PMID- 37937353 OWN - NLM STAT- MEDLINE DCOM- 20231216 LR - 20231216 IS - 1897-4279 (Electronic) IS - 0022-9032 (Linking) VI - 81 IP - 11 DP - 2023 TI - Discontinuation of cardiac implantable electronic device therapy after transvenous lead extraction. PG - 1113-1121 LID - 10.33963/v.kp.97655 [doi] AB - BACKGROUND: Patients with cardiac implantable electronic devices (CIEDs) may no longer be eligible for continued therapy. AIMS: The study aimed to assess the circumstances under which CIED reimplantation may not be necessary after transvenous lead extraction (TLE). METHODS: A retrospective analysis of 3646 TLE procedures was performed with assessment of indications for device reimplantation. RESULTS: Reimplantation was not performed immediately after TLE in 169 (4.6%) and, in long-term follow-up, in 146 (4.0%) of patients. No further need for CIED reimplantation was mostly associated with establishment of stable sinus rhythm (2.4%), conversion of sinus node dysfunction to chronic atrial fibrillation (AF; 1.4%), or improvement in left ventricular ejection fraction (LVEF) (0.9%). Independent prognostic factors were in the pacing groups: LVEF (odds ratio [OR], 1.03; 95% confidence interval [CI], 1.01-1.05; P <0.001), AF (OR, 3.8; 95% CI, 2.4-15.7; P <0.001), patients' age during first CIED implantation (OR, 0.97; 95% C, 0.96-0.98; P <0.001), and New York Heart Association (NYHA) class (OR, 0.616; 95% CI, 0.43-0.86; P <0.01); in the cardioverter-defibrillator group: LVEF (OR, 1.06; 95% CI, 1.04-1.09; P <001). Non-reimplanted patients had more complex procedures and more frequent complications, but survival after TLE was better in this group of patients. CONCLUSIONS: Reassessment of the need for continuation of CIED therapy should be considered in all patients following lead extraction and also before planned device replacement as TLE delay increases implant duration, complexity, and procedural risk. The predictors of non-reimplantation are a younger age during the first CIED implantation, lower NYHA class, presence of AF, and higher LVEF in pacemaker carriers, and, in the defibrillator group, only higher LVEF. A decision not to reimplant does not negatively affect the long-term prognosis. FAU - Kutarski, Andrzej AU - Kutarski A AD - Department of Cardiology, Medical University, Lublin, Poland. annapolewczyk@wp.pl. FAU - Jachec, Wojciech AU - Jachec W AD - 2nd Department of Cardiology, Zabrze, Faculty of Medical Science in Zabrze, Medical University of Silesia in Katowice, Katowice, Poland. FAU - Kosior, Jaroslaw AU - Kosior J AD - Department of Cardiology, Masovian Specialistic Hospital of Radom, Radom, Poland. FAU - Stec, Sebastian AU - Stec S AD - Division of Electrophysiology, Cardioneuroablation, Catheter Ablation and Cardiac Pacing, Subcarpathian Centre for Cardiovascular Interventions, Sanok, Poland. FAU - Nowosielecka, Dorota AU - Nowosielecka D AD - Department of Cardiology, the Pope John Paul II Province Hospital of Zamosc, Zamosc, Poland. FAU - Polewczyk, Anna AU - Polewczyk A AD - Department of Physiology, Pathophysiology and Clinical Immunology, Collegium Medicum of Jan Kochanowski University, Kielce, Poland. AD - Department of Cardiac Surgery, Swietokrzyskie Cardiology Center, Kielce, Poland. LA - eng PT - Journal Article DEP - 20231108 PL - Poland TA - Kardiol Pol JT - Kardiologia polska JID - 0376352 SB - IM MH - Humans MH - *Defibrillators, Implantable/adverse effects MH - Retrospective Studies MH - Stroke Volume MH - Treatment Outcome MH - Ventricular Function, Left MH - Device Removal MH - *Pacemaker, Artificial/adverse effects MH - *Atrial Fibrillation/etiology OTO - NOTNLM OT - implantable electronic device OT - long-term prognosis OT - loss of indications for pacing OT - superfluous CIED OT - unnecessary cardiac transvenous lead extraction EDAT- 2023/11/08 06:41 MHDA- 2023/12/17 09:42 CRDT- 2023/11/08 04:13 PHST- 2023/09/29 00:00 [received] PHST- 2023/09/29 00:00 [accepted] PHST- 2023/12/17 09:42 [medline] PHST- 2023/11/08 06:41 [pubmed] PHST- 2023/11/08 04:13 [entrez] AID - VM/OJS/J/97655 [pii] AID - 10.33963/v.kp.97655 [doi] PST - ppublish SO - Kardiol Pol. 2023;81(11):1113-1121. doi: 10.33963/v.kp.97655. Epub 2023 Nov 8.