PMID- 37963176 OWN - NLM STAT- MEDLINE DCOM- 20231216 LR - 20231216 IS - 1466-447X (Electronic) IS - 0264-0414 (Linking) VI - 41 IP - 16 DP - 2023 Sep TI - Effects of increasing light versus moderate-to-vigorous physical activity on cardiometabolic health in Chinese adults with obesity. PG - 1547-1557 LID - 10.1080/02640414.2023.2282278 [doi] AB - Increasing daily physical activity (PA) is a practical way to decrease the risk of cardiometabolic diseases, while the studies on exercise intensity remain limited. The purpose of the present study was to compare the effects of increasing light PA (LPA) or moderate-to-vigorous PA (MVPA) for 12 weeks on cardiometabolic markers in Chinese adults with obesity. Fifty-three adults were randomly assigned to the 1) control group, 2) LPA group, and 3) MVPA group in free-living settings. The intervention effects on body composition, cardiorespiratory fitness, and cardiometabolic biomarkers were analysed using a generalized estimated equation model adjusted for baseline values and potential confounders. Compared with the control group, the MVPA group showed improvements in body composition, lipids, C-peptide, monocyte chemoattractant protein-1 (MCP-1), interleukin-8, leptin, and E-selectin. A favourable change in triglycerides and E-selectin were observed in the LPA group when compared to the control group. Lastly, improvements in waist circumference, C-reactive protein, and MCP-1 were observed in the MVPA group when compared to those in the LPA group. Although increasing both LPA and MVPA improved certain cardiometabolic biomarkers, the latter may have more benefits. These findings imply that MVPA may reduce cardiometabolic disease risk more effectively than LPA, especially in Chinese adults with obesity. FAU - Zheng, Chen AU - Zheng C AD - Department of Sports Science and Physical Education, The Chinese University of Hong Kong, Hong Kong, China. AD - Department of Health and Physical Education, The Education University of Hong Kong, Hong Kong, China. FAU - Gill, Jason M R AU - Gill JMR AD - Institute of Cardiovascular and Medical Sciences, University of Glasgow, Glasgow, UK. FAU - Sun, Feng Hua AU - Sun FH AD - Department of Health and Physical Education, The Education University of Hong Kong, Hong Kong, China. FAU - Huang, Wendy Yajun AU - Huang WY AD - Department of Sport, Physical Education and Health, Hong Kong Baptist University, Hong Kong, China. FAU - Sheridan, Sinead AU - Sheridan S AD - Department of Sports Science and Physical Education, The Chinese University of Hong Kong, Hong Kong, China. FAU - Chen, Xiang-Ke AU - Chen XK AD - Department of Health Technology and Informatics, The Hong Kong Polytechnic University, Hong Kong, China. FAU - Wu, Yalan AU - Wu Y AD - School of Biomedical Sciences, The Chinese University of Hong Kong, Hong Kong, China. FAU - Wong, Chun-Kwok AU - Wong CK AD - Department of Chemical Pathology, The Chinese University of Hong Kong, Hong Kong, China. FAU - Tian, Xiao Yu AU - Tian XY AD - School of Biomedical Sciences, The Chinese University of Hong Kong, Hong Kong, China. FAU - Wong, Stephen Heung-Sang AU - Wong SH AUID- ORCID: 0000-0002-6821-4545 AD - Department of Sports Science and Physical Education, The Chinese University of Hong Kong, Hong Kong, China. LA - eng PT - Journal Article PT - Randomized Controlled Trial DEP - 20231211 PL - England TA - J Sports Sci JT - Journal of sports sciences JID - 8405364 RN - 0 (E-Selectin) RN - 0 (Biomarkers) SB - IM MH - Adult MH - Humans MH - *E-Selectin MH - Sedentary Behavior MH - Obesity MH - Exercise MH - *Cardiovascular Diseases/prevention & control MH - Biomarkers MH - China MH - Waist Circumference OTO - NOTNLM OT - Exercise OT - biomarkers OT - cardiovascular disease OT - endothelial function EDAT- 2023/11/14 18:42 MHDA- 2023/12/17 13:19 CRDT- 2023/11/14 13:43 PHST- 2023/12/17 13:19 [medline] PHST- 2023/11/14 18:42 [pubmed] PHST- 2023/11/14 13:43 [entrez] AID - 10.1080/02640414.2023.2282278 [doi] PST - ppublish SO - J Sports Sci. 2023 Sep;41(16):1547-1557. doi: 10.1080/02640414.2023.2282278. Epub 2023 Dec 11.