PMID- 37926086
OWN - NLM
STAT- MEDLINE
DCOM- 20240206
LR  - 20240206
IS  - 1423-0097 (Electronic)
IS  - 1018-2438 (Linking)
VI  - 185
IP  - 2
DP  - 2024
TI  - Study of Allergy and Sensitization Relationship in Children and Parents in 
      Southern China.
PG  - 142-151
LID - 10.1159/000533896 [doi]
AB  - INTRODUCTION: The incidence of allergic diseases has increased globally, with 
      genetics playing an essential role in these conditions' development. However, 
      there is still a gap in understanding of how parental allergy status affects 
      children's allergies. METHODS: An electronic questionnaire was used to assess 
      allergy-related symptoms in kindergarten children and their parents, with a 
      clinical diagnosis and concurrent serum allergen-specific immunoglobulin E (IgE), 
      total IgE, and blood cell counts obtained. RESULTS: 88 family groups were 
      enrolled, with allergy prevalence of 85.2% in children, 50% in fathers, and 42% 
      in mothers. Allergic rhinoconjunctivitis was the most common allergic disease. 
      When the mother had an allergy, the children's allergy diagnosis rate was 91.3%; 
      86.67% when the father had an allergy; and 85.71% when both parents had 
      allergies. The child sensitization rate was 78.26% when the father had 
      sensitization, 59.09% just as the mother had sensitization, and 84.21% when both 
      parents had sensitization. Paternal allergies affected children's quality of life 
      due to allergic rhinitis but not their rhinitis symptoms. Maternal allergies or 
      sensitization did not significantly affect children's symptoms or quality-of-life 
      scores. CONCLUSION: The study found a positive correlation between childhood and 
      parental allergies, and further studies are needed to confirm the findings.
CI  - (c) 2023 S. Karger AG, Basel.
FAU - Gan, Hui
AU  - Gan H
AD  - Department of Clinical Laboratory, The Key Laboratory of Advanced 
      Interdisciplinary Studies Center, The First Affiliated Hospital of Guangzhou 
      Medical University, National Center for Respiratory Medicine, National Clinical 
      Research Center for Respiratory Disease, Guangzhou, China, hustgh@hotmail.com.
FAU - Huang, Zhifeng
AU  - Huang Z
AD  - Department of Clinical Laboratory, The Key Laboratory of Advanced 
      Interdisciplinary Studies Center, The First Affiliated Hospital of Guangzhou 
      Medical University, National Center for Respiratory Medicine, National Clinical 
      Research Center for Respiratory Disease, Guangzhou, China.
FAU - Zhu, Huiqing
AU  - Zhu H
AD  - Department of Clinical Laboratory, The Key Laboratory of Advanced 
      Interdisciplinary Studies Center, The First Affiliated Hospital of Guangzhou 
      Medical University, National Center for Respiratory Medicine, National Clinical 
      Research Center for Respiratory Disease, Guangzhou, China.
FAU - Li, Aoli
AU  - Li A
AD  - Department of Clinical Laboratory, The Key Laboratory of Advanced 
      Interdisciplinary Studies Center, The First Affiliated Hospital of Guangzhou 
      Medical University, National Center for Respiratory Medicine, National Clinical 
      Research Center for Respiratory Disease, Guangzhou, China.
FAU - Chen, Tong
AU  - Chen T
AD  - Department of Clinical Laboratory, The Key Laboratory of Advanced 
      Interdisciplinary Studies Center, The First Affiliated Hospital of Guangzhou 
      Medical University, National Center for Respiratory Medicine, National Clinical 
      Research Center for Respiratory Disease, Guangzhou, China.
FAU - Yin, Ziyu
AU  - Yin Z
AD  - Department of Clinical Laboratory, The Key Laboratory of Advanced 
      Interdisciplinary Studies Center, The First Affiliated Hospital of Guangzhou 
      Medical University, National Center for Respiratory Medicine, National Clinical 
      Research Center for Respiratory Disease, Guangzhou, China.
FAU - Sun, Baoqing
AU  - Sun B
AD  - Department of Clinical Laboratory, The Key Laboratory of Advanced 
      Interdisciplinary Studies Center, The First Affiliated Hospital of Guangzhou 
      Medical University, National Center for Respiratory Medicine, National Clinical 
      Research Center for Respiratory Disease, Guangzhou, China.
LA  - eng
PT  - Journal Article
DEP - 20231103
PL  - Switzerland
TA  - Int Arch Allergy Immunol
JT  - International archives of allergy and immunology
JID - 9211652
RN  - 37341-29-0 (Immunoglobulin E)
SB  - IM
MH  - Child
MH  - Female
MH  - Humans
MH  - Quality of Life
MH  - Parents
MH  - *Rhinitis/epidemiology
MH  - *Rhinitis, Allergic/epidemiology
MH  - Immunoglobulin E
OTO - NOTNLM
OT  - Allergic rhinitis
OT  - Allergy
OT  - Child
OT  - Parent
EDAT- 2023/11/06 00:41
MHDA- 2024/02/06 06:43
CRDT- 2023/11/05 18:25
PHST- 2023/06/17 00:00 [received]
PHST- 2023/08/29 00:00 [accepted]
PHST- 2024/02/06 06:43 [medline]
PHST- 2023/11/06 00:41 [pubmed]
PHST- 2023/11/05 18:25 [entrez]
AID - 000533896 [pii]
AID - 10.1159/000533896 [doi]
PST - ppublish
SO  - Int Arch Allergy Immunol. 2024;185(2):142-151. doi: 10.1159/000533896. Epub 2023 
      Nov 3.