PMID- 37951814 OWN - NLM STAT- Publisher LR - 20231111 IS - 1873-4588 (Electronic) IS - 0892-1997 (Linking) DP - 2023 Nov 9 TI - History of Previous Surgical Resection Promotes the Sclerosis of the Arytenoid Cartilage in Patients With Laryngeal Contact Granuloma. LID - S0892-1997(23)00328-4 [pii] LID - 10.1016/j.jvoice.2023.10.020 [doi] AB - OBJECTIVES: To explore the relationship between arytenoid cartilage sclerosis and a history of previous surgical resection in patients with laryngeal contact granuloma. METHODS: 167 patients with laryngeal contact granuloma treated from March 2016 to December 2018 were studied. The high-resolution computed tomography (HRCT) data of the sclerosis of arytenoid cartilage is divided into asymmetric sclerosis, bilateral sclerosis, and no sclerosis according to the range of sclerosis. The proportions of various ranges of sclerosis in two subgroups of patients were compared to patients with and without a history of previous surgical resection. RESULTS: The arytenoid cartilage sclerosis rate of 167 patients was 69.46%. The exact probability method showed that P < 0.001, suggesting that the distribution of arytenoid cartilage sclerosis was different in patients with and without a history of previous surgical resection, and there was a moderate correlation between the extent of arytenoid sclerosis and history of previous surgical resection (Cramer's V = 0.436, P < 0.001). There were 18 cases of bilateral sclerosis in patients with a history of previous surgical resection, of which 50% had contralateral recurrence after combined therapy (proton pump inhibitor (PPI) and glucocorticoid injection into granuloma via the thyrohyoid membrane approach), accounting for 75% of recurrence after combined therapy. CONCLUSION: Surgery promotes the expansion of arytenoid sclerosis, Patients with bilateral arytenoid sclerosis are prone to recurrence of contralateral laryngeal contact granuloma. CI - Copyright (c) 2023 The Voice Foundation. Published by Elsevier Inc. All rights reserved. FAU - Wang, Xiaoyu AU - Wang X AD - Department of otolaryngology, The Sixth Medical Center of PLA General Hospital, Beijing, China. FAU - Liu, Zhi AU - Liu Z AD - Department of otolaryngology, The Sixth Medical Center of PLA General Hospital, Beijing, China. FAU - Peng, Lili AU - Peng L AD - Department of otolaryngology, The Sixth Medical Center of PLA General Hospital, Beijing, China. FAU - Zhang, Jinhong AU - Zhang J AD - Department of otolaryngology, The Sixth Medical Center of PLA General Hospital, Beijing, China. FAU - Liu, Lianlian AU - Liu L AD - Department of otolaryngology, The Sixth Medical Center of PLA General Hospital, Beijing, China. FAU - Zhang, Chun AU - Zhang C AD - Department of otolaryngology, The Sixth Medical Center of PLA General Hospital, Beijing, China. FAU - Li, Jinrang AU - Li J AD - Department of otolaryngology, The Sixth Medical Center of PLA General Hospital, Beijing, China. Electronic address: entljr@sina.com. LA - eng PT - Journal Article DEP - 20231109 PL - United States TA - J Voice JT - Journal of voice : official journal of the Voice Foundation JID - 8712262 SB - IM OTO - NOTNLM OT - Arytenoid cartilage OT - Laryngeal contact granuloma OT - Recurrence OT - Sclerosis COIS- Declaration of Competing Interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper. EDAT- 2023/11/12 00:42 MHDA- 2023/11/12 00:42 CRDT- 2023/11/11 21:58 PHST- 2023/07/17 00:00 [received] PHST- 2023/10/11 00:00 [revised] PHST- 2023/10/11 00:00 [accepted] PHST- 2023/11/12 00:42 [medline] PHST- 2023/11/12 00:42 [pubmed] PHST- 2023/11/11 21:58 [entrez] AID - S0892-1997(23)00328-4 [pii] AID - 10.1016/j.jvoice.2023.10.020 [doi] PST - aheadofprint SO - J Voice. 2023 Nov 9:S0892-1997(23)00328-4. doi: 10.1016/j.jvoice.2023.10.020.