PMID- 37908934
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20231102
IS  - 2168-8184 (Print)
IS  - 2168-8184 (Electronic)
IS  - 2168-8184 (Linking)
VI  - 15
IP  - 9
DP  - 2023 Sep
TI  - The Feline and the Swine: A Peculiar Case in an Allergy Clinic.
PG  - e46284
LID - 10.7759/cureus.46284 [doi]
LID - e46284
AB  - Cross-reactivity between mammalian proteins, such as that in Pork Cat Syndrome, 
      remains a topic of great interest. This syndrome, characterized by an 
      immunoglobulin E (IgE)-mediated response to porcine albumin triggered by 
      sensitization through cat epithelium, has been sparsely documented. We discuss a 
      41-year-old female who developed a pruritic rash within 30 minutes of consuming 
      pork. Notably, she exhibited elevated serum IgE levels with specific reactions to 
      cat dander, dog dander, and pork. A skin prick test for pork was positive. The 
      patient was treated conservatively with allergen avoidance, vitamin D 
      supplementation, fexofenadine, and doxycycline for systemic reactions, and 
      topical corticosteroids for localized skin reactions, yielding a resolution of 
      symptoms. This case underscores the significance of recognizing rare 
      cross-reactivities in allergy and immunology and the manifestations of Pork Cat 
      Syndrome, necessitating a comprehensive patient history and awareness for 
      improved diagnosis and management.
CI  - Copyright (c) 2023, Kile et al.
FAU - Kile, Mahlon R
AU  - Kile MR
AD  - Internal Medicine, Ross University School of Medicine, Bridgetown, BRB.
FAU - Lucas, Matthew D
AU  - Lucas MD
AD  - Internal Medicine, American University of the Caribbean School of Medicine, 
      Cupecoy, SXM.
FAU - Ganguli, Malika P
AU  - Ganguli MP
AD  - Medicine, Ross University School of Medicine, Bridgetown, BRB.
FAU - Dimov, Ves
AU  - Dimov V
AD  - Allergy and Immunology, Cleveland Clinic Hospital of Florida, Weston, USA.
LA  - eng
PT  - Case Reports
DEP - 20230930
PL  - United States
TA  - Cureus
JT  - Cureus
JID - 101596737
PMC - PMC10615587
OTO - NOTNLM
OT  - albumin sensitivity
OT  - cross-reactivity
OT  - cross-sensitization
OT  - meat allergy
OT  - pork cat syndrome
COIS- The authors have declared that no competing interests exist.
EDAT- 2023/11/01 06:43
MHDA- 2023/11/01 06:44
PMCR- 2023/09/30
CRDT- 2023/11/01 04:04
PHST- 2023/09/30 00:00 [accepted]
PHST- 2023/11/01 06:44 [medline]
PHST- 2023/11/01 06:43 [pubmed]
PHST- 2023/11/01 04:04 [entrez]
PHST- 2023/09/30 00:00 [pmc-release]
AID - 10.7759/cureus.46284 [doi]
PST - epublish
SO  - Cureus. 2023 Sep 30;15(9):e46284. doi: 10.7759/cureus.46284. eCollection 2023 
      Sep.