PMID- 37933151 OWN - NLM STAT- MEDLINE DCOM- 20240319 LR - 20240319 IS - 1552-6941 (Electronic) IS - 1534-7346 (Linking) VI - 23 IP - 1 DP - 2024 Mar TI - Successful Revascularization, Angiosome Concept, and Multivessel Revascularization: Effects on Wound Healing: An Asian Perspective. PG - 12-18 LID - 10.1177/15347346231212330 [doi] AB - Endovascular treatment for revascularization in patients with chronic limb-threatening ischemia (CLTI), which is commonly found in patients with diabetes mellitus demonstrates a variable result of vessel patency, wound healing rate, and limb salvage rate. The angiosome concept has been adopted to determine the best target arterial path (TAP) for revascularization for wound healing in CLTI patients. Recent publications demonstrated the benefit of angiosome-targeted revascularization to guide the endovascular treatment in patients CLTI. The best TAP under angiosome concept by direct revascularization with at least 2 of 3 below-the-knee arteries runoff to restore in-line pulsatile blood flow to the ischemic tissue shows the best patency and high rate of wound healing. However, the clinical evidence and application of the angiosome concept in daily practice are difficult and not well established. The vascular territories, collateral vessel, wound area, and locations which associated with angiosome are varied. This article review aims to summarize the concept of angiosome-targeted revascularization and multivessel revascularization for application to the real-world practice under the evidence-based data. FAU - Orrapin, Saritphat AU - Orrapin S AUID- ORCID: 0000-0002-1330-6215 AD - Vascular Surgery Division, Department of Surgery, Faculty of Medicine, Thammasat University, Pathum Thani, Thailand. RINGGOLD: 37699 AD - Thammasat University-Center of Excellence for Diabetic Foot care (TU-CDC), Thammasat University Hospital, Pathum Thani, Thailand. FAU - Siribumrungwong, Boonying AU - Siribumrungwong B AD - Vascular Surgery Division, Department of Surgery, Faculty of Medicine, Thammasat University, Pathum Thani, Thailand. RINGGOLD: 37699 AD - Center of Excellence in Applied Epidemiology, Faculty of Medicine, Thammasat University Hospital, Thammasat University, Pathum Thani, Thailand. RINGGOLD: 176056 LA - eng PT - Journal Article DEP - 20231106 PL - United States TA - Int J Low Extrem Wounds JT - The international journal of lower extremity wounds JID - 101128359 SB - IM MH - Humans MH - *Amputation, Surgical MH - Treatment Outcome MH - Vascular Surgical Procedures/adverse effects MH - Lower Extremity/blood supply MH - Limb Salvage MH - Wound Healing MH - Ischemia/surgery MH - Retrospective Studies MH - Risk Factors MH - *Endovascular Procedures/adverse effects OTO - NOTNLM OT - angiosome concept OT - chronic limb-threatening ischemia OT - diabetic foot ulcers OT - lower extremity wound OT - multivessel revascularization COIS- Declaration of Conflicting InterestsThe author(s) declared no potential conflicts of interest with respect to the research, authorship, and/or publication of this article. EDAT- 2023/11/07 06:45 MHDA- 2024/03/19 06:44 CRDT- 2023/11/07 03:39 PHST- 2024/03/19 06:44 [medline] PHST- 2023/11/07 06:45 [pubmed] PHST- 2023/11/07 03:39 [entrez] AID - 10.1177/15347346231212330 [doi] PST - ppublish SO - Int J Low Extrem Wounds. 2024 Mar;23(1):12-18. doi: 10.1177/15347346231212330. Epub 2023 Nov 6.