PMID- 37908691
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20231102
IS  - 2168-8184 (Print)
IS  - 2168-8184 (Electronic)
IS  - 2168-8184 (Linking)
VI  - 15
IP  - 10
DP  - 2023 Oct
TI  - Propofol-Related Infusion Syndrome in a Child With Refractory Status Epilepticus: 
      Successful Resuscitation With Veno-Arterial Extracorporeal Membrane Oxygenation, 
      Continuous Renal Replacement Therapy, and Therapeutic Plasma Exchange.
PG  - e47866
LID - 10.7759/cureus.47866 [doi]
LID - e47866
AB  - Propofol is used for sedation, anxiolysis, anesthesia induction, and as an 
      anticonvulsant. In cases of refractory status epilepticus (RSE), propofol is more 
      efficient than barbiturates. We present a case of a 3-year-old female with RSE 
      who developed propofol-related infusion syndrome (PRIS) despite low dosage after 
      failed attempts with multiple anti-epileptic drips and bolus therapies. Careful 
      consideration must be made before initiating propofol administration for RSE. We 
      discuss our PRIS treatment approach with extracorporeal membrane oxygenation, 
      therapeutic plasma exchange, and continuous renal replacement therapy leading to 
      our patient recovering to baseline and being discharged home from the hospital.
CI  - Copyright (c) 2023, Calvano et al.
FAU - Calvano, Joshua
AU  - Calvano J
AD  - Department of Anesthesiology and Critical Care, University of New Mexico School 
      of Medicine, Albuquerque, USA.
FAU - Paluska, Matthew R
AU  - Paluska MR
AD  - Department of Anesthesiology, Rocky Vista University College of Osteopathic 
      Medicine, Englewood, USA.
FAU - Armijo, Arthur J
AU  - Armijo AJ
AD  - Department of Graduate Medical Education, Healthcare Corporation of 
      America/HealthOne, Lone Tree, USA.
FAU - Petersen, Timothy R
AU  - Petersen TR
AD  - Department of Graduate Medical Education, University of New Mexico School of 
      Medicine, Albuquerque, USA.
AD  - Department of Anesthesiology and Critical Care, University of New Mexico School 
      of Medicine, Albuquerque, USA.
AD  - Department of Obstetrics and Gynecology, University of New Mexico School of 
      Medicine, Albuquerque, USA.
FAU - Soneru, Codruta
AU  - Soneru C
AD  - Department of Anesthesiology and Critical Care, University of New Mexico School 
      of Medicine, Albuquerque, USA.
FAU - Broman, Alia
AU  - Broman A
AD  - Department of Pediatrics, University of Colorado School of Medicine, Denver 
      Health Medical Center, Denver, USA.
FAU - Lopez-Hernandez, Gloria
AU  - Lopez-Hernandez G
AD  - Department of Pediatrics, University of New Mexico School of Medicine, 
      Albuquerque, USA.
LA  - eng
PT  - Case Reports
DEP - 20231028
PL  - United States
TA  - Cureus
JT  - Cureus
JID - 101596737
PMC - PMC10613782
OTO - NOTNLM
OT  - continuous renal replacement therapy (crrt)
OT  - propofol infusion syndrome
OT  - refractory status epilepticus
OT  - therapeutic plasma exchange (tpe)
OT  - va-ecmo
COIS- The authors have declared that no competing interests exist.
EDAT- 2023/11/01 06:43
MHDA- 2023/11/01 06:44
PMCR- 2023/10/28
CRDT- 2023/11/01 03:59
PHST- 2023/10/28 00:00 [accepted]
PHST- 2023/11/01 06:44 [medline]
PHST- 2023/11/01 06:43 [pubmed]
PHST- 2023/11/01 03:59 [entrez]
PHST- 2023/10/28 00:00 [pmc-release]
AID - 10.7759/cureus.47866 [doi]
PST - epublish
SO  - Cureus. 2023 Oct 28;15(10):e47866. doi: 10.7759/cureus.47866. eCollection 2023 
      Oct.