PMID- 37955143
OWN - NLM
STAT- MEDLINE
DCOM- 20231114
LR  - 20231114
IS  - 1471-1753 (Electronic)
IS  - 0954-6634 (Linking)
VI  - 34
IP  - 1
DP  - 2023 Dec
TI  - An updated systematic review and meta-analysis of efficacy and safety of Chinese 
      herbal medicine for treating atopic dermatitis.
PG  - 2268766
LID - 10.1080/09546634.2023.2268766 [doi]
AB  - BACKGROUND: This systematic review evaluated the Chinese herbal medicine (CHM) 
      for treating atopic dermatitis (AD). METHODS: PubMed, EMBASE, the Cochrane 
      library, the Wanfang database, and China National Knowledge Infrastructure (CNKI) 
      were searched for relevant randomized controlled trials (RCTs) from inception to 
      December 2021. Overall recovery rate, disease/symptom severity scoring, quality 
      of life (QoL), recurrence rate, and incidence of adverse events (AEs) were 
      evaluated. STATA SE 14.0 software was used for statistical analysis. RESULTS: 17 
      RCTs involving 1624 patients were eligible. CHM was associated with a higher 
      overall recovery rate (risk ratio [RR] = 1.15, 95% confidence interval [CI]: 
      1.05, 1.26, p = .003) and decreased recurrence rate (odds ratio [OR] = 0.19, 95% 
      CI: 0.07, 0.55, p = .002), both confirmed by sensitivity analyses. CHM could 
      decrease scoring atopic dermatitis index (MD = -0.61, 95% CI: -1.12, -0.11, 
      p = .017), however, sensitivity analysis revealed non-robustness. No significant 
      differences were found between the CHM and the control group in Eczema Area and 
      Severity Index, QoL, and the incidence of AEs. CONCLUSIONS: CHM was effective for 
      treating AD as it could improve the overall recovery rate and decrease the 
      recurrence rate. More studies are required to validate the potential of CHM on 
      disease/symptoms severity and QoL.
FAU - Jia, Jinjing
AU  - Jia J
AD  - State Key Laboratory of Dampness Syndrome of Chinese Medicine, The Second 
      Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou, 
      China.
AD  - Department of Dermatology, The Second Affiliated Hospital of Guangzhou University 
      of Chinese Medicine, Guangzhou, China.
AD  - Guangdong-Hong Kong-Macau Joint Lab on Chinese Medicine and Immune Disease 
      Research, Guangzhou University of Chinese Medicine, Guangzhou, China.
FAU - Gu, Sherman X
AU  - Gu SX
AD  - School of Health and Biomedical Sciences, STEM College, RMIT University, 
      Melbourne, Australia.
FAU - Mo, Xiumei
AU  - Mo X
AD  - State Key Laboratory of Dampness Syndrome of Chinese Medicine, The Second 
      Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou, 
      China.
AD  - Department of Dermatology, The Second Affiliated Hospital of Guangzhou University 
      of Chinese Medicine, Guangzhou, China.
AD  - Guangdong-Hong Kong-Macau Joint Lab on Chinese Medicine and Immune Disease 
      Research, Guangzhou University of Chinese Medicine, Guangzhou, China.
FAU - Liu, Junfeng
AU  - Liu J
AD  - State Key Laboratory of Dampness Syndrome of Chinese Medicine, The Second 
      Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou, 
      China.
AD  - Department of Dermatology, The Second Affiliated Hospital of Guangzhou University 
      of Chinese Medicine, Guangzhou, China.
AD  - Guangdong-Hong Kong-Macau Joint Lab on Chinese Medicine and Immune Disease 
      Research, Guangzhou University of Chinese Medicine, Guangzhou, China.
FAU - Chen, Dacan
AU  - Chen D
AD  - State Key Laboratory of Dampness Syndrome of Chinese Medicine, The Second 
      Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou, 
      China.
AD  - Department of Dermatology, The Second Affiliated Hospital of Guangzhou University 
      of Chinese Medicine, Guangzhou, China.
AD  - Guangdong-Hong Kong-Macau Joint Lab on Chinese Medicine and Immune Disease 
      Research, Guangzhou University of Chinese Medicine, Guangzhou, China.
LA  - eng
PT  - Journal Article
PT  - Meta-Analysis
PT  - Review
PT  - Systematic Review
DEP - 20231113
PL  - England
TA  - J Dermatolog Treat
JT  - The Journal of dermatological treatment
JID - 8918133
RN  - 0 (Drugs, Chinese Herbal)
SB  - IM
MH  - Humans
MH  - *Drugs, Chinese Herbal/adverse effects
MH  - *Dermatitis, Atopic/drug therapy
MH  - China
MH  - Quality of Life
MH  - Research Design
OTO - NOTNLM
OT  - Atopic dermatitis
OT  - Chinese herbal medicine
OT  - atopic eczema
OT  - meta-analysis
EDAT- 2023/11/13 06:42
MHDA- 2023/11/14 06:43
CRDT- 2023/11/13 05:27
PHST- 2023/11/14 06:43 [medline]
PHST- 2023/11/13 06:42 [pubmed]
PHST- 2023/11/13 05:27 [entrez]
AID - 10.1080/09546634.2023.2268766 [doi]
PST - ppublish
SO  - J Dermatolog Treat. 2023 Dec;34(1):2268766. doi: 10.1080/09546634.2023.2268766. 
      Epub 2023 Nov 13.