PMID- 37900632
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20231031
IS  - 0975-7651 (Print)
IS  - 0976-6952 (Electronic)
IS  - 0975-7651 (Linking)
VI  - 14
IP  - 3
DP  - 2023 Sep
TI  - Primary Gastric Synovial Sarcoma in a Young Male: a Rare Case Report and Review 
      of Literature.
PG  - 690-693
LID - 10.1007/s13193-023-01738-4 [doi]
AB  - We are reporting a rare case of primary gastric synovial sarcoma in a young male. 
      Synovial sarcoma of the stomach is a very rare tumor. The common involved sites 
      of occurrence of synovial sarcomas are upper and lower extremities. In the 
      English literature, only 47 cases of primary synovial sarcoma of stomach have 
      been reported. Spindle-shaped tumor cells are the basic content of synovial 
      sarcomas with varying degrees of epithelial differentiation. The basic 
      classification of synovial sarcoma depends on the histological pattern and the 
      degree of differentiation and it is classified as monophasic, biphasic, and 
      poorly differentiated. Synovial sarcoma presents with classical chromosomal 
      translocation where they form fusion genes of SS18-SSX1, SS18-SSX2, and 
      SS18-SSX4. Fluorescence in situ hybridization (FISH) and reverse transcription 
      polymerase chain reaction (RT-PCR) are the molecular analysis techniques to 
      detect these fusion genes. As the available literature support is limited, the 
      role of adjuvant chemotherapy, radiation therapy, and intra-operative 
      lymphadenectomy is still unclear. However, surgical resection with clear margin 
      is the gold standard treatment.
CI  - (c) The Author(s), under exclusive licence to Indian Association of Surgical 
      Oncology 2023. Springer Nature or its licensor (e.g. a society or other partner) 
      holds exclusive rights to this article under a publishing agreement with the 
      author(s) or other rightsholder(s); author self-archiving of the accepted 
      manuscript version of this article is solely governed by the terms of such 
      publishing agreement and applicable law.
FAU - Kadam, Sachin S
AU  - Kadam SS
AUID- ORCID: 0000-0003-0578-9066
AD  - Dept of Surgical Oncology, Currae Cancer & Multispeciality Hospital, Mumbai, 
      India.
FAU - Kadam, Tejaswini
AU  - Kadam T
AD  - Dept of Ophthalmology, Shree Ramkrishna Netralaya Superspeciality Eye Hospital, 
      Mumbai, India.
LA  - eng
PT  - Case Reports
DEP - 20230329
PL  - India
TA  - Indian J Surg Oncol
JT  - Indian journal of surgical oncology
JID - 101532448
PMC - PMC10611643
OTO - NOTNLM
OT  - Biphasic
OT  - GIST
OT  - Gastric sarcoma
OT  - Monophasic
OT  - SS18-SSX1
OT  - Synovial sarcoma
OT  - Young
COIS- Conflict of InterestThe authors declare no competing interests.
EDAT- 2023/10/30 06:46
MHDA- 2023/10/30 06:47
PMCR- 2024/09/01
CRDT- 2023/10/30 04:37
PHST- 2023/02/24 00:00 [received]
PHST- 2023/03/16 00:00 [accepted]
PHST- 2024/09/01 00:00 [pmc-release]
PHST- 2023/10/30 06:47 [medline]
PHST- 2023/10/30 06:46 [pubmed]
PHST- 2023/10/30 04:37 [entrez]
AID - 1738 [pii]
AID - 10.1007/s13193-023-01738-4 [doi]
PST - ppublish
SO  - Indian J Surg Oncol. 2023 Sep;14(3):690-693. doi: 10.1007/s13193-023-01738-4. 
      Epub 2023 Mar 29.