PMID- 3789854
OWN - NLM
STAT- MEDLINE
DCOM- 19870106
LR  - 20190628
IS  - 0003-4975 (Print)
IS  - 0003-4975 (Linking)
VI  - 42
IP  - 6
DP  - 1986 Dec
TI  - The Medtronic-Hall cardiac valve: 7 1/2 years' clinical experience.
PG  - 644-50
AB  - Clinical information on the Medtronic-Hall valve prosthesis was obtained by 
      reviewing the records of 379 patients, 164 of whom had aortic valve replacement 
      (AVR), 163 of whom had mitral valve replacement (MVR), and 52 of whom had double 
      valve replacement over 90 months (1,225 patient-years) (mean follow-up, 42.01 +/- 
      1.3 months [+/- standard error]). Mean age was 53.8 +/- 12 years. One hundred 
      ninety-three patients (50.9%) had some type of concomitant operation, such as 
      tricuspid annuloplasty, coronary artery bypass grafting, or resection of 
      ascending aortic aneurysm. Ninety-one percent were in New York Heart Association 
      (NYHA) Functional Class III or IV preoperatively. Early mortality and late 
      mortality were 7.7% (29 patients) and 13.5% (51 patients), respectively. The 
      actuarial survival at 7 1/2 years was 74.1 +/- 2.7% for the total group and 69.0 
      +/- 4.5% for those having AVR, 81.0 +/- 3.2% for those having MVR, and 67.0 +/- 
      8.9% for those having double valve replacement. All patients but 2 were 
      maintained on a regimen of chronic anticoagulation with warfarin sodium. 
      Twenty-six thromboembolic episodes occurred (2.1/100 patient-years): 13 after MVR 
      (2.3/100 patient-years), 11 after AVR (2.1/100 patient-years), and 2 after double 
      valve replacement (1.4/100 patient-years). Four thromboembolic episodes were 
      fatal; no valve thrombosis occurred. There were no structural failures. Of the 
      350 late survivors, 92% were in NYHA Functional Classes I and II. Total 
      valve-related complications have been minimal.(ABSTRACT TRUNCATED AT 250 WORDS)
FAU - Beaudet, R L
AU  - Beaudet RL
FAU - Poirier, N L
AU  - Poirier NL
FAU - Doyle, D
AU  - Doyle D
FAU - Nakhle, G
AU  - Nakhle G
FAU - Gauvin, C
AU  - Gauvin C
LA  - eng
PT  - Journal Article
PL  - Netherlands
TA  - Ann Thorac Surg
JT  - The Annals of thoracic surgery
JID - 15030100R
RN  - 5Q7ZVV76EI (Warfarin)
SB  - IM
MH  - Aortic Valve/surgery
MH  - Cardiopulmonary Bypass
MH  - Evaluation Studies as Topic
MH  - Female
MH  - Follow-Up Studies
MH  - Heart Valve Diseases/complications/mortality/surgery
MH  - *Heart Valve Prosthesis
MH  - Hemorrhage/epidemiology/mortality
MH  - Humans
MH  - Hypothermia, Induced
MH  - Male
MH  - Middle Aged
MH  - Mitral Valve/surgery
MH  - Postoperative Complications/epidemiology/mortality
MH  - Prosthesis Design
MH  - Prosthesis Failure
MH  - Thromboembolism/epidemiology/mortality
MH  - Tricuspid Valve/surgery
MH  - Warfarin/administration & dosage
EDAT- 1986/12/01 00:00
MHDA- 1986/12/01 00:01
CRDT- 1986/12/01 00:00
PHST- 1986/12/01 00:00 [pubmed]
PHST- 1986/12/01 00:01 [medline]
PHST- 1986/12/01 00:00 [entrez]
AID - S0003-4975(10)64598-5 [pii]
AID - 10.1016/s0003-4975(10)64598-5 [doi]
PST - ppublish
SO  - Ann Thorac Surg. 1986 Dec;42(6):644-50. doi: 10.1016/s0003-4975(10)64598-5.