PMID- 37904568
OWN - NLM
STAT- MEDLINE
DCOM- 20240101
LR  - 20240106
IS  - 1600-0412 (Electronic)
IS  - 0001-6349 (Print)
IS  - 0001-6349 (Linking)
VI  - 103
IP  - 1
DP  - 2024 Jan
TI  - Placental size at gestational week 36: Comparisons between ongoing pregnancies 
      and deliveries.
PG  - 85-92
LID - 10.1111/aogs.14700 [doi]
AB  - INTRODUCTION: We aimed to compare placental size and placental size relative to 
      fetal size (ratio) in ongoing pregnancies examined by magnetic resonance imaging 
      (MRI) at gestational week 36 with placental size among all deliveries at 
      gestational week 36 during the same time period. MATERIAL AND METHODS: Ongoing 
      unselected singleton pregnancies (n = 89) were examined by MRI at median 
      gestational week 36+5 days during 2017-2018, and placental and fetal volumes 
      (cm(3) ) were calculated. The placental size and ratio in ongoing pregnancies 
      were compared with placental size and ratio among all deliveries in Norway at 
      gestational week 36 (median gestational week 36+4 days) during 2016-2019 
      (n = 5582). For comparison of size, we converted volume (cm(3) ) in ongoing 
      pregnancies into grams as: cm(3)  x 1.05 (density of placental and fetal tissue). 
      RESULTS: In ongoing pregnancies, median placental size was 873  (interquartile 
      range [IQR] 265) grams and median size of all delivered placentas was 613 (IQR 
      290) grams. Placental size was smaller among the delivered placentas independent 
      of delivery mode: 760 (IQR 387) grams among elective cesarean deliveries 
      (n = 465) and 590 (IQR 189) grams among vaginal deliveries after spontaneous 
      onset of labor (n = 2478). Median ratio in ongoing pregnancies was higher than 
      among deliveries: 0.31 (IQR 0.08) vs 0.21 (IQR 0.08). The ratio was higher in 
      ongoing pregnancies independent of delivery mode: 0.24 (IQR 0.17) among elective 
      cesarean deliveries vs 0.21 (IQR 0.05) among vaginal deliveries after spontaneous 
      onset of labor. CONCLUSIONS: The placenta is larger in ongoing pregnancies than 
      among deliveries. This finding suggests that placental size decreases during 
      labor and delivery, possibly by transfer of blood to the fetus. Our finding also 
      suggests that reference values of placental size based on delivered placentas are 
      not valid for ongoing pregnancies.
CI  - (c) 2023 The Authors. Acta Obstetricia et Gynecologica Scandinavica published by 
      John Wiley & Sons Ltd on behalf of Nordic Federation of Societies of Obstetrics 
      and Gynecology (NFOG).
FAU - Peterson, Helene Fjeldvik
AU  - Peterson HF
AUID- ORCID: 0000-0002-4706-1885
AD  - Division of Obstetrics and Gynecology, Akershus University Hospital, Lorenskog, 
      Norway.
AD  - Institute of Clinical Medicine, University of Oslo, Oslo, Norway.
FAU - Eskild, Anne
AU  - Eskild A
AUID- ORCID: 0000-0002-2756-1583
AD  - Division of Obstetrics and Gynecology, Akershus University Hospital, Lorenskog, 
      Norway.
AD  - Institute of Clinical Medicine, University of Oslo, Oslo, Norway.
FAU - Sommerfelt, Silje
AU  - Sommerfelt S
AD  - Division of Obstetrics and Gynecology, Akershus University Hospital, Lorenskog, 
      Norway.
FAU - Hillestad, Vigdis
AU  - Hillestad V
AUID- ORCID: 0000-0001-5430-3398
AD  - Division of Obstetrics and Gynecology, Akershus University Hospital, Lorenskog, 
      Norway.
AD  - Institute of Clinical Medicine, University of Oslo, Oslo, Norway.
AD  - Department of Diagnostic Imaging, Akershus University Hospital, Lorenskog, 
      Norway.
LA  - eng
GR  - 269903/Akershus Universitetssykehus, Strategiske midler/
GR  - 277901/Helse Sor-Ost RHF/
GR  - 2020013/Helse Sor-Ost RHF/
PT  - Journal Article
DEP - 20231030
PL  - United States
TA  - Acta Obstet Gynecol Scand
JT  - Acta obstetricia et gynecologica Scandinavica
JID - 0370343
SB  - IM
MH  - Pregnancy
MH  - Female
MH  - Humans
MH  - *Placenta/diagnostic imaging
MH  - Delivery, Obstetric/methods
MH  - *Labor, Obstetric
MH  - Cesarean Section
MH  - Fetus
MH  - Gestational Age
PMC - PMC10755138
OTO - NOTNLM
OT  - birth
OT  - obstetrics
OT  - placenta
OT  - pregnancy
COIS- The authors have stated explicitly that there are no conflicts of interest in 
      connection with this article.
EDAT- 2023/10/31 06:42
MHDA- 2024/01/02 11:45
PMCR- 2023/10/30
CRDT- 2023/10/31 03:43
PHST- 2023/09/29 00:00 [revised]
PHST- 2023/05/15 00:00 [received]
PHST- 2023/10/02 00:00 [accepted]
PHST- 2024/01/02 11:45 [medline]
PHST- 2023/10/31 06:42 [pubmed]
PHST- 2023/10/31 03:43 [entrez]
PHST- 2023/10/30 00:00 [pmc-release]
AID - AOGS14700 [pii]
AID - 10.1111/aogs.14700 [doi]
PST - ppublish
SO  - Acta Obstet Gynecol Scand. 2024 Jan;103(1):85-92. doi: 10.1111/aogs.14700. Epub 
      2023 Oct 30.