PMID- 37894602
OWN - NLM
STAT- MEDLINE
DCOM- 20231030
LR  - 20231031
IS  - 1420-3049 (Electronic)
IS  - 1420-3049 (Linking)
VI  - 28
IP  - 20
DP  - 2023 Oct 17
TI  - Measuring the Residual Levels of Fenpyroximate and Its Z-Isomer in Citrus Using 
      Ultra-High-Performance Liquid Chromatography-Tandem Mass Spectrometry and 
      Assessing the Related Dietary Intake Risks.
LID - 10.3390/molecules28207123 [doi]
LID - 7123
AB  - Fenpyroximate is an efficient, broad-spectrum phenoxypyrazole acaricide which is 
      used for controlling various mites. In this study, we measured the levels of 
      terminal fenpyroximate residues in citrus fruits, and estimated the dietary 
      intake risks posed by fenpyroximate. To this end, a QuEChERS analytical method 
      was used in combination with ultra-high-performance liquid chromatography-tandem 
      mass spectrometry (UHPLC-MS/MS) to determine the residual levels of fenpyroximate 
      and its Z-isomer (Z-fenpyroximate) in citrus fruits collected from 12 fields 
      under good agricultural practices (GAPs). The average recoveries of fenpyroximate 
      in whole fruits and citrus flesh were 104-110% and 92-109%, respectively, with 
      corresponding RSDs of 1-4% and 1-3%. The average recoveries of Z-fenpyroximate 
      were 104-113% and 90-91%, respectively, with RSDs of 1-2% in both cases. Each 
      limit of quantification (LOQ) was 0.01 mg kg(-1). Fifteen days after application 
      with 56 mg kg(-1), the terminal residues of fenpyroximate in whole fruits and 
      citrus flesh were <0.010-0.18 mg kg(-1) and <0.010-0.063 mg kg(-1), respectively; 
      the corresponding values for total fenpyroximate (the sum of fenpyroximate and 
      Z-fenpyroximate) were <0.020-0.19 and <0.020-0.053 mg kg(-1). The levels of 
      terminal fenpyroximate residues in citrus fruit were less than the maximum 
      residue limits (MRLs) specified in all the existing international standards. In 
      addition, the risk quotients RQ(c) and RQ(a) were both less than 100%, indicating 
      that the long-term and short-term dietary intake risks posed to Chinese consumers 
      by fenpyroximate in citrus fruit are both acceptable after a 15-day harvest 
      interval.
FAU - Sun, Ruiqing
AU  - Sun R
AD  - Shanxi Center for Testing of Functional Agro-Products, Longcheng Campus, Shanxi 
      Agricultural University, No. 79, Longcheng Street, Taiyuan 030031, China.
FAU - Cao, Junli
AU  - Cao J
AUID- ORCID: 0000-0002-4089-3515
AD  - Shanxi Center for Testing of Functional Agro-Products, Longcheng Campus, Shanxi 
      Agricultural University, No. 79, Longcheng Street, Taiyuan 030031, China.
FAU - Li, Jindong
AU  - Li J
AD  - Shanxi Center for Testing of Functional Agro-Products, Longcheng Campus, Shanxi 
      Agricultural University, No. 79, Longcheng Street, Taiyuan 030031, China.
FAU - Qi, Yanli
AU  - Qi Y
AD  - Shanxi Center for Testing of Functional Agro-Products, Longcheng Campus, Shanxi 
      Agricultural University, No. 79, Longcheng Street, Taiyuan 030031, China.
FAU - Qin, Shu
AU  - Qin S
AD  - Shanxi Center for Testing of Functional Agro-Products, Longcheng Campus, Shanxi 
      Agricultural University, No. 79, Longcheng Street, Taiyuan 030031, China.
LA  - eng
GR  - 202102140601018/Key Research and Development Project of Shanxi/
GR  - 202203021222162/Youth Science Research for Basic Research Program of Shanxi/
PT  - Journal Article
DEP - 20231017
PL  - Switzerland
TA  - Molecules
JT  - Molecules (Basel, Switzerland)
JID - 100964009
RN  - 9W557V4RYA (fenpyroximate)
RN  - 0 (Pesticide Residues)
SB  - IM
MH  - Chromatography, High Pressure Liquid
MH  - *Citrus/chemistry
MH  - Tandem Mass Spectrometry/methods
MH  - *Pesticide Residues/analysis
PMC - PMC10609617
OTO - NOTNLM
OT  - citrus
OT  - dietary intake risk
OT  - fenpyroximate
OT  - pesticide residues
COIS- The authors declare no conflict of interest.
EDAT- 2023/10/28 11:46
MHDA- 2023/10/30 06:47
PMCR- 2023/10/17
CRDT- 2023/10/28 01:16
PHST- 2023/09/12 00:00 [received]
PHST- 2023/09/26 00:00 [revised]
PHST- 2023/10/03 00:00 [accepted]
PHST- 2023/10/30 06:47 [medline]
PHST- 2023/10/28 11:46 [pubmed]
PHST- 2023/10/28 01:16 [entrez]
PHST- 2023/10/17 00:00 [pmc-release]
AID - molecules28207123 [pii]
AID - molecules-28-07123 [pii]
AID - 10.3390/molecules28207123 [doi]
PST - epublish
SO  - Molecules. 2023 Oct 17;28(20):7123. doi: 10.3390/molecules28207123.