MH - Risk Factors MH - *Diet, Mediterranean MH - Follow-Up Studies MH - Diet MH - *Cardiovascular Diseases/epidemiology/prevention & control/etiology PMC - PMC10610374 OTO - NOTNLM OT - Global Diet Quality Score (GDQS) OT - cardiometabolic outcomes OT - cardiovascular disease OT - diabetes OT - diet quality OT - healthy foods OT - unhealthy foods COIS- The authors declare no conflict of interest. EDAT- 2023/10/28 11:43 MHDA- 2023/10/30 06:46 PMCR- 2023/10/18 CRDT- 2023/10/28 01:04 PHST- 2023/09/20 00:00 [received] PHST- 2023/10/16 00:00 [revised] PHST- 2023/10/17 00:00 [accepted] PHST- 2023/10/30 06:46 [medline] PHST- 2023/10/28 11:43 [pubmed] PHST- 2023/10/28 01:04 [entrez] PHST- 2023/10/18 00:00 [pmc-release] AID - nu15204428 [pii] AID - nutrients-15-04428 [pii] AID - 10.3390/nu15204428 [doi] PST - epublish SO - Nutrients. 2023 Oct 18;15(20):4428. doi: 10.3390/nu15204428.