PMID- 37918409 OWN - NLM STAT- MEDLINE DCOM- 20231106 LR - 20231124 IS - 1665-1731 (Electronic) IS - 1405-9940 (Print) IS - 1665-1731 (Linking) VI - 93 IP - Supl DP - 2023 TI - Consensus document on the use of sacubitril/valsartan in patients with heart failure: Consejo Interamericano de Falla Cardiaca e Hipertension Pulmonar (CIFACAH) of the Inter-American Society of Cardiology (IASC). PG - 1-12 LID - 10.24875/ACM.23000036 [doi] AB - Heart failure (HF) is a significant event for public health. It has a prevalence between 1-2%, mortality rate between 7-17%, and hospitalization between 32-44%. This implies a risk to health and quality of life, but also great financial efforts for health systems. Sacubitril/valsartan is a medication recognized for its efficacy, and this consensus seeks to synthesize the available information regarding its use for the benefit of patients. This document consists of a description of the epidemiology of HF, pharmacology of the drug, clinical trials, use of the drug in cases with reduced ejection fraction, mildly reduced ejection fraction and preserved ejection fraction, available literature on HF guidelines, recommendations and conclusions. CI - Copyright: (c) 2023 Permanyer. FAU - Speranza, Mario AU - Speranza M AD - Departamento de Cardiologia, Hospital Clinica Biblica, San Jose, Costa Rica. FAU - Saldarriaga, Clara AU - Saldarriaga C AD - Departamento de Cardiologia, Clinica Cardio VID, Medellin, Colombia. FAU - Ramos, Carlos E AU - Ramos CE AD - Departamento de Cardiologia, Instituto Nacional Cardiopulmonar, Tegucigalpa, Honduras. FAU - Quesada, Daniel AU - Quesada D AD - Departamento de Cardiologia, Hospital San Vicente de Paul, Heredia, Costa Rica. FAU - Rossel, Victor AU - Rossel V AD - Departamento de Cardiologia, Hospital del Salvador. AD - Facultad de Medicina, Universidad de Chile, Santiago, Chile. FAU - Ventura-Umanzor, Jaime R AU - Ventura-Umanzor JR AD - Departamento de Cardiologia, Instituto Salvadoreno del Seguro Social, San Salvador, El Salvador. FAU - Pow-Chon, Freddy AU - Pow-Chon F AD - Departamento de Cardiologia, Hospital Luis Vernaza. AD - Departamento de Cardiologia, Universidad Espiritu Santo, Guayaquil, Ecuador. FAU - Alarco, Walter AU - Alarco W AD - Departamento de Cardiologia, Instituto Nacional Cardiovascular, Lima, Peru. FAU - Figueroa, Yolanda AU - Figueroa Y AD - Departamento de Cardiologia, Legacy Medical Center, Humacao, Puerto Rico. FAU - Magana, Antonio AU - Magana A AD - Departamento de Cardiologia, Centro Medico Nacional Siglo XXI, Instituto Mexicano del Seguro Social, Ciudad de Mexico, Mexico. FAU - Gomez-Mesa, Juan E AU - Gomez-Mesa JE AD - Departamento de Cardiologia, Fundacion Valle de Lili, Cali, Colombia. FAU - Rodriguez-Garcia, David AU - Rodriguez-Garcia D AD - Departamento de Cardiologia, Hospital Herrera Llerandi, Guatemala. LA - eng PT - Journal Article TT - Documento de consenso sobre el uso de sacubitrilo/valsartan en pacientes con insuficiencia cardiaca: Consejo Interamericano de Falla Cardiaca e Hipertension Pulmonar (CIFACAH) de la Sociedad Interamericana de Cardiologia (SIAC). PL - Mexico TA - Arch Cardiol Mex JT - Archivos de cardiologia de Mexico JID - 101126728 RN - 17ERJ0MKGI (sacubitril) RN - 0 (Tetrazoles) RN - 0 (Angiotensin Receptor Antagonists) RN - 80M03YXJ7I (Valsartan) SB - IM MH - Humans MH - United States MH - Quality of Life MH - Consensus MH - Tetrazoles/adverse effects MH - Stroke Volume MH - Angiotensin Receptor Antagonists/therapeutic use MH - Valsartan/adverse effects MH - *Heart Failure/drug therapy MH - *Ventricular Dysfunction, Left MH - *Cardiology MH - *Hypertension/drug therapy PMC - PMC10665007 OTO - NOTNLM OT - Consenso OT - Consensus OT - Heart failure OT - Insuficiencia cardiaca OT - Sacubitril-valsartan OT - Sacubitrilo-valsartan COIS- Ninguno. EDAT- 2023/11/03 00:42 MHDA- 2023/11/06 06:43 PMCR- 2023/10/27 CRDT- 2023/11/02 19:43 PHST- 2023/11/06 06:43 [medline] PHST- 2023/11/03 00:42 [pubmed] PHST- 2023/11/02 19:43 [entrez] PHST- 2023/10/27 00:00 [pmc-release] AID - j93/Supl/1 [pii] AID - 7974AX231-ACM-93-1 [pii] AID - 10.24875/ACM.23000036 [doi] PST - ppublish SO - Arch Cardiol Mex. 2023;93(Supl):1-12. doi: 10.24875/ACM.23000036.