PMID- 37901118
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20240102
IS  - 1868-8527 (Print)
IS  - 1868-8535 (Electronic)
IS  - 1868-8527 (Linking)
VI  - 14
IP  - 1
DP  - 2023 Jan
TI  - The Mindful Reappraisal of Pain Scale (MRPS): Validation of a New Measure of 
      Psychological Mechanisms of Mindfulness-Based Analgesia.
PG  - 192-204
LID - 10.1007/s12671-022-02034-y [doi]
AB  - OBJECTIVES: Mindfulness is theorized to decrease the affective amplification of 
      chronic pain by facilitating a shift from emotionally-laden, catastrophic pain 
      appraisals of nociceptive input to reappraising chronic pain as an innocuous 
      sensory signal that does not signify harm. Understanding of these hypothetical 
      psychological mechanisms of mindfulness-based analgesia has been limited by a 
      lack of direct measures. We conducted a series of psychometric and experimental 
      studies to develop and validate the Mindful Reappraisal of Pain Sensations Scale 
      (MPRS). METHODS: After item generation, we conducted exploratory and confirmatory 
      factor analyses of the MRPS in samples of opioid-treated chronic pain patients 
      both before (n=450; n=90) and after (n=222) participating in Mindfulness-Oriented 
      Recovery Enhancement (MORE). We then examined the convergent and divergent 
      validity of the MRPS. Finally, in data from a randomized clinical trial (n=250), 
      the MRPS was tested as a mediator of the effects of MORE on reducing chronic pain 
      severity. RESULTS: Exploratory and confirmatory factor analyses demonstrated the 
      single-factor structure of the MRPS. The MRPS also evidenced convergent and 
      divergent validity. Mindfulness training through MORE significantly increased 
      MRPS scores relative to supportive psychotherapy (F(4,425.03) = 16.15, p < .001). 
      Changes in MRPS scores statistically mediated the effect of MORE on reducing 
      chronic pain severity through 9-month follow-up. CONCLUSIONS: Taken together, 
      these studies demonstrate that the MRPS is a psychometrically sound and valid 
      measure of novel analgesic mechanisms of mindfulness including attentional 
      disengagement from affective pain appraisals and interoceptive exposure to pain 
      sensations.
FAU - Garland, Eric L
AU  - Garland EL
AD  - Center on Mindfulness and Integrative Health Intervention Development, College of 
      Social Work, University of Utah.
AD  - Veterans Health Care Administration VISN 19 Whole Health Flagship site located at 
      the VA Salt Lake City Health Care System, Salt Lake City, Utah.
FAU - Roberts, R Lynae
AU  - Roberts RL
AD  - Center on Mindfulness and Integrative Health Intervention Development, College of 
      Social Work, University of Utah.
FAU - Hanley, Adam W
AU  - Hanley AW
AD  - Center on Mindfulness and Integrative Health Intervention Development, College of 
      Social Work, University of Utah.
FAU - Zeidan, Fadel
AU  - Zeidan F
AD  - Department of Anesthesiology, University of California San Diego.
FAU - Keefe, Francis J
AU  - Keefe FJ
AD  - Department of Psychiatry and Behavioral Sciences, Duke University.
LA  - eng
GR  - R01 AT011772/AT/NCCIH NIH HHS/United States
GR  - R01 DA042033/DA/NIDA NIH HHS/United States
PT  - Journal Article
DEP - 20221216
PL  - United States
TA  - Mindfulness (N Y)
JT  - Mindfulness
JID - 101518348
PMC - PMC10611443
MID - NIHMS1888927
OTO - NOTNLM
OT  - chronic pain
OT  - decentering
OT  - interoceptive exposure
OT  - measurement
OT  - mindfulness
OT  - pain appraisal
COIS- ELG is the Director of the Center on Mindfulness and Integrative Health 
      Intervention Development. The Center provides Mindfulness-Oriented Recovery 
      Enhancement (MORE), mindfulness-based therapy, and cognitive behavioral therapy 
      in the context of research trials for no cost to research participants; however, 
      Dr. Garland has received honoraria and payment for delivering seminars, lectures, 
      and teaching engagements (related to training clinicians in mindfulness) 
      sponsored by institutions of higher education, government agencies, academic 
      teaching hospitals, and medical centers. Dr. Garland also receives royalties from 
      the sale of books related to MORE. Dr. Garland has also been a consultant and 
      licensor to BehaVR, LLC. No other authors have any related conflicts of interest 
      to disclose.
EDAT- 2023/10/30 06:46
MHDA- 2023/10/30 06:47
PMCR- 2024/01/01
CRDT- 2023/10/30 04:45
PHST- 2023/10/30 06:47 [medline]
PHST- 2023/10/30 06:46 [pubmed]
PHST- 2023/10/30 04:45 [entrez]
PHST- 2024/01/01 00:00 [pmc-release]
AID - 10.1007/s12671-022-02034-y [doi]
PST - ppublish
SO  - Mindfulness (N Y). 2023 Jan;14(1):192-204. doi: 10.1007/s12671-022-02034-y. Epub 
      2022 Dec 16.